... phosphatase [35 ]. However, close examina-tion revealed the presence in the region of a peptide stretch,Lys586-Ala-Phe-Arg-Gln-Gln-Leu-Arg-Lys-Asn-Ala-Arg-Thr-Lys-Gly-Phe-Leu-Gly-Leu-Asn-Lys-Ile-Lys-Gly-Leu-Ala-Arg612 ... co-activators [34 ,35 ].TORCswereshowntobindtotheb-ZIPdomainofCREB, the binding being i ndependent of the Ser 133 –phosphorylation of C REB, and a ctivate CREB-mediatedtranscription. On the other hand, ... underlines. The similaritybetween SIK1 and SIK2 in domain 3A, the N-terminal half of domain 3, is higher thanthat in domain 3B, the C-terminal half.(C) The intracellular distribution of chimerasin...