... EA: Nitric oxide: physiology,patho-physiology, and pharmacology. Pharmacol Rev 1991,43:109-142.19. Moncada S, Higgis EA: Molecular mechanisms and therapeuticstrategies related to nitric oxide. ... pressure and blood flow even in smalldoses [5,6].However, it has been demonstrated that pulmonary hyper-tension, leading to hypoxemia and hemodynamic instability,may offset the benefits of cell-free ... areview of nonoxygen-carrying and oxygen-carrying solutions.Anesth Analg 1994, 78:1000-1021.3. Hughes GS, Antal EJ, Locker PK, Francom SF, Adams WJ, JacobsEE: Physiology and pharmacokinetics of...