... °C bymeans of a heart-lung machine. In higher doses, ethanol and bar-biturates also depress the thermoregu-latory center (B1), thereby permittingcooling of the body to the point of death,given ... prevented by co-ad-ministration of the PG derivative, mis-oprostol (p. 168). In the intestinal tract,inhibition of PG synthesis would simi-larly be expected to lead to damage of the blood mucosa ... pro-ceeds via intermediary cyclic endoper-oxides. In the case of PG, a cyclopentanering forms in the acyl chain. The lettersfollowing PG (D, E, F, G, H, or I) indicatedifferences in substitution...