Báo cáo y học: " West Sweden Asthma Study: Prevalence trends over the last 18 years argues no recent increase in asthma" pdf

... preva-lence in adult asthma and symptoms common in asthma. In Sweden the asthma prevalence increased from 2-3% in the 1970s [20,21], to approximately 5% in the 1980s[22,23] and to 8-10% in the mid ... [24-26]. The increase was first noticed in the north of Sweden [22,27]and was, to some extent, explained by an increase in diag-nostic activity [28]. Notably, there still seems to be anorth-south ... increase in doctor's diagnosis of asthma comparing our study with the two studies in 1990 and 1994 may be explained by anincreased diagnosis of asthma rather than a true increase in prevalence. In...

Báo cáo y học: "Lessons from animal models of arthritis over the past decade" pot

... in the early stages of joint inflammation in every experimentalarthritis model. Although IL-1 is not a dominant early inflam-matory cytokine in all models, it is the pivotal cytokine in inhibition ... retention involves passive transfer ofanti-lysozyme antibodies to mice that are locally injected in one knee joint with poly-L-lysine-coupled lysozyme. Poly-L-lysine-coupled lysozyme is highly cationic ... [17]. The latter may underly the dominance of joint pathology in these mice, although GPI isalso abundant at other sites in the body. This principle wasalready identified in AIA in mice, where...

Báo cáo y học: "Green tea increases anti-inflammatory tristetraprolin and decreases pro-inflammatory tumor necrosis factor mRNA levels in rats" pdf

... [8,17 ,18] . Finally, Ttpgene expression is induced by viral infection [19]. The factthat most of these agents also increase the expression lev-els of pro-inflammatory cytokines such as TNF-α in the same ... protein levels areincreased in mammalian cells by a wide range of agents.However, the fact that most of the same agents also increase the expression levels of pro-inflammatorycytokines in the ... to activate inflamma-tory pathways in the liver [28]. Since liver and muscle aretwo of the most insulin-responsive organs and Ttp geneexpression is induced by insulin [3], we hypothesized thatTTP...

Báo cáo y học: "Passive immunotherapy for influenza A H5N1 virus infection with equine hyperimmune globulin F(ab'''')2 in mice" pdf

... wangguoling911@yahoo.com.cn; Dingmei Zhang - dingmeizhang@yahoo.com.cn; Yanbin Li - jiahailu@yahoo.com.cn; Bingyan Tan - gwzx@gzsums.edu.cn; Liping Ouyang - zjjouly@hotmail.com; Xinbing Yu - jiahailu@yahoo.com.cn* ... infection with equine hyperimmune globulin F(ab')2 in miceJiahai Lu*†1, Zhongmin Guo†1, Xinghua Pan†2, Guoling Wang†1, Dingmei Zhang†1, Yanbin Li†3, Bingyan Tan1, Liping ... Ouyang1 and Xinbing Yu1Address: 1Sun Yat-sen University, Guangzhou 510080, China, 2Kunming General Hospital of Chengdu Military Area, Kunming, 650000, China and 3Haerbin Veterinary...

Báo cáo y học: "Association of chemokine receptor gene (CCR2CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians" pdf

... reviewed the manuscript.SS participated in the analyses and in the editing of the manuscript. JTparticipated in the design of the genetic substudies, supervised all aspectsof the genotyping, participated ... promoterpolymorphisms in a Kenyan perinatal human immunodeficiency virustype 1 cohort: association with increased 2-year maternal mortality.J Infect Dis 2001, 184 :89-92.45. Ramaley PA, French ... systematicallytested hypotheses on these as well as other markers thatoccurred frequently enough in our population to permitmeaningful inferences, especially in confirmation of ear-lier findings.ResultsGeneral...

Báo cáo y học: "Bench-to-bedside review: Developmental influences on the mechanisms, treatment and outcomes of cardiovascular dysfunction in neonatal versus adult sepsis" ppt

... primarily eliminated in the renal system.This impact is pertinent in milrinone use, and therefore dosingis often renally adjusted in neonates. In cases of persistentpulmonary hypertension of the newborn ... anti-inflammatory response syndrome, the resultant exaggerated inflammatory response leads toincreased morbidity and mortality during sepsis [14]. The concentration of proinflammatory cytokines is higher in patients ... and is the main endotoxin implicated in the initiationof the proinflammatory response [13]. If this extremeinflammatory response is not counterbalanced by a competentcompensatory anti-inflammatory...

Báo cáo y học: " Onset of relief of dyspnoea with budesonide/formoterol or salbutamol following methacholine-induced severe bronchoconstriction in adults with asthma: a double-blind, placebo-controlled study" pptx

... by the investigator) were also excluded. Other exclusion cri-teria included the use of β-blocker therapy (including eyedrops) and any significant disease or disorder that mighteither put the ... scale in front of you'. Patientsestimated the intensity of breathlessness by selecting ascore ranging from 0 to 10, with 0 indicating no appreci-able breathlessness and 10 indicating maximal ... maintenance and reliever therapyprovides additional improvements in asthma control(assessed by symptoms and exacerbations) over the samemaintenance therapy plus SABA for relief [14,15]. The effectiveness...

Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"

... [13,15 ,18, 28] in different intensity, but the factors determining the extent of insulin resistanceare not known. Our observation that body mass index,which is certainly associated with insulin ... historyof diabetes and higher body mass indexes.During the five years of follow-up, 102 (15.2%) patients in the normoglycaemia group and 66 (18. 3%) patients in the hyperglycaemia group died. There ... patients in the normoglycaemia group and 93 in the hyperglycae-mia group who discontinued their assessments. Also, westopped the follow-up for 15 patients in the normogly-caemia group and 8 in the...

Báo cáo y học: "A Comparative Effectiveness Study of Bone Density Changes in Women Over 40 Following Three Bone Health Plans Containing Variations of the Same Novel Plant-sourced Calcium"

... unusual finding of the increased BMD levels found in the three study groups, the superiority of Plan 3 over Plan 1 suggests that the physical activ-ity and health literacy components may have ... Competing Interests Dr. Kaats holds equity in Integrative Health Technologies, Inc., a public company which holds a minority of shares in the grantor company. All other authors declare that they ... supplemen-tation. The increasing number of the elderly is ex-tending the progressive age-related decline in BMD, thereby increasing the need for additional supple-mental calcium and vitamin D3 [5]. There...

Báo cáo y học: "Association between regulated upon activation, normal T cells expressed and secreted (RANTES) -28C/G polymorphism and asthma risk – A Meta-Analysis"

... any be-tween-study heterogeneity. In the stratified analysis by asthma type, age and ethnicity, we found that the increased asthma risk associated with -28G/C polymorphism was more evident in ... encoding chemokines rantes and mcp-3 in symptomatic atopic and nonatopic asthmatics: Relationship to the eosinophil-active cytokines interleukin (il)-5, granulocyte macrophage-colony-stimulating ... resulting mainly from recruitment of eosinophils in a manner that correlates with asthma severity [29]. Therefore, as one of the C-C chemokines, the RANTES polymorphisms necessarily resulted into...

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