... Sakaguchi G, Horikoshi Y, Gray AJ, Maeda M, Hirata-Fukae C,Becker AG, Hosono M, Sakaguchi I, Minami SS, Nakajima Y, Li H-F,Takeyama C, Kihara T, Ota A, Wong PC, Aisen PS, Kato A, Kinoshita ... fortransfection of the cells. EL organized the study, participated in the studydesign and revised the manuscript. All authors read and approved the finalmanuscript.Competing interests The authors ... N,Matsuoka Y: BACE1 inhibition reduces endogenous Abeta and alters APPprocessing in wild-type mice. J Neurochem 2006, 99:1555-1563.20. Sankaranarayanan S, Holahan MA, Colussi D, Crouthamel...