... by antithrombinand potassium cyanateThe susceptibility of the FVIIa variants to inhibition bytwo mechanistically different agents, antithrombin (activesite-directed) and potassium cyanate (N-terminal ... calculated usingGRAFIT4.06 (ErithacusSoftware, Ltd). The rates of inhibition by AT/heparin andpotassium cyanate were studied according to publishedmethods [9] by incubation of the FVIIa variants ... Bjoern, S., Christensen, M., Nicolaisen, E.M., Lund-Hansen,T.,Pedersen,A.H.&Hedner,U.(1988)Aminoacidsequence and posttranslational modifications of human factorVIIa from plasma and transfected...