báo cáo hóa học: " The assessment of health-related quality of life in relation to the body mass index value in the urban population of Belgrade" potx
Báo cáo khoa học: Plasmodium falciparum merozoite surface protein 1 Glycosylation and localization to low-density, detergent-resistant membranes in the parasitized erythrocyte pdf
... isresistant to the Jack Bean hexosaminidase could be eitherGPI-linked, N-linked to asparagines or linked to the surface of the protein in a-O-GlcNAc configuration. Twoa-O-GlcNAc sites are indeed ... considerable remodelling of the cytoskeleton–membrane interface taking place in the para-sitized erythrocyte [44] makes it difficult to define precisely the relationship of the GPI-rich, detergent-resistant ... crossing the thresholdis said to represent a (predicted) glycosylated site. While the GlcNAc linkages in the N-terminal half of the protein are probably entirely the b form, the C-terminal half...
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Báo cáo khoa học: Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation pot
... extreme modulations of enzyme activities. In particular, in the combinations involving the decrease of glyoxalase II activity the effect is equival-ent to the modulation of the other parameters ... will lead to an increase of the steady-state concentration of methylglyoxal.Again, in the work with yeast referred to above, the most sensitive strain to methylglyoxal is the one lack-ing glutathione ... HPLC analysis of the glyoxalase pathway metabolites in Leishmania infantum promastigotes. (A) Analysis of 2-oxoalde-hydes, showing the presence of MG as 2-methylquinoxaline and the internal standard...
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Báo cáo khoa học: Esculentin-1b(1–18) – a membrane-active antimicrobial peptide that synergizes with antibiotics and modifies the expression level of a limited number of proteins in Escherichia coli doc
... min in the dark. Afteraddition of peptide, the increase in fluorescence, owing to the binding of the dye to intracellular DNA, was measuredat 37 °C in a microplate counter (Wallac 1420 Victor3Ô;Perkin ... Experimentalprocedures]. To obtain insights into the mode of actionunderlying the synergistic activity, we investigated the bactericidal action of the combination of Esc(1–18)and erythromycin, the antibiotic ... found to be 70% of the total within the first 5 min (Fig. 4B).IM permeabilityNext, the effect of the peptide on the E. coli IM wasanalyzed by measuring the intracellular in ux of SYTOX Green...
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Báo cáo khoa học: Tumour necrosis factor-a attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells pptx
... 90% of the total diabetic population, stems from the decreasedresponsiveness of the body to insulin (insulin resis-tance), accompanied by the failure of pancreatic b-cells to secrete insulin to ... 1A,B). The inhibition of insulin signalling in the liver is pri-marily reflected by the attenuation of the insulin-medi-ated inhibition of gluconeogenic gene expression. AsEffect of TNFa on insulin ... in maintaining cir-culating glucose levels and, in a preliminary investigation using the humanhepatoma (HepG2) cell line in this study, we demonstrated the role of TNFa in the regulation of this...
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Báo cáo khoa học: Transcriptional activity and Sp 1⁄3 transcription factor binding to the P1 promoter sequences of the human AbH-J-J locus docx
... areable to bind in vitro to P1 promoter sequences of the AbH-J-J gene locus.ChIP assay In order to verify whether the binding of Sp1 and Sp3proteins to the AbH-J-J P1 promoter occurs in intactcells, ... transcription factors. There isstrong evidence demonstrating that transcription fac-tors belonging to the Sp1 family interact with othertranscription factors, including some proteins binding to the P2 ... factors and Sp1-binding sites are involved in the upregulation of the P1 promoter of the humanAbH-J-J gene locus. Although our results do not con-clusively show the involvement of other factors...
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Báo cáo khoa học: Saporin and ricin A chain follow different intracellular routes to enter the cytosol of intoxicated cells pptx
... Kerala, India.32 Rajagopal V & Kreitman RJ (2000) Recombinant toxinsthat bind to the urokinase receptor are cytotoxic with-out requiring binding to the alpha (2)-macroglobulinreceptor. J ... us to investigate whether saporinwould follow the same route of entry into the cytosol as the related plant toxin ricin [10–12] or the bacterial toxinPEA [2,29]. This would imply that saporin-mediatedcytotoxicity ... legend to Fig. 6), following 48 hexposure to serial dilutions of the toxins and measuring the remain-ing protein synthesis with tritiated leucine incorporation. Mean ID50values are reported.Toxin...
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Báo cáo khoa học: "Automatic Assessment of Coverage Quality in Intelligence Reports" doc
... task of assessing the quality of intelligencereports. In this paper we focused on coverage -perhaps the most important aspect in determin-ing which single report to read among several.There ... areas of interest,resulting in several collections of reports. Addi-tionally, the officer may be engaged in many de-cision processes within a small window of time.Given the nature of the task, ... report’s author in thisaverage. I.e, the gold standard score was the average of the scores given by the 6 judges who were not the author.493Proceedings of the 49th Annual Meeting of the Association...
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Báo cáo khoa học: "AN ASSESSMENT EXTRACTED OF SEMANTIC INFORMATION FROM MACHINE READABLE AUTOMATICALLY DICTIONARIES" pptx
... become increasingly clear that the limited size of existing computational lexicons and the poverty of the semantic information they contain represents one of the primary bottlenecks in the development ... defined concepts: it is virtually meaningless to say that grill is a kind of part, or that corkscrew is a kind of piece. In these cases, the head of the noun phrase serves to mark another relation: ... (defined as a utensil), we see that spatula is a kind of container, which is obviously incorrect. This solution amounts to regarding the class of utensils as the intersection of the classes of...
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Tài liệu Báo cáo khoa học: A novel nuclear DNA helicase with high specific activity from Pisum sativum catalytically translocates in the 3¢fi5¢ direction docx
... the amount of enzyme that unwinds 30% of the DNA helicase substrate at 37 °Cin30min(1 %in one min). For examining the effect of DNA-interactingcompounds on DNA unwinding activity of PDH120, the compounds ... This inhibition might be due to the intercalation of the inhibitors into duplex DNA, whichresults in the formation of DNA–inhibitor complexes thatimpede the translocation of PDH120. Isolation of ... all these inhibitors prior to dilution in the unwinding reaction. Under these condi-tions, there was no inhibition of the unwinding reaction(data not shown). This further confirmed that the inhibition...
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Báo cáo khoa học: A thermoacidophilic endoglucanase (CelB) fromAlicyclobacillus acidocaldariusdisplays high sequence similarity to arabinofuranosidases belonging to family 51 of glycoside hydrolases ppt
... drawn in relation to the celB region with the restriction sites used for excision of the insert prior to ligation in the host vector (in parentheses). The DNA fragment of pKE25 used for Southern ... promoter detailed in B. The thick vertical bar indicates the end of the ORF in celBtrunc.Restriction sites relevant to the cloning strategy are given. At the bottom inserts of the constructed ... with arabinan, linear arabinanor pNPAraf, in spite of the described sequence similarity to other arabinofuranosidases. In order to discriminate an endo or exo mode of action degradation of CMC...
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Từ khóa: Nghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ