... lifestyle and dietary habits, but is not a signifi-cant independent susceptibility factor. The p53 tumor suppressor pathway is well-known to be crucial in maintaining genomic in- tegrity and ... esophageal cancer in south africa. Cancer Genet Cytogenet 2003;140:23-30. 24 Hong Y, Miao X, Zhang X, Ding F, Luo A, Guo Y, Tan W, Liu Z, Lin D: The role of p53 and mdm2 polymorphisms in the risk of ... ZW, Taylor PR, Dawsey SM, Qiao YL: Polymorphic variation of cyp1a1 is associated with the risk of gastric cardia cancer: A prospective case-cohort study of cytochrome p-450 1a1 and gst enzymes....