Báo cáo y học: "is enough oxygen too much" pot
Báo cáo y học: "is enough oxygen too much" pot
... induces systemic hypoxemia. During embryonic development, systemic oxygenation in the fetus is severely hypoxic by comparison to the adult.While severe hypoxia can threaten survival at any stage ... activated by hypoxia. AMPK preserves energy substrate supply by up-regulating glycolysis and fatty acid oxidation [5]. AMPK also regulates other biological processes.Interestingly, O2 acts ... tissue oxygenation in critically ill patients. While the conse-quences of oxygen deprivation are well known, we also know that excessive oxygenation creates new problems because hyperoxia...
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Báo cáo y học: "Is smaller high enough? Another piece in the puzzle of stress, strain, size, and systems" pdf
... present study, what is very probably a ‘false’ PEEPreduction (obviously triggered by the increase in thePaO2/FiO2[arterial partial pressure of oxygen/ fraction ofinspired oxygen] ratio ... anegligible level. Ideally, however, one venous double-lumencannula would ensure the vascular access, and a small pumpthat is very easy to handle may be integrated into the systemas a single-use ... assist in patients with acute respiratory dis-tress syndrome: a prospective pilot study. Crit Care 2009, 13:R10.2. Brower RG, Lanken PN, MacIntyre N, Matthay MA, Morris A,Ancukiewicz M, Schoenfeld...
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Báo cáo y học: "Is Obesity Associated with an Increased Risk for Airway Hyperresponsiveness and Development of Asthma" pdf
... respectively.12Biological PlausibilityTo establish causality between obesity, asthma, and BHR,plausible biological mechanisms must be proved tosupport this hypothesis. Obesity may directly affectindividuals ... Obesity and Asthma 5745. Jarvis D, Chinn S, Potts J, et al. Association of body mass indexwith respiratory symptoms and atopy: results from the EuropeanCommunity Respiratory Health Survey. Clin ... andImmunology, Department of Internal Medicine; and Mary Cheang:Department of Community Health Sciences, University of Manitoba,Winnipeg, MB.This study was supported by a grant from Respiratory Research,...
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Báo cáo y học: "Is there a dysfunction in the visual system of depressed patients" pptx
... 1Laboratory of Psychophysiology, 3rd Department of Psychiatry, Aristotle University of Thesssaloniki, Greece and 2Laboratory of Clinical Neurophysiology, 1st Department of Neurology, Aristotle ... respond tosleep deprivation, especially in combination to light ther-apy. Additionally, there is a direct connection of thehypothalamus with the retina (retinohypothalamic tract)and some authors ... of the symptomatology.Psychophysiological MethodsIt included:1. Electro-oculogram (EOG)which is a method with which one can study the electricaland metabolic activity of the outer layers of...
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Báo cáo y học: "Is closer linkage between systemic lupus erythematosus and anti-double-stranded DNA antibodies a desirable and attainable goal" ppsx
... antibody assays forSLE, while focusing on the organ specificity of anti-dsDNAantibody-mediated injury.Anti-dsDNA antibodies and lupuspathophysiologyAnti-dsDNA antibodies and SLE pathophysiology ... coincidewith anti-dsDNA antibody detection. Monthly increases inanti-dsDNA antibody levels (Farr assay) to guidepreventive therapy in European lupus patients significantlyreduced the number of relapses ... relapses in systemic lupus erythematosus.Lancet 1995, 345:1595-1599.22. Swaak AJ, Smeenk RJ: Following the disease course in sys-temic lupus erythematosus: are serologic variables of anyuse? J...
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Báo cáo y học: "Is there an association between anti-TNF monoclonal antibody therapy in rheumatoid arthritis and risk of malignancy and serious infection" ppt
... anCommentaryIs there an association between anti-TNF monoclonal antibodytherapy in rheumatoid arthritis and risk of malignancy andserious infection? Commentary on the meta-analysis byBongartz ... Watson K, Lunt M, Hyrich KL, British Society forRheumatology Biologics Register Control Centre Consortium,Silman AJ, Symmons DPM, on behalf of the British Society forRheumatology Biologics Register: ... Matteson EL,Montori V: Anti-TNF antibody therapy in rheumatoid arthritisand the risk of serious infections and malignancies: system-atic review and meta-analysis of rare harmful effects in ran-domized...
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Báo cáo y học: "Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus" ppsx
... size.This hypothesis, however, is supported by a very recent articleby Clancy et al. [35] showing that maternal autoantibodiesmay bind apoptotic cardiomyocytes and promote inflammationthereby contributing ... time of the studyPatient characteristicsInfiltrate No. Gender Age A C R Prednisone Hydroxychloroquine Azathio prine Autoantibody MED (years)1234567891011(mg/day) (mg/day) (mg/day)specificities(J/cm2)+ ... pro-inflammatory cytokines[17,18]. In this study, we analysed whether apoptotic keratino-cytes in patients with SLE, as induced by a single dose ofUVB, are cleared with delay and/or in an inflammatory...
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Báo cáo y học: "Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus" pot
... in fibroblast-like synoviocytes does not require p53Xin You, David L Boyle, Deepa Hammaker and Gary S FiresteinDivision of Rheumatology, Allergy and Immunology, University of California at ... orempty vector. p53 and p21 expression were then determined byWestern blot analysis. Apoptosis was assayed by ELISA tomeasure histone release and caspase-3 activation, or by trypanblue dye exclusion ... an especially interesting target because itrapidly induces apoptosis in cultured synoviocytes [5]. PUMAis a Bcl-2 homology 3 (BH3)-only pro-apoptotic Bcl-2 familymember recently identified...
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Báo cáo y học: "Is fibromyalgia a cardiovascular disease? A comment on Martinez-Lavin’s review ‘Stress, the stress response system, and fibromyalgia’" ppsx
... hypothesis but,rather, a group of evidence-based central nervous system(CNS)-centered physiopathogenesis hypotheses for FMS. Itconstitutes the only model capable of explaining the majorityof ... http://arthritis-research.com/content/9/5/404Fibromyalgia syndrome (FMS) is a mysterious condition withuncertain physiopathogenesis. Despite its hermeneuticproblems, FMS and related afflictions are responsible for themajority of family medicine ... probably a close relationshipbetween FMS and related diseases and cardiovascularalterations, especially dysautonomia. The pattern, as notedalso by Martinez-Lavin, involves not only sympathetic...
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Báo cáo y học: " Is interleukin-1 a good target for therapeutic intervention in intervertebral disc degeneration: lessons from the osteoarthritic experience" pdf
... work presented by Freemont’s group [1] has contri-buted greatly to our understanding of disc remodeling indegenerative IVD, notably the role of pro-inflammatorycytokines. They compare the expression ... plays a key role in disc degeneration and could be a validtarget for inhibiting this process. IL-1 receptor antagonist (IL-1ra)might be a good candidate to inhibit IL-1 activity. However, manyquestions ... tendency fordecreased synthesis of TNF RI was even observed inherniated and degenerated human IVDs compared to non-degenerated samples. These results are very importantbecause they suggest...
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