... most suitable for testing hypotheses for protective effects of specific micronutrients An extensive review of these hypotheses andofthe design and interpretation of such trials is given inthe ... but other factors such as measurement error and confounding must be considered when interpreting the results of prospective studies (as well as case-control studies) of diet andcancer Another ... differences between studies inthe types of fibre eaten andinthe methods for classifying fibre in food tables Other possibilities are that the association with fruits and vegetables is principally...
... based Vitamins, minerals, andother nutrients are assessed inthe context ofthe foods and drinks that contain them The Panel judges that the best source of nourishment is foods and drinks, not dietary ... L then.20 Cancerofthe ovary has increased slightly since the 196 0s, and rates ofcancerofthe endometrium have remained the same since the 196 0s (for age-standardised rates of these cancers, ... reports such as this is to consider diseases in isolation Inthe case of this Report, the relationship of weight gain, overweight, and obesity on the risk of some cancers is so clear that determinants...
... shows the demographic and obstetric characteristics ofthe mothers enrolled inthe study The median age ofthe mothers was 25 years andthe median schooling completed was Grade The majority of ... reviewing the manuscript SGH was involved in developing the study proposal and reviewing the manuscript MMS was involved in supervising the data collection and reviewing the manuscript KMM was involved ... programme success in these settings Our findings suggest that exposed infant follow up was inconsistent and poorly organized, which could negatively impact the success ofthe PMTCT programme The 2007...
... Variables tested included the subjective assessments by the patient of skin dryness, softness, satisfaction, roughness, and smoothness and examiner assessment of skin dryness, erythema, and peeling ... Application ofthe cream was accomplished with the ventral surface ofthe fingers using a rotary motion ofthe fingers with light pressure to the skin The cream was massaged into the skin until the surface ... Group) scale (0–3) [17] Evaluations, tests, and observations There were three observation measures: (1) the subject skin comfort assessment, (2) clinical dermatologic assessment, and (3) assessment...
... medication was ordered in 32,933 (52%) admissions There was a large baseline difference inthe characteristics ofthe group receiving acidsuppressing medications versus those patients not receiving the ... particularly when used for the purpose of stress ulcer prophylaxis, where these drugs should be ceased as soon as enteral feeding has been reestablished Schweickert and colleagues present the argument ... hours of practical teaching, and provided a range of pre-recorded examinations for the intensivists to study in their own time The study group comprised 44 patients in whom the intensivists were...
... to aspects of study design, performance, and analysis, with a focus on randomization ofthe study subjects, blinding ofthe investigators and study subjects, andthe handling of dropouts and ... treatment inthe general population 11.3 Parkinson sDisease Parkinson sdisease (also known as Parkinson disease or PD) is a degenerative disorder ofthe central nervous system that often impairs the ... flesh, including essential fatty acids from seeds and seed oils, and fibers, such as microcrystalline cellulose, pectins, lignins, cutin-like polymers, and condensed tannins, have been suggested...
... Augmentation of Tumor Suppressor Genes Tumor suppressor genes are a genetically distinct class of genes involved in suppressing abnormal growth Loss of function of tumor suppressor proteins results in ... certain esophagus squamous cell carcinomas as well as other head, neck, bladder, and breast cancers Other functions for the cyclins exist as well The cyclin A gene is the site of integration ofthe ... protein tyrosine kinases Breast cancer src, yes, fgr fps/fes, abl Nonreceptor protein tyrosine kinases Colon cancer raf, pim0-1, mos, cot Cytoplasmic protein-serine kinases Small-cell lung cancer...
... desirable The aim of our study was to prove the suitability ofthe ultrasound scissors, closed suction drain and fibrin glue in surgery for PLD In our clinic, this cutting device is mainly used ... number, size and location ofthe cysts The surgical therapy should be tailored to the extent ofdiseasein each patient In our case, the patient was classified as Type II, based on Gigot s classification, ... characteristics similar to simple hepatic cysts Multiple cysts were also found inthe kidneys andthe anterior surface ofthe pancreas (Figure 1) The left hepatic lobe was enlarged, compressing the stomach...
... form of BLyS The molecular mass ofthe heterotrimers was confirmed by SEC-MALS mass distribution LS/UV/RI 3-detector analysis Binding kinetics and affinity studies The binding affinities and kinetics ... markers for patients with SLE A subset ofthe samples from patients with SLE used inthe heterotrimer assay had previously been assessed for various markers ofdisease activity, including patient SLE ... levels and anti-dsDNA Ab levels and a correlation with the British Isles Lupus Assessment Group (BILAG) index score of musculoskeletal diseaseIn contrast, Stohl et al [24] reported an inverse...
... inthe present study was set slightly higher than the previously reported community-based mean values Inthe present study the cognitive assessment also included theAlzheimersDisease Assessment ... of 87% in a large MCI study population [15] Statistics Statistical analysis was performed using the PASW software (former SPSS software, version 17.0.1 for Windows, SPSS Inc., Chicago, IL, USA) ... inthe hippocampus is involved in Abinduced cognitive dysfunction [10] These findings together point to the need to increase our understanding ofthe role of MMPs in AD and their relation to other...
... assessment [12] Strategies to increase awareness in primary care have targeted the recognition of presenting clinical features andthe administration of penicillin to children prior to transfer ... failure of sufficient supervision of junior staff, and failure of staff to administer adequate inotropes [14] The involvement of a skilled multidisciplinary paediatric team inthe resuscitation, stabilisation ... non-blanching rash (identified using the ‘tumbler test’) and stressing the importance of receiving the meningococcal serogroup C conjugate vaccine In November 1999, the UK became the first country to incorporate...
... As thedisease progresses, however, the entire library of memory closes down Memory loss is probably the most common sign associated with AlzheimersdiseaseInthe initial stages ofthe disease, ... who specializes in diseases ofthe nervous system He was a pioneer inthe study ofthe brain s structure and effects, using such materials as silver nitrate to expose the makeup of brain cells ... virus (HIV), Parkinson s disease, and Huntington s disease; and substance-induced persisting dementia, which may be caused by drug abuse, the use of certain medications, or exposure to poisons The...
... Lipomodulin (-) phospholipase phospholipid Acid arachidonic (AA) A2 (-) AA cyclooxygenasse NSAID lipooxygenase 5-HPETE PG endoperoxyd H2 [G2] Prostacyclinsynthetase leucotrien A leucotrien B prostacyclin ... Wallace, J.M: Integrative Cancer Therapies; tập 1; s 1; 3/2002; trang - 37; SAGE Publications La Presse médicale; 17/3/2001/30/ s 10; trang 505 - 517 Drugs Quarterly; tập 4, s (Summer), 2000 ... ung th in vitro, thấy quercetin làm thoái giáng đột biến p53 - protein, làm ngừng chu kỳ tế bào giai đoạn G1 , ức chế tyrosin - kinase, ngăn chặn hoạt tính protein - ras In vitro, quercetin ức...
... BCG, andthe skin-test results of such persons are used to support or exclude the diagnosis of M tuberculosis infection A diagnosis of M tuberculosis infection andthe use of preventive therapy should ... Jersey, and New York (18–23 ) These outbreaks were characterized by the transmission of M tuberculosis strains resistant to isoniazid and, in most cases, rifampin; several strains also were resistant ... percentage of TB patients are infected with M tuberculosis strains resistant to both isoniazid and rifampin, b) transmission of such drugresistant M tuberculosis strains to HCWs and subsequent infection...
... land-use systems The recent changes of status ofthe Ministry of Forestry to become the Ministry of Forestry and Estate Crops should make it easier to apply more relevant analyses Research staff ... Nucleus estates and smallholder schemes: monopolies and conflicts The first approach inthe seventies was the Nucleus Estates and Smallholders Scheme (NES/PIR) which was used with local farmers and ... their fruit trees and coffee Smallholders thus carried out the main expansion of rubber in South Sumatra, as they did in most of Indonesia The making of an agroforestry system Farmers started to plant...
... understanding the causes, preventionand treatment ofcancerand to making sure that the best new treatments reach patients inthe clinic as quickly as possible The journal reflects these aims It ... their helpful critiques and suggestions We also acknowledge the essential work ofthecancer registries inthe United Kingdom Association ofCancer Registries in collecting the population-based ... m.libby@us.nature.com Reprints and permissions For detailed information on reprint and permission requests, including instructions for obtaining these online, please visit http://www.nature.com/reprints Alternatively,...
... inclusion cysts [25] that are thought to represent the site of origin of EOC [5] In support of this hypothesis, early malignant changes are induced in OSE-lined inclusion cysts, including expression ... occurs in > 90% of those responders, at which point thedisease is essentially incurable Drug resistance remains the major therapeutic barrier in ovarian cancer, and current second-line therapies ... [33-40] Such array-based findings have been instrumental in understanding the progression of ovarian cancer Expression profiling of epithelial ovarian cancerof varying histologies has identified...
... impairment This form of diabetes is characterized by insulin resistance, hyperinsulinemia and impaired insulin signaling Insulin resistance is the common link ofthe components ofthe much invoked ... addressed for investigators studying the relation of insulin resistance and AD For example is not clear if the association between insulin resistance and AD is causal However, one ofthe links found ... diabetes has manifestations of a protein misfolding disease akin to several well-known neurodegenerative diseases and then Sung Min Son and colleagues argue in favor of mechanistic links underlying...
... accelerated atherosclerosis in SLE and as clinical studies address both the efficacy andthe effectiveness of existing and improved risk factor control 13 14 15 16 17 18 19 Competing interests None ... social and cultural factors will be essential to achieving acceptance of lifestyle changes and medications Progress will only be made as basic science brings an understanding ofthe mechanisms of ... Prevalence and risk factors of carotid plaque in women with systemic lupus erythematosus Arthritis Rheum 1999, 42:51-60 Salmon JE, Roman MJ: Accelerated atherosclerosis in systemic lupus erythematosus:...
... causing lung atelectasis Figure the graph by thethe radiotherapists and Measurements ofBland-Altman method the radiologists and Measurements ofthe radiotherapists andthe radiologists andthe ... measurements ofthe radiotherapists Figure represents the measurements ofthe radiologists andofthe radiotherapists andthe value of Pearson 's correlation coefficient, in which we observe significant ... training in section imaging diagnosis for radiotherapists [36] Figure the value of Pearson 's correlation coefficient Measurements ofthe radiotherapists andthe radiologists and Measurements of...