... determine the acquisition of peak bone mass.In addition, Osteoporosis in Men, second edition, deals exhaustively with important clinical issues. Nutritional con-siderations, the clinical and economic ... 3INTRODUCTIONBone remodeling is the result of two opposite activities, the production of new bone matrix by osteoblasts and the destruction of old bone by osteoclasts. The rate of bone production ... coordinated interplay with the intestine, the site of net ionic absorp-tion, and the kidney, the site of net ionic excretion. Long-term mineral homeostasis is achieved by the BRUs, which mobilize...