USMLE ROAD MAP BIOCHEMISTRY – PART 2 docx

... cyanosis.Chapter 2: Protein Structure and Function 17NPO 2 in tissuesPO 2 in lungs100806040 20 00 20 40 60 80 100 120 140Percent O 2 saturationPO 2 (mm Hg)MyoglobinHemoglobinFigure 2 5 . Oxygen ... Biochemistry NPeptide substrateIOHCH 2 OCNHChymotrypsinIIOHH111 2 2 2 IIIOHCH 2 OCOHOCH 2 OH 2 NH 2 NCFigure 3 2 . Reaction mechanism of chymotrypsin as an example of covalent catal-ysis. ... lethal soon after birth.14 USMLE Road Map: Biochemistry NCLINICALCORRELATIONCLINICALCORRELATIONCLINICALCORRELATION34 USMLE Road Map: Biochemistry NVmaxVi1 2 Vmax00[S]Positive...

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USMLE ROAD MAP BIOCHEMISTRY – PART 3 docx

... composition.40 USMLE Road Map: Biochemistry NSteroid nucleusCH3HOABCDCH3CH3CH 2 CH 2 CH 2 CH3CH3CHCH 23 22 24 27 26 25 21 2 1345678141516 20 171119109 12 1813Figure 4–3 . Structure ... 43NOHCHCOHHOCHHCOHHCOH6411 2 3456 2 3CH 2 OHCH 2 OHHHOHOCHCOH 2 56CH 2 OHABβ-D-GlucoseOHHHOHHHO1CH 2 OH3HOCH4HCOH65 2 34HOH 2 COHHOHCH 2 OHHHOβ-D-FructoseCH 2 OHHHOHCSucroseGlycogenα-1, ... transport coupled to ATP hydrolysis48 USMLE Road Map: Biochemistry N 2. The fatty acids attached to the glycerol backbone also vary in length and struc-ture (Figure 4 2 ).a. Fatty acids that have no...

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USMLE ROAD MAP BIOCHEMISTRY – PART 10 docx

... regulation of,3 3–3 4catalysis mechanisms, 2 7 2 8, 28 fcatalytic of reactions by, 2 6 2 7, 27 fclinical problems/solutions,3 4–3 6classification, 2 5 2 6, 26 tcoenzymes and cofactors, 32, 33tcovalent ... (splicing),16 3–1 64, 163fstructure, 16 0–1 61transcription, 16 1–1 62, 162fexample of anticipation,193Tumor necrosis factor-α(TNF-α), 20 7Tumor-promoting phorbolesters, 20 5 2 06Tumor suppressors, 21 2 2 13, 21 2floss ... 1 92 Niemann-Pick disease, 2 4 2 5Nitrogen metabolismamino acid biosynthesis, 129 , 130f, 131famino acid catabolism, 12 6–1 29 , 127 fammonia metabolism, 123 , 124 fclinical problems/solutions,13 5–1 38,...

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USMLE ROAD MAP BIOCHEMISTRY – PART 1 ppsx

... otherwise. DOI: 10.1036/00714 420 57USING THE USMLE ROAD MAP SERIES FOR SUCCESSFUL REVIEWWhat is the Road Map Series?Short of having your own personal tutor, the USMLE Road Map Series is the best ... ion, OH – .H 2 O→←H++ OH – 1. This dissociation is reversible and is defined by the equilibrium constant, Keq.Keq=[H+][OH-][H 2 O]Ka=[H+][A-][HA] 2 USMLE Road Map: Biochemistry Nb. ... Biochemistry N0 123 456pH7891011Titrationof —NH3+Titrationof —COOH 12 1.5 2 1Equivalents of base added0.50pKaCOOHpH = pIpI = = = 6.0pKaNH3+pKaCOOH + pKaNH3+ 2 2.5 + 9.5 2 Figure 2 1 ....

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USMLE ROAD MAP BIOCHEMISTRY – PART 4 ppsx

... (glycogenolysis). 2. Glycogen stores serve as an easily mobilized source of glucose to providefor the short-term needs of the body.78 USMLE Road Map: Biochemistry NTable 6 2 . Regulators of ... to ribose5-phosphate (Figure 6–3 ).a. Ribose 5-phosphate provides the ribose and deoxyribose sugars found innucleotides.76 USMLE Road Map: Biochemistry NTable 6–1 . Energy yield in anaerobic ... steps.1. Carboxylation of pyruvate to oxaloacetate occurs in the mitochondria (Fig-ure 6–7 ). 82 USMLE Road Map: Biochemistry NF. Conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate represents...

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USMLE ROAD MAP BIOCHEMISTRY – PART 5 pot

... NAD++ FAD + GDP + Pi→ 3 CO 2 + 4 NADH + 4 H++ FADH 2 + GTP 2. One of the carbons of pyruvate is released as CO 2 during the formation ofacetyl CoA. 92 USMLE Road Map: Biochemistry NTHIAMINE ... portion of fructose to be excreted in the urine.86 USMLE Road Map: Biochemistry NCLINICALCORRELATIONCLINICALCORRELATION1 02 USMLE Road Map: Biochemistry N5. The answer is A. This patient exhibits ... heat. 2. Chemical agents (such as 2, 4-dinitrophenol) that are able to bind a protonand be soluble in the lipid bilayer can also act as uncoupling agents.98 USMLE Road Map: Biochemistry NTable 7–1 ....

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USMLE ROAD MAP BIOCHEMISTRY – PART 6 pot

... CoA(C16)CH3(CH 2 ) 12 βCH 2 αCH 2 COSCoAMyristoyl CoA(C14)CH3(CH 2 ) 12 COSCoA+CH3COSCoACH3(CH 2 ) 12 CH CH COS CoAFADNAD+H 2 OCoAC 12 C10C18C6C4Acetyl CoA (C2)Cycle ... PhosphateATPATPCO 2 CitrullineArgininosuccinatesynthetaseArgininosuccinateArgininosuccinatelyaseArginineAspartateAMP + PPiArginaseOrnithineUreaFumarate+ NH4+ 2 2 ADP + PiPiH 2 OCONH 2 H 2 NFigure 9 2 . The urea cycle. The enzymes that catalyze ... possibleproblems: – Hepatic dysfunction leading to decreased bile acid synthesis. – Severe ileal disease leading to malabsorption of bile salts. – Obstruction of the biliary tract.116 USMLE Road Map: Biochemistry NNo...

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USMLE ROAD MAP BIOCHEMISTRY – PART 8 pdf

... Single-stranded breaks 2. In this case, which repair mechanism is most likely defective?A. Base excision repairB. Mismatch repair164 USMLE Road Map: Biochemistry N 2. The tRNAs are 6 5–1 10 nucleotides ... (seeChapter 12) .1 62 USMLE Road Map: Biochemistry NRNA Pol IIHoloenzymeNon-templateDNA strandTemplateDNA strand TopoisomeraseNascent hnRNA5'3'SynthesisTopoisomeraseFigure 1 1–3 . The ... the A site.1 72 USMLE Road Map: Biochemistry NRelease ofempty tRNATranslocationPeptidyltransfer(n+1)(n)EF + GDP + PiAminoacyl-tRNAbindingTernarycomplexEFFigure 1 2 3 . Peptide elongation...

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USMLE ROAD MAP BIOCHEMISTRY – PART 9 ppt

... samedata.2pq = 2( 0. 02) (0.98) = 0.03 92 or 3.9%q =A1 25 00= 20 .0004 = 0. 02, and: p = 1- q = 1- 0. 02 = 0.98194 USMLE Road Map: Biochemistry NMalesA(p)A(p)a(q)a(q)AA(p 2 )Aa(pq)A(pq)aa(q 2 )FemalesFigure ... retardation.186 USMLE Road Map: Biochemistry NMaleFemaleAffectedUnaffectedDeceasedObligate carrierMarriage or matingConsanguinityProband 123 4 123 45 12 3 123 4567IIIIIIIV,,,,Figure 1 3–1 . ... influence of environmentq =A1400= 1 /20 = 0.05 and p = 1- q = 1- 0.05 = 0.95P =¢1 2 ≤¢1 2 ≤¢ 2 3≤A1 25 ,000=¢16≤¢1500≤=13000198 USMLE Road Map: Biochemistry N...

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Tài liệu Các mẫu từ tiếng Nhật thực dụng part 2 docx

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