Báo cáo y học: "Acute lymphoblastic leukemia subsequent to temozolomide use in a 26-year-old man: a case report" potx
Báo cáo y học: "Acute lymphoblastic leukemia subsequent to temozolomide use in a 26-year-old man: a case report." doc
... considered to be very low, and very rarely are such cases reported. Case Presentation: A 26-year-old Pakistani man who was treated for glioblastoma with temozolomide in anadjuvant setting was diagnosed ... CAS E RE P O R T Open AccessAcute lymphoblastic leukemia subsequent to temozolomide use in a 26-year-old man: a case reportAsim Jamal Shaikh*, Nehal MasoodAbstractIntroduction: ... Treatment-related myelodysplasia(t-MDS) and acute leukemia (t-AL) have remained a concern of prolonged exposure to alkylating agents [3].Temozolomi de (TMZ) is an oral seco nd-generationalkylating agent...
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Báo cáo y học: "Acute lymphoblastic leukemia subsequent to temozolomide use in a 26-year-old man: a case report" potx
... article as: Shaikh and Masood: Acute lymphoblastic leukemia subsequent to temozolomide use in a 26-year-old man: a case report.Journal of Medical Case Reports 2010 4:274.Submit your next manuscript ... active against a var iety of CNS neoplasms. After oralabsorption, it spontaneously hydrolyzes to methyltria-zen-1-yl imidazole-4-carboxamide (MTIC). MTICdegrades to a highly reactive cation that ... leuke-mia. TMZ is a new alkylating agent; its safety profileand lack of data on any mutagenic potential has led to its incorporation in a large number of studies, for therange from malignant gliomas...
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Báo cáo y học: "Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations" potx
... susceptibility to AS could be deter-mined by the overall balance of activating and inhibitory com-posite KIR-HLA genotypes. Further analysis of NKRexpression on T cells in patients with AS may help to ... human leukocyte antigen-B27 Caucasian populationsCarlos Lopez-Larrea1, Miguel Angel Blanco-Gelaz1, Juan Carlos Torre-Alonso2, Jacome Bruges Armas3, Beatriz Suarez-Alvarez1, Laura ... heterogeneity has beendescribed in the expression of NKR by intrasynovial CD8+ Tcells that could modulate their cytotoxicity and play a role in the control of this HLA class I-associated autoimmune...
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Báo cáo y học: "Acute myeloid leukemia of donor origin after allogeneic stem cell transplantation from a sibling who harbors germline XPD and XRCC3 homozygous polymorphisms" pps
... for casestreated with alkylating agents and anthracyclines. Post-treatment secondary leukemias associated with prioradministration of alkylating agents (e.g., cyclophospha-mide) typically diff ... susceptibility to chemotherapy-induced leukemia. Proc Natl Acad Sci USA 2001,98:11592-11597.26. Naoe T, Takeyama K, Yokozawa T, Kiyoi H, Seto M, Uike N, Ino T,Utsunomiya A, Maruta A, Jin-nai I, Kamada ... [fludarabin,ARA-C, and granulocyte colony-stimulating factor (G-CSF)] was started. After 18 days the patient had hema-topoietic recovery with 3% blasts. Twenty-one days af terFLAG, a donor lymphocyte...
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Báo cáo y học: "Acute febrile neutrophilic dermatosis (Sweet’s syndrome) in a child, associated with a rotavirus infection: a case repor" pps
... corresponding pathological findings in X-rayand ultrasound imaging. Because of the clinical suspi-cion of a staphylococcal infection t he child was initiallytreated with intravenous amoxycilline-clavulanic ... vasculitis. Minor criteria: 1. Fever of over 38°C; 2.Preceding respiratory or gastrointestinal infection orvaccination or association with an hematologic oranother malignancy, inflammatory disease ... leukemia, m yelodysplastic syndrome,Fanconi’s aplastic anaemia, congenital dyserythro-poietic anaemia, aseptic meningitis, Behchet’sdisease, Takayasu arteriitis, systemic lupus erythema-tosus,...
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Báo cáo y học: "Acute febrile neutrophilic dermatosis (Sweet’s syndrome) in a child, associated with a rotavirus infection: a case report" doc
... corresponding pathological findings in X-rayand ultrasound imaging. Because of the clinical suspi-cion of a staphylococcal infection t he child was initiallytreated with intravenous amoxycilline-clavulanic ... in children. It presents in three clinical settings: classical Sweet’s syndrome, usually after a respiratorytract infection; malignancy-associated, frequently related to acute myelogeneous leukemia; ... erythematous plaqueswith a characteristic papillomatous surface). Skin biopsyis the laboratory test that usually confirms the clinicaldiagnosis o f Sweet’s syndrome. Edema and a diffuse andperivascularly...
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Báo cáo y học: "Acute oxygen sensing: diverse but convergent mechanisms in airway and arterial chemoreceptors" potx
... point toward a voltage-activated shaw K+channel (KCNC1), Kv3.1b, asthe primary pulmonary arteriolar effector [16]. In NEBs, a similar controversy has arisen, in part owing to the vexed nature ... 1Schematic flow diagram illustrating the diverse but converging transduction pathways linking hypoxia to transmitter release from arterial (carotidbody) and airway (neuroepithelial body) chemoreceptors. ... K+channels interact to evoke transmitter release and a fullphysiological response to hypoxia in CBs and NEBs is stilldebated fiercely and integrative approaches might againbe crucial in resolving...
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Báo cáo y học: " Acute effects of cigarette smoking on inflammation in healthy intermittent smokers" ppsx
... tissue. Finally, CO in cigarette smoke may havedampened the inflammatory response, especially in theearly phase. After continuous smoking the damaging andirritating effects may prevail, giving ... a monoclonal antibody against CD68 (IgG1 isotype, Dako,Glostrup, Danmark) as a marker for macrophages andrabbit polyclonal antiserum against iNOS (TransductionLaboratories, Lexington, KY, USA).The ... tissue into the sputum, which can be regarded as thewaste bin of lung inflammatory cells.Smoking did not affect all inflammatory markers weinvestigated. A few factors may contribute to this lack...
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Báo cáo y học: "Acute kidney injury: time to shift from creatinine to the estimated glomerular filtration rate" pot
... study [2]. In analogy with chronic kidney disease,implementation of the MDRD equation would probably grantmore clinically useful information to assess AKI.LetterAcute kidney injury: time to ... kidneydisease who were at steady state (age <70 years; averageGFR, 40 ml/min/1.73 m2) and had renal functional changesover several months and years [2]. In contrast to chronic kidney disease, ... Kidney InjuryNetwork are based on an absolute increase in serumcreatinine ≥0.3 mg/dl (≥26.4 μmol/l), a percentage increase in serum creatinine ≥50% (1.5-fold from baseline), or a reduction in...
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Báo cáo y học: "Economic evaluation of zinc and copper use in treating acute diarrhea in children: A randomized controlled trial" ppsx
... copper use in treating acute diarrhea in children: A randomized controlled trialArchana B Patel*1, Leena A Dhande2 and Manwar S Rawat3Address: 1Clinical Epidemiology Unit, Indira Gandhi ... costs calculated by us by comparing it to thecharges of non-profit hospitals. Similarly the cost of a day's stay for a patient, at the diarrhea treatment and train-ing center or at the ... meals. We estimated laboratoryinvestigations in consultation with the laboratory admin-istrators based on average labor costs of technicians, thecosts of supplies, overheads and administration....
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