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structure and function of a dogs eye

Báo cáo khoa học: Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein doc

Báo cáo khoa học: Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein doc

Báo cáo khoa học

... shared secondary structure characteristics of transthyretins and TLPs are indi-cated above the alignment: motifs A –C’ are indicated with straight lines and are labelled; b-strands are indicated ... 0Loktanella vestfoldensis SKA53 Proteobacteria, Alphaproteobacteria 2 0Roseovarius sp. HTCC2601 Proteobacteria, Alphaproteobacteria 2 0Ralstonia eutropha H16 Proteobacteria, Betaproteobacteria ... colonizevarious animals. Uric acid is secreted on the surface of mucosal epithelial tissues of all animals as part of theinnate immune system [47] and is also thought to actas a microbicidal agent...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc

Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc

Báo cáo khoa học

... to pain and was effective inalleviating chronic pain and accelerating functional recoveryin an animal model of neuropathy. These data are inagreement with an important role of nAChRs in painperception, ... interfaces within neuronal nAChR subunitcombinations (compare Fig. 2A C)4.Sofar ,a- conotoxinsselectively targeting mammalian a3 b2 (a- MII, a- GIC) a6 b2 (a- MII, a- PIA), a3 b4 (a- AuIB) and a7 (a- ImI) ... investigation and understanding of their structure- activity relationships,may start to provide a rational way to develop additionalpharmacological tools for the elucidation of nAChR structure and function. Ó...
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Báo cáo khóa học: S-(2,3-Dichlorotriazinyl)glutathione A new affinity label for probing the structure and function of glutathione transferases potx

Báo cáo khóa học: S-(2,3-Dichlorotriazinyl)glutathione A new affinity label for probing the structure and function of glutathione transferases potx

Báo cáo khoa học

... Zeta, Phi, Tau and O mega [3,4,9]. Whereas Zeta, Theta and Omega classes of GSTs are found in plants and animals, the large Phi and Tau classes a re unique to plants [9]. In maize ( Zea m ays L),42 ... fractional residual activity of thepartial active enzyme intermediate, and kfast and kslowarethe rate constants for the slow a nd fast phase of the reaction.Analysis was performed using theGRAFIT(ErithacusSoftware ... probing the structure and function of glutathione transferasesGeorgia A. Kotzia and Nikolaos E. LabrouLaboratory of Enzyme Technology, Department of Agricultural Biotechnology, Agricultural University...
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Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf

Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf

Báo cáo khoa học

... complexthan in T cells, with several peaks of nuclease hyper-sensitivity [85]. Mast cells express GATA-2 as well asNFAT and AP-1, and GATA-2 initiates the formation of an additional discrete GATA-2 ... typically recruitHATs such as SAGA and NuA3, which mainly acety-late histone H3, and NuA4 which acetylates histone H4on K5, K8 and K12. This cascade of events leads torecruitment of transcription ... H4-K16,the NuA4 group of HATs are essential for H4-K5, K8 and K12 acetylation [136–138]. In yeast, this group ismade up of NuA4 and Piccolo NuA4 which both uti-lize Esa1 as the HAT, and Esa1 was found...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx

Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx

Báo cáo khoa học

... Science Institute, Saitama, Japan2 JST, CREST, Kawaguchi, Saitama, Japan3 Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, Japan4 Faculty of Science and Technology, ... co-immunoprecipitation.Primary cultures, transfection and imaging of hippocampal and cerebellar neuronsHippocampal and cerebellar dissociated primary cultureswere prepared from ICR mice (Nippon SLC, Hamamatsu,J. ... circuits, and also may provide a clue to theunderstanding of some MAP2-associated neurodegen-erative and psychiatric disorders [16,17].Materials and methodsAnimalsMice (ICR) were purchased from...
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Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx

Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx

Điện - Điện tử

... spp.1Stylatula elongata1Xenia spp.1Actinaria (sea anemones) Anemonia viridis1Anthopleura elegantissimaCorynactis californica1Metridium senileZoanthidea Palythoa variabilisScleractinia (hard ... Lepas pectinataCopepoda Centropages typicusStylasterina (Hydrozoan hard corals) Stylaster californicus1Octocorallia (soft corals & sea pens) Paracyanthus stearnsi1Sansibia spp.1Stylatula ... Data on rmaxfor a wide variety of organisms, from unicellular eukaryotes to invertebrates and vertebrates, have been compiled and analyzed by Savage et al.(2004b). Thesedata give a slope of...
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Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx

Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx

Báo cáo khoa học

... relationship and tertiary structure. Plant APs have been distributed among families A1 , A3 , A1 1 and A1 2 of clan AA, and family A2 2 of clanAD. The majority of plant APs belongs to the A1 family,together ... Molecular and biochemical characterisation of two asparticproteinases TcAP1 and TcAP2 from Theobroma cacao seeds.Planta 215, 754–762.12. Park, H., Yamanaka, N., Mikkonen, A. , Kusakabe, I. &Kobayashi, ... phytepsin was purified from barley (H. vulgare)(acces-sion number: X56136); AtAsp1, AtAsp2 and AtAsp3 are A. thalianaaspartic proteinases (accession numbers: U51036, AY070453 and AF076243, respectively);...
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf

Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf

Báo cáo khoa học

... the structure and dynamics of each protein, and present a comparison of s bwAFP and TmAFPwitheachotherandwithproteinsthathaveasimilar fold. Structure of sbwAFP and TmAFPThe structure of sbwAFP ... growth.ConclusionAnalysis of the structure and examination of the i ce-bindingbehaviour and point mutants of s bwAFP and TmAFPprovides an explanation for their hyperactivity compared tothe previously characterized ... the case of one sbwAFP isoform,named CfAFP-501, a detailed e xamination of t he structure and function was undertaken [57]. An overall match of 66%amino-acid identity was observed, with an insert...
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Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf

Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf

Báo cáo khoa học

... 389–392; and b7, 409–412) form a b-sheet with three antiparallel strands (1, 2 and 7) and strand 6, which is parallel to strand 2. b-Strands arelocated between the four a- helices (a1 , 278–294; a2 ,305–313; ... signal of the preceding amino acid, correlating the amide HN and the Ca signals, correlating the amide HN and the Ca signal of the preceding amino acid, correlating the amide NH withthe Ca and ... protein backbone, and formore than 78% of the side chain atoms.The main set of backbone u and w dihedral angles wascalculated from the chemical shift values of backboneatoms13Ca,13Cb,13C¢,1Ha,1HN,...
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Báo cáo khoa học: Staphylococcus aureus elongation factor G – structure and analysis of a target for fusidic acid pdf

Báo cáo khoa học: Staphylococcus aureus elongation factor G – structure and analysis of a target for fusidic acid pdf

Báo cáo khoa học

... The Authors Journal compilation ª 2010 FEBSStaphylococcus aureus elongation factor G – structure and analysis of a target for fusidic acidYang Chen, Ravi Kiran Koripella, Suparna Sanyal and Maria ... Helgstrand M, Mandava CS, Mulder FA, Liljas A, Sanyal S & Akke M (2007) The ribosomal stalk bindsto translation factors IF2, EF-Tu, EF-G and RF3 via a conserved region of the L12 C-terminal ... 4714177E-mail: maria.selmer@icm.uu.seDatabaseThe atomic coordinates and observed structure factors are available in the ProteinData Bank database under the accessionnumber 2XEX(Received 22 April...
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Báo cáo khoa học: Structure and function of KH domains docx

Báo cáo khoa học: Structure and function of KH domains docx

Báo cáo khoa học

... b1-strand and b2-strand are adjacent and parallel to each other, and the b¢-strand is adja-cent and antiparallel to the b1-strand (Fig. 1). Thelength and sequence of the variable loop are differentin ... RNA. The tandem KH1–KH2 domains of NusA recognizeRNA ligand 5¢-GAACUCAAUAG. (A) The KH1–KH2 domains of NusA bound to cognate RNA ligand (Protein Data Bank entry 2ASB). TheRNA–protein contact ... orderb1, b¢ and b2. The b1-strand and b2-strand are parallelto each other, and the b¢-strand is antiparallel to both(Fig. 1). This all-antiparallel arrangement of strandsdistinguishes the type...
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Báo cáo khoa học: Structure and function of N-acetylglucosamine kinase Identification of two active site cysteines pptx

Báo cáo khoa học: Structure and function of N-acetylglucosamine kinase Identification of two active site cysteines pptx

Báo cáo khoa học

... 5¢-GGAACAGGCTCCAACAGTAGGCTTATCAACCCTGATGGC143S 5¢-GATGGCTCCGAGAGTGGCAGTGGAGGCTGGGGC211S 5¢-CCCATTTGTATAGGGACTTTGATAAAAGTAAGTTTGCTGGATTTTGCCAGAAAATTGCC217S 5¢-GCTGGATTTAGTCAGAAAATTGCAGAAGGTGCACATCAGGGC268S ... presumably with different regulation.GlcNAc kinase has been cloned from man [8] and mouse[9]. Like N-acetylgalactosamine kinase [10] and N-acetyl-mannosamine kinase, as a part of the bifunctional ... generation of GlcNAc kinasecysteine mutants by site-directed mutagenesis. Mismatches with thetemplate are underlined.Name SequenceC45S 5¢-GGCACAGACCAGAGTGTGGAGAGGATCA ATGAGC131S 5¢-GGAACAGGCTCCAACAGTAGGCTTATCAACCCTGATGGC143S...
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Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot

Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot

Báo cáo khoa học

... cal-orimetry, of bovine b-andj-casein, recombinant human a- ,b-andc-synuclein, together with the A3 0P and A5 3T mu-tants of a- synuclein associated with familial cases of Par-kinson's disease, and ... the A3 0P and A5 3T mutants of a- synuclein that cause f amilial c ases of Parkinson's disease.Unfortunately the quality of s ome of these syn uclein ROAspectra i s generally not as good as ... temperature backscatteredRaman a nd ROA spectra of bovine b-casein (top pair) and j-casein (bottom p air) at pH 7.0. Overall, the ROA spectraare very much a like, demonstrating that the basic...
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Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt

Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt

Báo cáo khoa học

... Ile-Glu-Ala-Arg-p-nitro-anilide (IEARpNA) [31]. ProHP8Xalacked IEARaseactivity, but after the zymogen was activated by factorXa, IEARase activity increased significantly above that of factor Xa alone, which could also ... thesubstrate (Fig. 6B). These results indicated that factorXa cleaved and activated proHP8Xa.When activated HP8Xawas mixed with proSpa¨tzle- 1A, the 38 kDa pro-Spa¨tzle band disappeared, and ... (2004)Beta-1,3-glucan recognition protein-2 (betaGRP-2)fromManduca sexta; an acute-phase protein that bindsbeta-1,3-glucan and lipoteichoic acid to aggregate fungi and bacteria and stimulate prophenoloxidase...
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Báo cáo Y học: Structure, mechanism and function of prenyltransferases docx

Báo cáo Y học: Structure, mechanism and function of prenyltransferases docx

Báo cáo khoa học

... &Glomset, J .A. (1994) Rab geranylgeranyl transferase catalyzesthe geranylgeranylation of adjacent cysteines in the samllGTPases Rab 1A, Rab 3A, and Rab 5A. Proc. Natl. Acad. Sci. USA 91, 11963–11967.89. ... FTase incomplex with FPP [38] as well as the structure of the ternarycomplex containing an inactive FPP analogue and a CaaXpeptide substrate [39]. Many features of the apo-FTase structure are ... Synthesis and characterization of aza analog inhibitors of squalene and geranylgeranyl diphosphate synthases. J. Org. Chem. 57, 3444–3449.75. Sagami, H., Korenaga, T., Ogura, K., Steiger, A. , Pyun,...
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