Báo cáo y học: "Bench-to-bedside review: Therapeutic options and issues in the management of ventilator-associated bacterial pneumonia" ppt

... incidence, aetiology and diagnosis of VAP, and addresscurrent therapeutic options. ReviewBench-to-bedside review: Therapeutic options and issues in the management of ventilator-associated bacterial ... ventilated patients, the clinicaldiagnosis was correct in 62% of cases and therapeutic treatment plan was appropriate in only 33% of cases.Given the difficulty in diagnosing pneumonia in the ventilatedpatient ... by supine position and by upper airway and gastrointestinal intubation;aspiration in mechanically ventilated patients occurs around the outside of the endotracheal tube rather than through the lumen....

Báo cáo y học: "Low-concentration, continuous brachial plexus block in the management of Purple Glove Syndrome: a case report" pps

... veinresulting in disruption of the endothelial-intercellularjunctions and seepage of the drug into the interstitialspace [1]. Extravasation of the highly albumin-bound (70-90%) phenytoin increases the ... alleviate the vasospasm and the pain while preserving the motor function for the patient to perform active movements of the finger and hand.IntroductionIntravenous administration of phenytoin can ... immediate discon-tinuation of the infusion and removal of the intravenouscatheter [1]. The diagnosis of PGS is based on the characteristicclinical findings and a high index of suspicion when...

Báo cáo y học: " HIV-1 Accessory Protein Vpr: Relevance in the pathogenesis of HIV and potential for therapeutic interventio" ppsx

... epithe-lium [177]. In vivo, FGF-2 likely increases the invasion of inflammatory cells into renal tissue, leading to renalinjury. Interestingly, Vpr has been implicated in the development of ... may have varying effects on the HIV-1 LTR depending on the context of proinflamma-tory and anti-inflammatory signals, in addition to GRpathways. The interrelationship of Vpr functions and theirrelevance ... and another involvingenergy [39]. In summary, Vpr may use importin-a in anon-conventional, energy independent manner, but m ayalso use a yet undetermined mediator in the absence of importin-a...

Báo cáo y học: "Monoclonal Antibodies against Nucleophosmin Mutants: Potentials for the Detection of Acute Myeloid Leukemia" ppt

... were analyzed by IHC, using the 2G3 mAb. The cytoplasmic dislocation of NPM1 was ob-served in all 10 samples with NPM1 mutations, without staining in the cytoplasm of leukemic blasts in the negative ... Hospital of Chongqing Medical University (Chongqing, China) between 2008 and 2009. Informed consent was obtained from all patients, and the study was approved by the ethics committees of the participating ... of cytoplasmic dislocation of NPM1 by IHC has been performed using aspecific antibodies that bind both the NPM-wt and NPM-mA proteins. In IHC assay labeling with this kind of mAbs, the cyto-plasmic...

Báo cáo y học: "Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis" ppsx

... 118 min and 123 min,respectively. In both groups symptoms started with pain and swelling, predominantly symmetrical and in the small joints of the hands and feet. In the statistical analysis ... questionnaireinquiring about the initial symptoms as reported by the patient(type of initial joint symptoms, localization and distribution of initial joint symptoms, presence of morning stiffness). ... for the individualMCP and PIP joints of the hands at inclusion and at 2 and 4years follow-up, and are expressed as the mean with the 95%confidence interval (CI). The distribution and degree of...

Báo cáo y học: "Automatic versus manual pressure support reduction in the weaning of post-operative patients: a randomised controlled trial" pdf

... by 1 cmH2Oevery four respiratory cycles, if the patient's RR was less than 15per minute). The primary endpoint of the study was the duration of the weaning process. Secondary endpoints ... involved in the analysis and interpretation of the data and in drafting the manuscript.Acknowledgements The authors would like to thank all the physiotherapists and physicians who have taken care of ... groupsduring the first 180 minutes of the weaning process (Figure 6). The SpO2 was maintained above 95% in both groups during the study period. (p = 0.16). The PEEP value was maintained at about...

Báo cáo y học: "Spinal manipulative therapy versus Graston Technique in the treatment of non-specific thoracic spine pain: Design of a randomised controlled trial" potx

... for the entirestudy period and will be continually counselled by the research investigator regarding the importance of blind-ing. They will be trained in administration of informedconsent and ... Definition of non specific Thoracic spine pain [11]Definition of non specific Thoracic spine painMidline back pain – for the purposes of this trial, the pain will be bound by the lateral margins ... that the instru-ments are much like tuning forks as they reportedlyresonate in the clinician's hands allowing the clinician toisolate adhesions and restrictions, and treat them very pre-cisely....

Báo cáo y học: "Is smaller high enough? Another piece in the puzzle of stress, strain, size, and systems" pdf

... the concept of setting PEEP according to a table becomes evident, and in the present study, what is very probably a ‘false’ PEEPreduction (obviously triggered by the increase in the PaO2/FiO2[arterial ... areas,indicating sustained derecruitment of the lungs. Thisphenomenon has also been demonstrated in the clinicalsetting by Richard and colleagues [7] in ARDS patients whilereducing the tidal ... Ideally, however, one venous double-lumencannula would ensure the vascular access, and a small pumpthat is very easy to handle may be integrated into the systemas a single-use product, delivering...

Báo cáo y học: " Ventilator-induced endothelial activation and inflammation in the lung and distal organs" docx

... results indicate that venti-lator-induced changes of the immune response may occursimultaneously in the lung, liver and kidney, and imply thatrelease of inflammatory mediators into the circulation ... and cytokines or chemokines in distal organs.It has been hypothesized that the physical stress of MV acti-vates the sympathetic nervous system [19]. In this regard,Elenkov and colleagues and ... endothelialactivation and inflammation in mice without pre-existingpulmonary injury, both in the lung and distal organs.IntroductionCritically ill patients in the intensive care unit often...

Báo cáo khoa học: Accessory proteins functioning selectively and pleiotropically in the biosynthesis of [NiFe] hydrogenases in Thiocapsa roseopersicina docx

... obviously fundamentalroles in the formation of any [NiFe] hydrogenase. The physiological functions of the HynD, HupK and HypC1 and HypC2proteins were investigated in detail. The hynD gene of T. ... resulted in the identiﬁ-cation of one locus containing the hupK-hypC1DE accessorygenes and another one, where the hypC2 and hynD geneswere found. The organization of the accessory genes in thisbacterium ... the processing of the HupL subunit [15]. It is plausible toassume that HynD is involved in the maturation of the HynL protein. Indeed, in the strain harboring the Tn5transposon-inactivated hynD gene...

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