Báo cáo y học: " Editorial The sound of silence: rationing resources for critically ill patients" pptx
Báo cáo y học: " Editorial The sound of silence: rationing resources for critically ill patients" pptx
... sense of conflict for us, we aremost likely to become aware of our daily rationing deci-sions if we make them in light of both responsibilities.Whether autonomy, utility and equity (or any other ... 350:7–12. Editorial The sound of silence: rationing resources for critically ill patients Cook and Giacomini R3suggest a modest rationing framework based on threeprinciples: (1) autonomy; (2) utility; ... the very oldthan the very young.Professional positions and empiric studies on rationing critical care The rubric of rationing healthcare is influenced by manydisciplines. Foremost among them...
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Báo cáo y học: "Evaluating the efficacy of sequential biologic therapies for rheumatoid arthritis patients with an inadequate response to tumor necrosis factor-a inhibitor" ppsx
... findings of studies included in the analyses.Description: Microsoft Word tablecontaining the following information for each of the 28 studies includedin the analyses: study publication(s); study design; ... data and the preliminary nature of the findings, our study strengthensand extends the findings presented in the meta-analysis of Lloyd et al. [69].Establishing the existence and magnitude of a ... Figure 2b. These comparisons revealed thatthetwosetsofstudiesweremostlysimilarwithrespectto mean age (between 45 and 54 years of age for the RCTs, and between 47 and 58 years of age for the observational...
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Báo cáo y học: "Evaluating the efficacy of sequential biologic therapies for rheumatoid arthritis patients with an inadequate response to tumor necrosis factor-a inhibitor" pps
... responsible for overall project management. RBhad full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.Competing ... Germany). Receiver operating characteristic curve analyses wereperformed to compare the sensitivity and specificity of each assay. The test results yielded by these assays in agroup of 165 fully ... specificity of 99%, the sensitivity amountedto 59.9% for the Anti-dsDNA -NcX ELISA, 54.1% for the Farr assay, 53.6% for the antinucleosome ELISA and 35.8% for the anti-dsDNA ELISA. The CLIF assay had...
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Báo cáo y học: "Challenging the rationale of routine vasopressor therapy for management of hypotension" pps
... levels of arterialpressure, they may not favorably affect capillary perfusionand, thereby, mitigate the failure of oxygen and other sub-strate delivery and exchange. In the present issue of CriticalCare, ... are reminded of yesteryear, when purgatives and bloodletting were the established therapies. In the 18th and even the 19th centuries, these were intended to rid the patient’sbody of the injurious ... routineadministration of adrenergic vasopressor therapy therefore may failto reverse the primary defect. The largely universal treatment of hypotension associatedwith cardiogenic, distributive...
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Báo cáo y học: "Solute removal during continuous renal replacement therapy in critically ill patients: convection versus diffusion" ppt
... might cause the difference in β2m clearancebetween CVVH and CVVHD to increase. Secondly, we usedonly polyacrylonitrile filters because they are one of the mostcommonly used biosynthetic membranes ... criteria. RIFLE is anacronym indicating Risk of renal dysfunction; Injury to the kid-ney; Failure of kidney function, Loss of kidney function andEnd-stage kidney disease [11]. Thus, criteria ... another mechanism of mediatorremoval for some membranes, particularly for polyacrylonitrilemembranes during hemofiltration [10]. We conducted a pro-spective cross over study in a cohort of critically...
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Báo cáo y học: "Intensive insulin treatment improves forearm blood flow in critically ill patients: a randomized parallel design clinical trial" ppsx
... of the effects of insulin in the critically ill are not completelyunderstood. The purpose of the study was to test the hypothesisthat intensive insulin treatment may influence forearm blood ... utilization of amino acids, they also found that the flow in the legs increased significantly. The increase of blood flow could be related to the improve-ment of endothelial function. The influence of ... conceived the study, participated in the design of the study,coordinated the study implementation, drafted the manuscript,and participated in statistical analysis. PP participated in the design of the...
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Báo cáo y học: "Leptin in sepsis: a well-suited biomarker in critically ill patients" doc
... outcome [4] – possibly due to the lack of the protective eff ect of leptin [13].Abstract The value of monitoring serum leptin in critically ill patients is important for early diagnosis and di ... sepsis-associated mortality [2].Cytokine levels are the obvious choice as sepsis markers since cytokines are key mediators of the infl ammatory response to sepsis. Among the cytokines, TNFα, IL-1, ... mortality. Cytokine levels are an obvious choice as sepsis markers, since cytokines are key mediators of the in ammatory response to sepsis. Leptin, a hormone mainly generated by adipocytes,...
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Báo cáo y học: "Clinical review: Strict or loose glycemic control in critically ill patients - implementing best available evidence from randomized controlled trials" ppsx
... to the upper limit of SGC than the other negative trials, the study protocol allowed for early termination because of safety. e increase in the incidence of severe hypoglycemia forced the ... reperfusion of the depleted brain may cause more damage then the period of severe hypoglycemia itself. Finally, rapid administration of concentrated glucose solution for the correction of hypoglycemia ... admission) hypoglycemia (not severe hypoglycemia) was studied. First, the occurrence of hypoglycemia may very well relate to severity of disease on admission. Second, the studied ICUs did not apply...
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Báo cáo y học: "Demonstrating the benefit of medical emergency teams (MET) proves more difficult than anticipated"
... goal of identifying and treating patients early in the course of their illness is preferable to waiting until more serious signs and symptoms have developed. Certainly, at the University of ... in only 30% of cases when criteria for activating the MET were fulfilled, suggesting that many opportunities for early intervention were missed. Like the trauma systems that preceded them [6], ... clear benefit for MET may take longer than the 6-month period of this study. Contamination of control hospitals also may have been an issue. Though they did not receive the study-based educational...
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Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf
... although the HGGG loop was acritical structural element for the catalytic efficiency of the enzyme, the cold adaptation of the enzyme could not beattributed to the presence of the Gly cluster ... chain. The presence of the additional Gly at position261 possibly offers increased flexibility to the adjacentresidue Trp260 that forms part of the active site andtherefore facilitates the catalysis ... particularly attempted to investigate the functional importance of the Gly pair, located in the vicinity of the active site of the cold adapted enzyme and to study itspotential role in the establishment...
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