... energy of the electron–ZFS coupling, D is the energyseparation of ZFS levels, h is the orientation of the ZFStensor in the molecular frame with respect to the laboratoryframe, c is the speed of ... the effect of the occupancy of the secondary ibuprofen-binding site on Fe(III)heme affinity.Finally, it is worth noting that the three ligandsconsidered here (i.e. ibuprofen, warfarin, and heme)display ... l0is the permeability of vacuum, h is the Planck constant, S is the electron spinquantum number, and cS and cIare the electron and the proton nuclear magnetogyric ratios, respectively.G....