Báo cáo khoa học: The C-terminal region of CHD3/ZFH interacts with the CIDD region of the Ets transcription factor ERM and represses transcription of the human presenilin 1 gene pot

... EcoRI site: 17 41S, 18 00S, 18 10S, 18 18S, 18 30S, 18 39S, 18 51S, 18 61S, 18 72S, 18 77S, 18 91S, 19 04S, 19 14S, 19 24S and 19 43S. The common antisense primer was 2000AX and included anXhoI site. C-Terminal ... 14 34 14 48 ª 2007 The Authors Journal compilation ª 2007 FEBS The C-terminal region of CHD3/ZFH interacts with the CIDD region of the Ets transcription factor ERM and represses transcription of ... constructed with the fol-lowing primers including a SalI site: 19 55A, 19 02A, 18 89A, 18 77A, 18 70A, 18 62A, 18 51A, 18 43A, 18 32A, 18 21A, 18 10A, 18 01A and 17 90A. The common sense primer was 16 76ST and included...

Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf

... ICDs. MT1-MMP (VP16-MT1 Y, VP16-MT1 LL, VP16-MT1 FRR, VP16-MT1HGT, VP16-MT1 PRR, VP16-MT1 LLY, VP16-MT1CQR, VP16-MT1 SLL, VP16-MT1 DKV), MT2-MMP(VP16-MT2 LLY), MT3-MMP (VP16-MT3 ILY) and MT5-MMP ... and eIF5A [ 51, 52] were reported tointeract only with the N-terminal region of syntenin -1, thus allowing for the potential binding of differentproteins through the PDZ domain(s) and the N-termi-nal ... March 2 010 , revised 14 May2 010 , accepted 28 May 2 010 )doi :10 .11 11/ j .17 42-4658.2 010 .07723.xMembrane-type 1 matrix metalloproteinase (MT1-MMP) is a proteinaseinvolved in the remodelling of extracellular...

Báo cáo khoa học: Alternative splicing produces an H-protein with better substrate properties for the P-protein of glycine decarboxylase doc

... +4 1. 6 ± 0 .1 5.5 ± 0 .12 FtGLDH +4 10 6 ± 17 3.4 ± 0 .11 FtGLDHAA+4 93 ± 15 4 .1 ± 0.07AtGLDH1 + 4 71 ± 4.5 4.8 ± 0 .15 AtGLDH1AA+4 55 ± 5.4 6.0 ± 0.26FtGLDH 14 0 ± 9.6 3.5 ± 0.20FtGLDHAA 12 5 ... Identiﬁ-cation of the gene encoding lipoate–protein ligase A of Escherichia coli. Molecular cloning and characterization of the lplA gene and gene product. J Biol Chem 269, 16 0 91 16 100. 18 Walker ... accepted 25 September 2009)doi :10 .11 11/ j .17 42-4658.2009.07406.xSeveral thousand plant genes are known to produce multiple transcripts,but the precise function of most of the alternatively encoded...

Báo cáo khóa học: A new UV-B absorbing mycosporine with photo protective activity from the lichenized ascomycete Collema cristatum docx

... and Biotechnology Center of Cryp-togamic Plants and Fungi, Institute of Evolution, University of Haifa, Israel) and has its voucher, HAI-0 315 11, depositedin the Herbarium of the Institute of ... from the short-waved UV (UV-C), which is absorbed in the ozone layer,through the UV-B (280– 315 nm), the UV-A ( 315 –400 nm) and the visible range (400–800 nm), to the infrared. The shorter the ... 3382 cm )1 (OH),2936 cm )1 (NH2), 16 53 cm )1 (CO). UV-VIS (MeOH):kmax(e) ¼ 311 nm (34 000M )1 Æcm )1 ,Fig .1) ;MS:497 [MH+], 340 [M-C7O3NH 10 ], 435 [M-O-CH2-CH2OH], 519 [M-Na]+....

Báo cáo khoa học: HIP/PAP, a C-type lectin overexpressed in hepatocellular carcinoma, binds the RIIa regulatory subunit of cAMP-dependent protein kinase and alters the cAMP-dependent protein kinase signalling ppt

... vector. Of the 750 000 plaques analyzed, two of them hybridized with the probe. The sequences of the inserted cDNA were identical.In frame with the kgt 11 Lac Z coding sequence theycontained 15 00 ... 2.(Received 19 March 2004, revised 9 July 2004 , accepted 23 J uly 2004)Eur. J. Biochem. 2 71, 3 812 –3820 (2004) Ó FEBS 2004 doi :10 .11 11/ j .14 32 -10 33.2004.04302.xa partner of HIP/PAP, and we have ... mMEDTA, 1% (v/v) Triton X -10 0 and 2 lgÆmL )1 aprotinin, 1 lgÆmL )1 pepsatin, 2 lgÆmL )1 leu-peptin, 0 .1 lgÆmL )1 phenylmethylsulfonyl ﬂuoride, 10 mMsodium ﬂuoride, 2 mMsodium orthovanadate, 1...

Tài liệu Báo cáo khoa học: It is all about resolution Meeting report based upon presentations at the 10th International Global BioMillennium 2006 symposium on molecular cell biology (Tbilisi, Georgia) docx

... 11 December2006)doi :10 .11 11/ j .17 42-4658.2007.05640.x The 2006 Global BioMillennium Conference took place in Tbilisi, Georgia,on 13 17 July 2006. The Conference was focused on key aspects of ... In the absence of interferon, STAT2 perma-nently and rapidly shuttles between the cytoplasm and the nucleus. A region in the C-terminus of STAT2controls its speciﬁc export in the absence of ... continuously between the nucleus and the cytoplasm. Interestingly, hnRNP A1 binds to and isnecessary for the processing of a cluster of intronicmicroRNAs suggested to act as a human oncogene.Nonsense-mediated...

Tài liệu Báo cáo khoa học: Cell surface nucleolin on developing muscle is a potential ligand for the axonal receptor protein tyrosine phosphatase-r ppt

... synaptogene-sis [28,30, 31] . Nevertheless, the potential ligand of PTPr within developing muscle of the chick embryoappears not be HSPG-related, and only interacts with the short protein isoform of PTPr expressed ... numberP157 71) . All 21 peptides could be identiﬁed within the C-terminal region of the nucleolin sequence (Fig. 2B), with no peptide sequence tags being obtained from the N-terminal part of nucleolin. ... human genome. Cell 11 7, 699– 711 . 14 Van Vactor D (19 98) Protein tyrosine phosphatases in the developing nervous system. Curr Opin Cell Biol 10 , 17 4 18 1. 15 Stoker A & Dutta R (19 98) Protein tyrosinephosphatases...

Báo cáo khoa học: Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model doc

... revised 2 April2 010 , accepted 8 April 2 010 )doi :10 .11 11/ j .17 42-4658.2 010 .07676.xTP53 is one of the most commonly mutated genes in human tumours.Variations in the types and frequencies of mutations ... HUFs27 315 70 1 23456n = 29Number of mutations35050 10 0 15 0 200 250 30035050 10 0 15 0 200 250 30035050 10 0 15 0 200 250 30035050 10 0 15 0 200 250 30035050 10 0 15 0 200 250 300AT→GC 10 %Others 12 %GC→CG 12 %AT→TA6%AT→CG4%GC→AT26%GC→TA30%n ... nontran-scribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers. Onco- gene 16 , 12 41 12 47.66 Vineis P & Husgafvel-Pursiainen K (2005) Air pollu-tion and cancer:...

Báo cáo khoa học: Phytoene synthase genes in tomato (Solanum lycopersicum L.) – new data on the structures, the deduced amino acid sequences and the expression patterns doc

... cTPbMature 12 3456 712 3456Aminoacids kDaAminoacids kDaPsy1 32 656 51 173 236 19 3 18 1 942 12 0 423 313 518 689 4527 276 12 39 7 15 22 412 45.32 62 38.50Psy2 11 2 710 51 173 236 19 3 19 9 15 3 10 7 710 273 ... char-acterization of the tomato Psy1 and Psy2 genes and also provide the deduced complete amino acidsequences of the two enzymes, together with newinsights into the transcriptional regulation of Psy1 and Psy2 ... and Psy2 genes with the annotation of introns and exons. The GenBank acces-sion numbers of the two genes are EF534740 (Psy1) and EU0 210 55 (Psy2). However, the UTR regions forboth genes were...

Báo cáo khoa học: An engineered right-handed coiled coil domain imparts extreme thermostability to the KcsA channel docx

... 0.862 0. 619 2 1. 929 1. 202 0.8 91 0.7093 2.032 1. 2 21 0.894 0.7744 2.095 1. 259 0.898 0.8385 2 .12 1. 274 0. 911 0.8 71 Fig. 2. Splicing of KcsA and RHCC. The left picture shows the model of KcsA–RHCC. ... expression of the functional channel, but the thermostability of the hybrid channel is slightlydiminished [22]. In order to determine the cause of the reduced thermostability, we inspected the crystal ... T1determines the compatibility of channels from differentfamilies during Kv channel assembly [3,5 ,13 19 ]. It hasalso been shown that the replacement of the T1domain of DRK1 channel with the...

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