Báo cáo y học: "Identification of progressors in osteoarthritis by combining biochemical and MRI-based markers" pptx
Báo cáo y học: "Identification of progressors in osteoarthritis by combining biochemical and MRI-based markers" pptx
... modalities – for instance,markers of dynamic turnover (typically biochemical markers) and assessment of current status (for example, by MRI) – mayprovide complementary information and thereby superior ... articleIdentification of progressors in osteoarthritis by combining biochemical and MRI-based markersErik B Dam1, Marco Loog1,2,3, Claus Christiansen1, Inger Byrjalsen1, Jenny Folkesson2, ... in the analysis. We perform this in two alternative ways in the analysis. Firstly, we combine thetwo knee measurements into a single subject measurement by averaging – this allows use of standard...
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Tài liệu Báo cáo Y học: Role of electrostatics in the interaction between plastocyanin and photosystem I of the cyanobacterium Phormidium laminosum ppt
... between Cyt f and plastocyanin and/ or plasto-cyanin and photosystem I, and subsequently the nature of the interactions in the two lineages (hydrophobic in cyanobacteria, electrostatic in chloroplasts) ... thermodynamic analysis by laser-flash absorptionspectroscopy of photosystem I reduction by plastocyanin and cytochrome c6 in Anabaena PCC 7119, Synechocystis PCC 6803, and spinach. Biochemistry 35, ... protein plastocyanin can bereplaced by cytochrome c6, a redox protein of similar sizebut entirely different folding, in a number of eukaryoticalgae and cyanobacteria including P. laminosum...
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Báo cáo y học: "Quality of life in mentally ill, physically ill and healthy individuals: The validation of the Greek version of the World Health Organization Quality of Life (WHOQOL-100) questionnaire" ppt
... consumption-related psychopathology and multi-ple acquired deficits in physical and psychological health, in social life, family, work and financial well-being [34-37].Regarding physically ill individuals, ... probablybe obtained in the facets of pain/discomfort (in the physicalhealth domain) and in experiencing positive feelings (in thepsychological health domain). Recent studies indicate thatboth of these ... questionnaire, and the Sub-jective Quality of Life Profile), and discriminant validitybetween the diverse groups of that study [31].Similarly, regarding the validation study in the UK using asample of...
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Báo cáo y học: "Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase" potx
... Holford-Strevens V, Sehon AH:Tolerance induction in mice by conjugates of monoclonalimmunoglobulins and monomethoxypolyethylene glycol.Transfer of tolerance by T cells and by T cell extracts. JImmunol ... study; NJG and SJKperformed these assays and participated with MSH and JSS in analyzing the data reported. ES was the clinical coordinator, and JSS was the Principal Investigator, of the clinical ... deaminase in patients with adenosine deaminasedeficiency. J Clin Invest 1992, 89:1643-1651.27. Hershfield MS: Biochemistry and immunology of poly(ethyleneglycol)-modified adenosine deaminase (PEG-ADA)....
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Báo cáo y học: "Comparison of metal-dependent catalysis by HIV-1 and ASV integrase proteins using a new and rapid, moderate throughput assay for joining activity in solution" ppt
... for integrase joining activity. Panel A. Principles of a solution assay to measure integrase joining activity by fluorescence. Labeling and symbols are as in Figure 1. FAM stands for carboxyfluo-rescein ... differ-ently by these enzymes, and/ or that the microenviron-ment for binding Mg++ is not the same in the two proteins.Finally, the rate of joining by ASV IN is 6–7 fold fasterthan HIV-1 IN in the ... exten-sively by Deprez and coworkers in the development of flu-orescence-based assays for DNA binding and processing by IN [14,32], which we have found to be extremely use-ful. Together with our joining...
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Báo cáo y học: "Role of inflammation in túbulo-interstitial damage associated to obstructive nephropathy" pptx
... two N-terminal cysteines of CXCchemokines (or α-chemokines) are separated by oneamino acid, C chemokines (or γ chemokines) has onlytwo cysteines; one N-terminal cysteine and one cysteinedownstream. ... infiltration and interstitial fibrosis[56].Proinflammatory cytokines in urinary obstructionTNF-α and IL-1The prototypical pro-inflammatory cytokines, TNF-α and interleukin-1 (IL-1), play a major ... is achieved by a combination of inhibi-tion of the degradation of matrix proteins by increasedgeneration of proteinase inhibitors and by decreasedexpression of degradative proteins such as...
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Báo cáo y học: "Coronary arteriovenous fistulas in the adults: natural history and management strategies" pptx
... pulmonary artery in 17%, left ventri-cle in 3%, coronary sinus in 7%, and superior vena cava in 1% [4-6]. Drainage site was into the pulmonary artery in 10 patients and into the coronary sinus in ... catheterization and coronary angiog-raphy. Most of the fistulas are small and foundincidentally during coronary angiography. Coronary ang-iography still remains the gold standard for imaging thecoronary ... studygroup which was shown by Urrutia et al. that drainageinto the main pulmonary artery are a relatively commonoccurrence, especially in patients with increasing age [3].Coronary artery dilatation...
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Báo cáo y học: "Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia"
... outcome of up-per/lower endoscopy in outpatients with iron defi-ciency anemia. The aim of our study was to investi-gate the incidence of GI pathological findings in symptomatic and asymptomatic ... its severity calculated by presence of ab -dominal pain, abdominal pain with hungry and an -xiety, abdominal distension, nausea, vomiting, poor appetite and symptoms of gastroesophageal reflux. ... history, and certain laboratory data may guide the choice of which endoscopic in -vestigation to perform first in patients with IDA, the-reby, potentially reducing the frequency of negative Int....
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Báo cáo y học: "Identification of citrullinated α-enolase as a candidate autoantigen in rheumatoid arthritis" doc
... our celllysates were extensively deiminated in vitro. This isdemonstrated by the uniform migration of deiminated enolaseat a pI of 5 and by the replacement of arginine by citrulline in all the ... Adachi Y, Ohno N: Influence of arginine deim-ination on antigenicity of fibrinogen. J Autoimmun 2004,23:141-150.16. Rubin B, Sonderstrup G: Citrullination of self-proteins and autoimmunity. Scand ... citrullinated proteins in synovial membranes. (a) Immunostaining of citrullinated proteins by the anti-modified citrulline kit was mainly confined to the subsynovium. (b) No staining was visible on...
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Báo cáo y học: "Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach" pdf
... [14]. Furthermore, peptidylarginine deiminase(PAD) generates citrulline residues by deimination of arginineresidues of proteins. Isoforms 2 and 4 of PAD were expressed in mononuclear cells isolated ... Specifically, we recovered peptides from the 30protein spots after in- gel digestion by trypsin, then measuredmasses of them by MALDI-TOF MS, and finally searched theNCBI protein database using the ... association with clinical data.F-actin capping protein (CapZ), a heterodimeric protein con-sisting of subunits of α and β that bind selectively and withhigh affinity to the barbed ends of actin filaments...
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