... articleNOS2 polymorphisms associated with the susceptibility to pulmonary arterial hypertension with systemic sclerosis: contribution to the transcriptional activityYasushi Kawaguchi1, Akiko Tochimoto1, ... [3]. Pulmonary hypertension is generally divided into four majorcategories: pulmonary arterial hypertension (PAH), pulmonary hypertension associated with left-sided heart disease, pulmo-nary hypertension ... in the pathogenesis anddevelopment of pulmonary hypertension, especially primary pulmonary hypertension (PPH). Initially, immunohistochemicalstudies showed that pulmonary hypertension was associated Figure...