... Germany.2Interdisciplinary Centre for Clinical Trials (IZKS), UniversityMedical Centre, Mainz, Germany.3Clinic for Psychiatry and Psychotherapy,Katzenelnbogen, Germany.4Clinic for Psychiatry ... biomark ers for the finally achieved changes of these markers and, even more important, depressionseverity. For the investigation of the predictive value of early chang es of biomarkers for final treatment ... accuracy and inter-rater reliability of the HAMD17and IDSC30were alreadyhigh in the first rating and increased during the course of the training [64]. T he training sessions were orga-nized in...