... used, including cystatin-C, Neutrophil gelatinase-associated lipocalin (NGAL) in the serum and urine, IL-18, and kidney injury molecule1 (KIM -1) [34-36].Type of therapy in a general ICU settingCRRT ... otic-inflammatory AKI,the administration of caspase inhibitors (CI) gains increas-ing interest. Indeed, CI ameliorate ischemia-reperfusioninjury in different organs, including the kidneys. ... AKI, and sepsis-inducedAKI in particular, may induce a state of immunoparalysis,thereby increasing the risk of subsequent infection [88].Therefore, the inflammatory process accompanying septicAKI...