Báo cáo khoa học: "Choosing the right combination therapy in severe community-acquired pneumonia" pdf

... prospective,randomized, double-blind trials confirm the benefit of combination therapy in pneumococcal disease, including aclear benefit of having a macrolide as part of the combination. For a disease ... of combination therapy in severe CAP, conducting prospective, randomized clinicaltrials including a large proportion of Pneumonia SeverityIndex of V patients should be a priority.Competing interests The ... by physicians in the study byMortensen et al. [10] is a clear indication that the therapeuticuncertainty in severe CAP is perceived by physicians at the ‘front line’. Indeed, other studies [18-20]...

Tài liệu Báo cáo khoa học: "Choosing the Word Most Typical in Context Using a Lexical Co-occurrence Network" ppt

... made by our program to the baseline of always choosing the most frequent synonym according to the training corpus. But what are the 'correct' responses? Ideally, they should be chosen ... word, connect it to all the words that sig- nificantly co-occur with it in the training corpus; 1 then, recursively connect these words to their significant co- occurring words up to some specified ... thesis, Columbia University. Golding, Andrew R. and Yves Schabes. 1996. Combin- ing trigram-based and feature-based methods for context- sensitive spelling correction. In Proceedings of the...

Báo cáo khoa học: "Do fluoroquinolones actually increase mortality in community-acquired pneumonia" pdf

... patientsincluded in our cohort. According to the clinical practiceguidelines published by the Infectious Diseases Society ofAmerica and the American Thoracic Society [4,9], the use ofthese antimicrobials ... andnowhere in the report presenting the results of the study [6]can we find separate information on the patients who weretreated with erythromycin and ceftriaxone (which would be the only guideline-concordant ... groups in administration within8 hours (59% versus 56%; P = 0.72).Third, Dr Agarwal criticizes the use of pipericillin–tazobactam aspart of the initial antimicrobial treatment in 25% of the patientsincluded...

Tài liệu Báo cáo khoa học: "Selecting the “Right” Number of Senses Based on Clustering Criterion Functions" pdf

... asinput the H 2 values generated from 1 deltaKand automatically determine the right value ofk, based on finding when the changes in H 2 as kincreases are no longer significant.2.1 PK1 The ... threshold. The graph of the P K1 scores shown in Figure 1 illustrates the dif-ficulty - the slope of these scores is nearly linear,and as such the threshold (as shown by the hori-zontal line) is ... similarity, the better the clustering.A large value indicates that the clusters have highinternal similarity, and are clearly separated fromeach other. Intuitively then, one solution to select-ing...

Báo cáo y học: "Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure" ppt

... analyses involvingonly the genes in the pathway in relation to the treatment. The main objective of this paper is to demonstrate the utility ofincorporating pathway network information in a pathwayenrichment ... chosenempirically in order to control for the selection of the pathwaywith the most significant genes (relative to the other genes in the system). The first terms in the products on the right- handside ... difference in the mean of differential expression of the genes in the pathway and that of the other genes in the sys-tem. Higher CF values indicate higher individual associationvalues for genes in the...

Tài liệu Báo cáo khoa học: "Extending the BLEU MT Evaluation Method with Frequency Weightings" pdf

... is the number of occurrences of the word wi in the document dj; – dfi is the number of documents in the cor-pus where the word wi occurs; – N is the total number of documents in the ... of the word in the whole corpus, including this particular text. In the second stage we carried out N-gram based MT evaluation, measuring Precision and Recall of N-grams in MT output using ... are increased by the value of the respective score (not just by 1, as in the baseline BLEU approach). The original matches used for BLEU and the weighted matches are both calculated. The...

Báo cáo khoa học: Enhancing the protein production levels in Escherichia coli with a strong promoter potx

... were then dilutedﬁve-fold in 1· NaCl ⁄ Piresulting in a ﬁnal urea concentra-tion of 0.2 m. Immediately after dilution, the initial proteinconcentration was determined using the bicinchoninic ... with the data obtained when analyzing the sameprotein in vitro. Because eGFP does affect the solubil-ity, the solubility class used in this case is the one witheGFP. As shown in Fig. 2, there ... under the control ofT7. On the other hand, protein I appears to be veryinsoluble even under the control of lacUV5.Although the fraction of soluble protein is veryinteresting, it is still the...

Báo cáo khoa học: "Relieving The Data Acquisition Bottleneck In Word Sense Disambiguation" ppt

... thereforesimilar contexts, which in a learning framework de-tract from the learning algorithm’s discriminatorypower.Upon examining the 29 polysemous nouns in the training and test sets, we observe ... the target word.3.1.1 Manually Annotated Training Data The manually-annotated training data is the SEN-SEVAL2 Lexical Sample training data for the En-glish task, (SV2LS Train).2This training ... . According to the manual sense grouping,senses 1 and 3 are similar, and indeed, upon inspec-tion of the context distributions, we ﬁnd the bulkof the senses’ instance examples in the SALAAM-tagged...

báo cáo khoa học: " Measuring the context of care in an Australian acute care hospital: a nurse survey" doc

... However, these findings are only preli-minary. The Canadian study reported differencesbetween the four hospitals for many context dimensions(combining all professions together), indicating the inherent ... between the twocanonical variates in the first function, then the secondfunction is calculated by maximising the remainingunexplained variance [20]. T he strength of the rela-tionship between the ... work in one setting maynot work in a different setting with different context.TheroleofcontexthasbeendefinedinthePARIHSframework (Promoting Action on Research in HealthServices), which hypothesised...

Tài liệu Báo cáo khoa học: Proteolytic processing regulates pathological accumulation in dentatorubral-pallidoluysian atrophy pdf

... pan-caspase inhibi-tor selectively increased the accumulation of the C-terminal fragment in the cytoplasm, which recapitu-lated the cytoplasmic inclusion seen in the DRPLAbrain. Taken together, these ... and also include nuclear inclusions in the DRPLA brains [2,26]. In the present study, the ATN1 antibody L55-2 labelled neuronal cytoplasmicand nuclear inclusions in the DRPLA brain. The bio-chemical ... fragmentscontaining the polyQ tract in COS-7 and Neuro2acells. ATN1 was processed into two C-terminal frag-ments that lost the nuclear localizing signal (NLS) in the N-terminal. One of the C-terminal...

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