... resistance is extremely low. For instance, the emergence of ADV resistant mutation, N236T, was only 1.8 and 3.9% in patients who received 2 and 3 years of this treatment, respectively [17, ... Zhou Y. Efficacy and safety of lamivudine treatment for chronic hepatitis B in pregnancy. World J Gastroenterol 2003; 10:910-912. 33. Quan DJ, Peters MG. Antiviral therapy: nucleotide and nucleoside ... administration, duration and efficacy of the treatment, frequency of drug resistance, and cost do exist in these three drugs. Thus, an HBV treatment should be tailored based on the type of chronic HBV...