... and protein dynamics (Eur. J. Biochem. 269) 3111 MINIREVIEW Barrier passage and protein dynamics in enzymatically catalyzed reactions Dimitri Antoniou1, Stavros Caratzoulas1,*, C. Kalyanaraman1, ... Cha, Y. , Jonsson, T., Grant, K.L. & Klinman, J.P.(1992) Role of internal thermodynamics in determining hydrogentunneling in enzyme -catalyzed hydrogen transfer reactions. Bio-chemistry 31, ... allowdetailed study of the in uence of protein composition on protein dynamics, and how dynamics relates to kineticsof catalysis.Our analysis began with the 2.1-A˚crystal structure ofPlapp and coworkers...