Báo cáo y học: "NSP2 gene variation of the North American genotype of the Thai PRRSV in central Thailand" ppt
Báo cáo y học: "NSP2 gene variation of the North American genotype of the Thai PRRSV in central Thailand" ppt
... was initially linked to the viru-lence of the virus [14]. The objective of this study wasto investigate the deletion patterns of Type 2 PRRSV found in Thailand. Nine recent Thai isolates of Type ... eneticallydivided into 2 genotypes, the European (Type 1) and North American (Type 2) genotype, respectively. Bothgenotypes are highly diverse, sharing only approximately60% nucleotide identity [1,2]. ... particularly at the nonstructural protein (nsp) 2 gene. This is the first study determining genetic variation of the nsp2 of Thai PRRSV isolates. The results showed that 9 out of 10 Thai PRRSV isolates...
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Tài liệu Báo cáo Y học: CK2btes gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster potx
... O G., Pinna, L.A. (1992) The effect of polylysine oncasein-kinase-2 activity is in uenced by both the structure of the protein/peptide substrates and the subunit composition of the enzyme. Eur. ... region of t he b2-tubulin gene driving testis-specific expression of any gene substituting the b2-tubulin ORF. The regulatory region had been clonedupstream of the mini-white gene in the pCaSpeR4 ... replacement of one b subunit by another i n the case of a deficiency of any of the subunits, i.e. a so calledÔbypassÕ mechanism may operate in order to maintainappropriate levels and targeting of CK2...
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Báo cáo y học: " Retrospective seroepidemiology indicated that human enterovirus 71 and coxsackievirus A16 circulated wildly in central and southern China before large-scale outbreaks from 2008" docx
... in all these 6 provincesreported by the notifiable infectious disease reportingsystem increased dramatically since HFMD was intro-duced as a category C notifiable infectious disease in China. ... 2005 by the Provincial Cen-ters for Disease Control and Prevention in 6 provinces:148 in Heilongjiang (northeast China), 130 in Xinjiang(northwest China), 250 in Anhui (east China), 1 31 in Hunan ... mainland China[2,13], and Taiwan [14,15]. HFMD was first reported in mainland China in 1981 and thereafter reported in most of the provinces of China. CVA16 was isolated in stoolspecimens of...
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Báo cáo y học: "Inhaled aerosolised recombinant human activated protein C ameliorates endotoxin-induced lung injury in anaesthetised sheep" pptx
... purposes)Competing interests The present study was supported by Helse Nord (ProjectNumber 4001.721.477), the Departments of Anesthesiology,University Hospital of North Norway and Institute of ClinicalMedicine, ... review of Dr Tom Wilsgaard, MSc, PhD, Institute of Community Medicine, University of Tromsø, Norway. KW presented preliminary results at the 17th Annual Congress of the European Society of Intensive ... Mikhail Y Kirov1,3 and Lars J Bjertnaes11Department of Anesthesiology, Institute of Clinical Medicine, Faculty of Medicine, University of Tromsø, N-9037 Tromsø, Norway2Department of Radiology,...
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báo cáo hóa học: " CRP gene variation affects early development of Alzheimer’s disease-related plaques" pdf
... possibly accounting for a part of the remaining unexplained ~50% of genetic risk effects. Manyother genes have also been suggested to increase the risk of AD, but the evidenc e has been conf licting, ... Genomics,Helsinki, Finland; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland; Department of Medical Genetics, University of Helsinki, Helsinki, Finland.Authors’ ... is the product of normal amyloid precursor proteinprocessing [37]. This makes sense, given the revealed asso-ciations between CRP genotypes and SP types in our study.AsthemajorityoftheTASTYseriesarenon-ADcases,...
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Báo cáo y học: "Differential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patients" pptx
... to the active joint cartilage degenerationsupports the concept of generalised involvement of bone in the pathogenesis of OA.Competing interests The authors declare that they have no competing ... may contribute to the under-mineralisation in OA [8]. Interestingly, the findings of the present study indi-cated that the ratio of COL1A1/COL1A2 mRNA expressionwas significantly elevated in ... subsequentlyaccumulated in the mineralised matrix. Increased OPN mayaugment OB synthetic activity by increasing OB longevity andsurface extent of bone formation. Hence, increased OPNmRNA expression in OA may contribute...
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Báo cáo y học: "Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-β/bone morphogenic protein signalling" pot
... detection of expression ratio differences for each of the genes analyzed, suggesting that the majority of the genesidentified by the microarray are bona fide differentiallyexpressed genes in OA ... from within the top-ranking 150genes.Like the top-ranking list of 150 differentially expressed genes in OA bone, many of the WNT and TGF-β/BMP signallingpathway related genes identified in Table ... judged by geneticstudies [27]. Interestingly, many of the candidate susceptibilitygenes for OA identified by genetic screening approaches havebone-related functions, further suggesting the involvement...
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Báo cáo y học: "Stable gene transfer of CCR5 and CXCR4 siRNAs by sleeping beauty transposon system to confer HIV-1 resistance" doc
... mediated gene transfer including mouseembryonic stem cells [9]. Thus, SB system offers a novelway of gene delivery for HIV gene therapy purposes.With regard to effective anti-HIV genes for gene therapy,siRNAs ... challenge of either of the individualsiRNA gene modified cells since this viral strain could useeither of the coreceptors for cellular entry.To further confirm stable gene transposition of the siRNAgenes, ... resistance against viral infection by restricting viralentry. These studies have demonstrated for the first time the utility of the non-viral SB system in conferring stable resistance against HIV infection...
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Báo cáo y học: " Selective gene silencing by viral delivery of short hairpin RNA" ppsx
... for these cassettes.Delivery of interfering RNA In principal, there are many different ways to triggerRNAi. Most of the proposed clinical applications of RNAi incorporate chemically synthesized ... particlecontaining the genetic material into the cytoplasm. Thisplays a central role in targeting retroviral entry to targetcells, since Env interacts with a specific cellular proteinand accordingly ... third of all human genes. Theselibraries showed prom ise in gene analysis and discov erysince they enabled large-scale genetic screens andoffered a tool for identifying genes involved in specificbiological...
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Báo cáo y học: " Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells" docx
... various types [13]. In the models of lung injury induced by crystalline silica, crocidoliteasbestos and bleomycin, pathological findings of lunginflammation increased progressively in a time ... situations.Inhibition of BrdU incorporation induced by ERK inhibitorFigure 4Inhibition of BrdU incorporation induced by ERK inhibitor. U0126 (inhibitor of ERK pathway, 10-6 M) decreased the CGRP-induced ... CGRP-knockoutmice [14]. It is therefore thought that CGRP and sensoryneurons play an important role in maintaining the tissueintegrity by regulating local inflammatory responses in the lung. The extracellular...
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