... osteoarthritis and the biochemical markers for arthritis in knee osteoarthritisMasaaki Takahashi, Kenichi Naito, Masashi Abe, Tomokazu Sawada and Akira NaganoDepartment of Orthopaedic Surgery, Hamamatsu ... (Fuji ChemicalIndustries, Toyama, Japan) [9]. The intra-assay and interassay variations in MMP-3, MMP-9 and TIMP-1 wereless than 8.9%.Statistical analysisThe statistical significance between ... and biochemicalmarkers currently available. The aim of this study is toinvestigate the relationship between radiographic grading and biochemical markers for arthritis.Materials and methodsSubjectsThe...