Báo cáo y học: " Indications that "codon boundaries" are physico-chemically defined and that protein-folding information is contained in the redundant exon bases" pot
Báo cáo y học: " Indications that "codon boundaries" are physico-chemically defined and that protein-folding information is contained in the redundant exon bases" pot
... purposes)Theoretical Biology and Medical ModellingOpen AccessResearch Indications that "codon boundaries" are physico-chemically defined and that protein-folding information is contained ... subsequences containing only the 1st and 3rd codon letters (13) are compared. The black dots in the RCMs indicate amino acids that are within 6Å of each other in the protein structure. The colored ... proteome, the precision of translation is astonishingly good. Such physical precision is not possi-ble without a massive and consistent physico-chemicalunderpinning. Therefore, discovery of the existence...
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Báo cáo y học: "A cross-sectional analysis of video games and attention deficit hyperactivity disorder symptoms in adolescents" pps
... past year? YES NO If yes, how many times?Have you been in a physical fight in the past year? YES NO If yes, how many times?Have you been arrested in the past year? YES NO If yes, how many times?Do ... Further advances in technology led to the creation of the telephone, radio, and television. Recently, the Internet has become the pinnacle of interchange in the modern world and facilitates many ... or duties in the workplace26 has difficulty playing or engaging in leisure activities quietly27 Easily frustrated in effortsThank you for taking part in our survey. All results are confidential....
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Báo cáo y học: "Advanced glycation end-product (AGE)-damaged IgG and IgM autoantibodies to IgG-AGE in patients with early synovitis." ppt
... amounts to increase in the spondyl-arthropathy group and, conversely, fall slightly in the RAgroup at the second visit. This may reflect the lower use ofprednisone in the spondylarthropathy patients ... expression, which is induced by AGE,can contribute to the inflammatory cycle by the inductionof proinflammatory cytokines, via the nuclear factor-κBpathway [21]. No studies have yet examined RAGEexpression ... on the basis of having peripheral joint synovitis and not axialdisease, the presence of ‘inflammatory spinal pain’, whenpresent, was insufficient as the only major EuropeanSpondlyarthropathy...
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Báo cáo y học: "Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study" doc
... decreased functional capacity [10], or by the underlying inflammatory process. There is growing evi-dence that atherosclerosis is an inflammatory disease [11,12].Moreover, inflammation might cause ... cardiovascular risk; for example,a DMARD could increase the cardiovascular risk by causinghypertension and this increased risk would disappear aftercorrecting for hypertension.A third analysis was ... purposes)modifying antirheumatic drugs (DMARDs) [17]. There are some indications that DMARDs can alter cardiovascular riskeither by influencing atherosclerotic processes directlythrough inflammation or indirectly...
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Báo cáo y học: "A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity" doc
... geographically defined area in the middle and southern parts of Sweden during the period fromMay 1996 to 2005. A case was defined as a person in the study base who, during the study period and for the ... pathway so that it mainly influ-ences the clinical disease in RF-negative RA, specifically in men. However, it is not impossible that this pathway play a rolealso in other subtypes of RA. The ... on inflammation and autoimmunity. It is hoped that thisfinding will help to elucidate the complex genetics that underlieRA and autoimmunity.Competing interests The authors declare that they...
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Báo cáo y học: " Differential toll-like receptor 3 (TLR3) expression and apoptotic response to TLR3 agonist in human neuroblastoma cells" docx
... differentially expressed in human NB tissues and cells. The histologi cal study in human NB tissues reveals that TLR3 expression is pre-sent mainly in the cytoplasm of ganglion cells of GNB,but rare ... signaling using neutralizing antibody orsmall interference RNA (siRNA) attenuated the poly(I:C)-induced growth inhibition and apoptosis in SK-N-AS cellsTo confirm TLR3 is directly involved in the ... by WST-1 cellproliferation assay, flow cytometry analysis, and immunoblot analysis. Blockade of TLR3 signaling was achievedusing TLR3 neutralizing antibody, small interference RNA, and 2-aminopurine...
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Báo cáo y học: "Levamizole enhances immune responsiveness to intra-dermal and intra-muscular hepatitis B vaccination in chronic hemodialysis patients" pps
... showed that Levamisole increases both serum anti-body conversion rate and the duration that the antibodytiter is maintained. Kayatas [26] in another study reported the effect of Levamisole on the ... eliminationhalf-life of Levamisole is between 3–4 hours. Levamisole is extensively metabolized by the liver in humans and the metabolites excreted mainly by the kidneys (70% over 3days). The elimination half-life ... causes (includes: Alport syndrome in 1 case, Autosomal dominant polycystic disease in 1 case, Nephrolithiasis in 1 case and obstructive uropathy in 1 case).Publish with BioMed Central and every scientist...
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Báo cáo y học: "Use of a highly sensitive strand-specific quantitative PCR to identify abortive replication in the mouse model of respiratory syncytial virus disease" pptx
... analysis and interpretation of data, EJM, MW and CL participated in the design of the study and analysis and interpretation of data. HB conceived of the study,participated in its design and ... treated and untreated RSV infected mice. This sugg ests that the amount of new genome synthesised following infection is only a small fraction of that dosed initially and that measuring positive ... animals. A key question in this model is the fate of the administered virus. Is replication really being measured or is the model measuring the survival of the virus overtime? To answer these questions...
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Báo cáo y học: "Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice" docx
... nonbiomechanical link between obesity and osteoarthritis. Numerous proinflammatory cytokines that are secreted from hypertrophic abdominal adiposetissue (that is, adipokines or cytokines such as leptin,TNFα, ... fatdisappeared in the multivariate analysis that includeddiet, percentage body fat, and knee osteoarthritis score,indicating that neither diet or percentage body fat wasindependently related to the thermal ... minutes.Statistical analysisWe statistically analyzed differences due to diet and vari-ation in dietary obesity (that is, low gainer (LG) vs. highgainer (HG)) using a hierarchical analysis...
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Báo cáo y học: " Initial distribution volume of glucose can be approximated using a conventional glucose analyzer in the intensive care unit" pot
... adrenaline.bInsulin: continuous insulin infusion.Critical Care April 2005 Vol 9 No 2 Ishihara et al.R149IDVG is above 140 ml/kg and apparently low IDVG is less than100 ml/kg in the presence ... volumedeterminations during their stay in the ICU, the present studyconsidered only the first IDVG measurement in each patientduring their stay in the ICU. We included 40 surgical patientswho ... point-of-care testing to assess fluidvolume.Competing interests The author(s) declare that they have no competing interests.Authors' contributionsHI designed the study, performed statistical...
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