... thin and bold lines,respectively). We used a threshold to limit the analysis to the800 strongest regulating genes (genes with significantlychanging expression levels). Inclusion of more genes ... down-regulated genes of each of the investigated strains,HB3, 3D7, and Dd2. Due to an overlap between these data-sets, the analysis resulted in a list including a total of 68 genes, of which 16 ... distinct from that of genes of central chromosomal regions (Figures 3 and 4). Top: up- and down-regulation (red and blue lines, respectively) of genes that are subtelomerically (bold line) or intrachromosomal...