... l-lysine, l-serine, b-alanine, taurine, sarcosine,dimethylglycine, glycine betaine, trimethylamine N-oxide, and cytidine 2¢-3¢ cyclic monophosphate were also obtainedfrom Sigma. These and other ... advances in understanding the effect of osmolytes on protein stability, folding and the activity of proteins and enzymes, the relationshipbetween protein stabilization by osmolytes and its con-sequent ... that protein stability and activity are not largelycoupled in the presence of osmolytes. However, proteinstability and activity have a linear correlation in the presence of methylamines and sugar...