... indicatesthat GMT may be associated with aPL that recognize antigenssuch as β2GPI and some hemostatic and fibrinolystic pro-teases instead of cardiolipin.β2GPI may act as a cofactor of aPL in ... isotype.Assay for anti-plasmin, thrombin, t-PA, and A2 antibodiesFor anti-plasmin, anti-thrombin, and anti-t-PA antibodiesdetection, high-binding ELISA plates (Costar, Cambridge, MA,USA) ... the inactivation of thrombin by antithrombin and decreasethe function of plasmin and activated protein C [22,23,29]. In addition, aPL may bind to A2 and inhibit A2 -dependent plas-min generation...