Báo cáo y học: "Burns: learning from the past in order to be fit for the future" pps

Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&

... for citation purposes)Child and Adolescent Psychiatry and Mental HealthOpen AccessResearchDoes switching from oral extended-release methylphenidate to the methylphenidate transdermal system ... AbstractBackground: To evaluate health-related quality of life (HRQL) and medication satisfaction after switching from a stable doseof oral extended-release methylphenidate (ER-MPH) to methylphenidate transdermal ... combined into the "agreed" category.MTS = methylphenidate transdermal system; ITT = intent to treat, MSS = Medication Satisfaction Survey. Child and Adolescent Psychiatry and Mental...

Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"

... and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis Jeffrey R Curtis1,#, John W Baddley1,2, Shuo Yang1, ... corresponds to the article as it appeared upon acceptance. Copyedited and fully formatted PDF and full text (HTML) versions will be made available soon. Derivation and preliminary validation of an administrative ... and specificity, unlike PPV and NPV, should be less dependent on the prevalence in the population, and more reflective of the test itself, lessening the impact of any unique features of the...

Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"

... β-glucosidases in the intestine and can be adminis-tered orally [27]. Therefore, the aim of the present study was to evaluate the inhibitory effect of some thioglycosides synthesized in our ... Paper Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes Francisco Castaneda1, Antje Burse2, Wilhelm Boland2, Rolf ... laboratory on human hSGLT1 and hSGLT2 as a potential therapeutic alternative for the control of hyperglycemia, particularly for people with diabetes. We chose to analyze the inhibitory effect of...

Báo cáo y học: "Capturing real-life patient care in psoriatic arthritis and its risks: the challenge of analysing registry data" docx

... perceivable in this study: the authors have adopted the methodology of looking at all treatment terminations and thenat only those terminations for the reason of ineffectiveness and terminated for the ... withdrawal. In summary, the study by Saad and colleagues gives usimportant insights into daily-life use of TNF inhibitors in PsA, adisease that too often is secondary to RA in the scientific and clinical ... perceptions of rheumatologists. The authors dealeffectively with the challenges posed by the type and origin of their data. Although toxicity and effectiveness analyses seemto favour etanercept and...

Báo cáo y học: " Bronchoalveoloar lavage fluid cytokines and chemokines as markers and predictors for the outcome of interstitial lung disease in systemic sclerosis patients" pps

... disease progress and the pathogenic mechanisms present in SSc-ILD. The role of chemokines and cytokines as markers reflecting disease severity and predicting outcome in SSc-related lung disease has not ... frequentmanifestation of systemic sclerosis (SSc), and cytokines cancontribute to the disease pathology. The aim of the current studywas to identify specific changes in cytokine levels that may serve as disease ... players in the disease process and potential therapeutic targets of SSc-related lung disease. Sys-temic sclerosis is a rare disease, and most studies analyzingBALF cytokines have included only...

Báo cáo y học: "Value of anti-infective chemoprophylaxis in primary systemic vasculitis: what is the evidence" pdf

... drawn.ReviewValue of anti-infective chemoprophylaxis in primary systemic vasculitis: what is the evidence?Frank Moosig, Julia U Holle and Wolfgang L GrossDepartment of Rheumatology, University Hospital of ... campath-1H.Pneumocystis jiroveci The risk of PCP is especially high in patients with SVVundergoing induction therapy. Without using prophylaxis the incidence of PCP is up to 20% [26] and many fatalities ... [78].ConclusionInfections significantly contribute to morbidity and mortality in PSV patients. There are three ways of targeting this problem:recognising and minimising risk factors, implementingprophylaxis...

Báo cáo y học: "Variety of transversus thoracis muscle in relation to the internal thoracic artery: an autopsy study of 120 subjects" docx

... Variety of transversus thoracis muscle in relation to the internal thoracic artery: an autopsy study of 120 subjects. Journal of Cardiothoracic Surgery 2011 6:11.Jelev et al. Journal of Cardiothoracic ... This study provides detailed basic information on the variety of the transversus thoracic muscle. Italso defines the range of the clearly visible, uncovered by the muscle part of the internal thoracic ... anatomy of the anterior thoracic wall. It describes the varie ty of the transversus thoracis muscle and its relation to the ITA. A completemuscular layer of significant size predominantly coversthe...

Báo cáo y học: "A meta-analysis of CAG (cytarabine, aclarubicin, G-CSF) regimen for the treatment of 1029 patients with acute myeloid leukemia and myelodysplastic syndrome" ppsx

... LY, He Q, Li X: Efficacy of induction chemotherapy for patients with high-risk myelodysplastic syndrome (MDS) or MDS-transformed acute myeloid leukemia with CHG regimen and its comparison with ... (CAG) has been widely used in China and Japan for treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). We searched literature on CAG between 1995 and 2010 and performed ... evaluate its efficacy and safety in comparison with the current standard treatment. Keywords acute myeloid leukemia; myelodysplastic syndrome; CAG; aclarubicin; meta-analysis Figure 3 ...

Báo cáo y học: "Visual impairment from fibrous dysplasia in a middle-aged African man: a case report" pptx

... impairment from fibrous dysplasia in a middle-aged African man: a case reportCharles O Bekibele1, Olubayo A Fasola2, Vickie N Okojie2, Opeyemi O Komolafe*1, Olayiwola A Oluwasola3, ... Judekenny2003@yahoo.com; Ayotunde I Ajaiyeoba - Ajaiyeoba@hotmail.com; Aderonke M Baiyeroju - baiyeroju@yahoo.com* Corresponding author AbstractIntroduction: Fibrous dysplasia is a benign ... Cob150@yahoo.com; Olubayo A Fasola - aolubayofasola@yahoo.com; Vickie N Okojie - vaokojie@yahoo.com; Opeyemi O Komolafe* - kopeyemi@yahoo.co.uk; Olayiwola A Oluwasola - oluwasol@yahoo.com; Jude K...

Báo cáo y học: " Augmentation of arginase 1 expression by exposure to air pollution exacerbates the airways " ppt

... Mol Biol 2 010 , 42:3-8.doi :10 .11 86 /14 65-99 21- 12 -19 Cite this article as: North et al.: Augmentation of arginase 1 expression by exposure to air pollution exacerbates the airways hyperresponsiveness ... Respiratory Research 2 011 , 12 :19 http://respiratory-research.com/content /12 /1/ 19Page 8 of 14 induced exacerbations of respiratory symptoms. In thisstudy we demonstrated further augmentation of arginase activity ... Research 2 011 , 12 :19 http://respiratory-research.com/content /12 /1/ 19Page 2 of 14 Facility, as previously described [16 ]. Goat anti -arginase 1 primary (sc -18 3 51) and donkey anti-goat secondary(sc-2042)...

Báo cáo y học: " Level and course of FEV1 in relation to polymorphisms in NFE2L2 and KEAP1 in the general population" pps

... variations in NFE2L2 or KEAP1 in relation to the level of FEV1. Yet the effect of rs11085735 in KEAP1 was significant only in never smok-ers, while the effect of rs2364723 and haplotype C in NFE2L2 ... bothcohorts).SNPs in NFE2L2 and KEAP1 and course of FEV1We did not observe any significant effect of SNPs in NFE2L2 and/ or KEAP1 on the course of FEV1 in either of the cohorts nor in the pooled ... in NFE2L2 and KEAP1 which affect the level of FEV1 in the general population. It additionally showsthat NFE2L2 and KEAP1 variations are unlikely to play a role in the longitudinal course of...

Báo cáo y học: "Comprehensive evaluation of genetic variation in S100A7 suggests an association with the occurrence of allergic rhinitis" pptx

... exclusively in the European and not in the Yoruban, Chinese or Japanese population samples of the HapMap project. Comparing this position in the humangenome with the corresponding position in the genome of ... individuals with ongoing allergic rhinitis, suggesting a role for S100A7 in allergic airway inflammation. The aims of this study wereto describe genetic variation in S100A7 and search for associations ... group. The analysis of this SNP wasrepeated using the Taqman platform. Concordance wasfound in 99.6% of the comparisons with only two out of 550 comparisons being discordant between the Taqmanand...

Báo cáo y học: " Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment" pot

... AccessResearch Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitmentHiroshi ... epithelial cells (HBEC)enhances the synthesis and release of a variety of pro-inflammatory cytokines and that supernatants from theseco-cultures instilled into rabbit lungs induces a systemicinflammatory ... cells aredirectly exposed to inhaled atmospheric particles thesesmall particles are phagocytized by both cells [10,12].Both cell types can synthesize a variety of pro-inflamma-tory cytokines...

Báo cáo y học: "Recently published papers: Sugar, soap and statins – an unlikely recipe for the critically ill" pdf

... than the first few days of the illness,although they proposed no reason for the observed increasein mortality in the group treated for fewer than 3 days [5].What is clear is that hypoglycaemia ... investigators have noticed an increase inhypoglycaemic events, similar to those reported by van denBerghe and colleagues. They therefore set out to identify the factors that may make this such a common ... ofdialysis) and incidence of hyperbilirubinaemia. The investigators suggested that, for the protective effect ofstrict normoglycaemia to be realized, the therapy must beestablished for longer than...

Báo cáo y học: "Burns: learning from the past in order to be fit for the future" pps

... dressings or early excision and grafting is the key to avoid burn wound infection and its extension to systemic infection [8-10].  e timing and extent of surgery may vary, as well as the method ... of these were due to acute respiratory distress syndrome [1]. Although the methods used for the management of acute respiratory distress syndrome have changed drama-ti cally over the past ... process to a more critical care approach using more physiologic endpoints such as urinary output and other measurements, so the trend in burn resuscitation is shifting the focus from ﬂ uid formulas...

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