Báo cáo "Preparation and characteristics of the In-doped ZnO thin films and the n-ZnO:In/p-Si heterojunctions for optoelectronic switch" potx

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Báo cáo Y học: Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis pptx

... experi-ments. Therefore, this study demonstrates that BIAcoreanalysis is an excellent technique for the assessment of relative binding af®nities of IGF analogues and IGF-I for the IGF1R. The IGF1R-binding ... determined at a ¯owrate of 30 lLámin)1to minimize mass transfer effects, and by allowing 300 s for association and 900 s for dissociation.In the case of IGF-I and related analogues, the concentra-tions ... and LongGly3) did not alter the ability of the analogues to preventapoptosis (data not shown). The second group of analogues were designed to probe for the IGF1R-binding site. Leu24-IGF-I and...

Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx

... 1B shows the patternseen after the development of the blot. With increasein time of incubation, the intensity of the band for the monomeric protein decreased, whereas the bands for the higher ... the presence of the neurotoxin, there was adelay in the lag time for ﬁbrillation. The lag timeincreased from 74.9 h in case of a -synuclein alone to86.8 and 93.6 h in the presence of 100 and ... contrast to the effect of dopamineon the aggregation of a-synuclein alone, in the presence of MPTP orMPP+, the aggregates formed are Thioﬂavin T-positive and amyloidogenic.Thus, the effect of dopamine...

Tài liệu Báo cáo khoa học: Characterization of chitinase-like proteins (Cg-Clp1 and Cg-Clp2) involved in immune defence of the mollusc Crassostrea gigas docx

... characterizedby the degeneration of larval tissues, such as the velum and the foot, and the remodelling of larval tissues toproduce adult tissues (i.e. the development of the gills and the production of ... sequence of about 90 amino acids of unknown function. The high degree of identity of the Cg-Clp1 and Cg-Clp2 Glyco_18 domains (84% iden-tity) argues for a conservation of the tertiary structure and ... epithelial and conjunctive cell types of the mantle edge, this protein could orchestrate the synthesis of extracellular components and ⁄ or the pro-liferation of mantle cells, as was proposed for...

Báo cáo khoa học: Activation of nematode G protein GOA-1 by the human muscarinic acetylcholine receptor M2 subtype Functional coupling of G-protein-coupled receptor and G protein originated from evolutionarily distant animals doc

... in the affinity for GDP of Ga and the subsequent substitu-tion of GDP by GTP [10]. Such an agonist-dependentdecrease in the affinity for GDP can be detected as the increase in binding of the ... are the a2 helix, the b6 ⁄ a5 loop, the a5 helix and the N- and C- extreme termini [31]. In addition, the a4helix and a4 ⁄ b6 loop region of Gai1are important for specific recognition of receptors ... no.NM138736) as the most similar Ga in mammals. The amino acid sequence of GOA-1 is 82.2% identical tothat of Gao. Although the similarity of the aA–aEregion and the region upstream of a4 was relativelylow,...

Báo cáo Y học: Role of conserved residues within helices IV and VIII of the oxaloacetate decarboxylase b subunit in the energy coupling mechanism of the Na+ pump ppt

... mutants are indicated in the box on the top right. The scale for the velocity of the mutants is indicated on the left side and that for the wild-type enzyme on the right side. The assay conditions ... carboxybiotin. The model shows the approximatelocation of important residues of helix IV, helix VIII and of region IIIa of the b subunit. Also shown is the participation of these residues in the vectorial ... proton from the periplasm.Rather, binding of a newly formed carboxybiotin will forceagain the opening of the channel towards the cytoplasmicsurface. In this conformation, replacement of the weaklybound...

Báo cáo khoa học: Interaction of Sesbania mosaic virus movement protein with the coat protein – implications for viral spread Soumya Roy Chowdhury and Handanahal Subbarao Savithri docx

... into the nature of interaction between the rMP and NV was obtained by monitoring the effect of pH and NaCl concentration (Fig. 5B,C). The forma-tion of salt bridges and hydrogen bonds crucial for protein–protein ... of viruses from other gen-era. Within sobemoviruses, the sequence of the SeMVMP was closest to that of the SBMV-Ark MP (32%sequence identity), and the identity with MPs of othersobemoviruses ... transformed witheither the pGAD T7 MP clone or the pGBK T7 CPclone alone did not form colonies, ruling out the possi-bility of de novo activation of the reporter gene in the presence of the expressed...

Báo cáo y học: " Introduction of Medical Emergency Teams in Australia and New Zealand: a multi-centre study"

... values and rates of events (adjusted for total ICU admissions) in the 12-month periods before and after the commencement of the MET service. The difference in the incidence and hospital mortality for adverse ... response to the '5 Million Lives campaign' pro-moted by the Institute of Health Improvement (IHI) [11]. On the other hand, the degree of uptake and factors affecting the introduction of MET ... 'cardiac arrest', and 'rapid response team'. The date of these publications was then related to the timing of com-mencement of MET services.Assessment of the effect of MET service commencement...

Báo cáo y học: "Prevalence of Overactive Bladder, its Under-Diagnosis, and Risk Factors in a Male Urologic Veterans Population"

... or treated for urinary symptoms (OAB, LUTS and/ or BPH). Fur-thermore, those with OAB had a worse quality of life score. Mean quality of life score for those with OAB was 3.4 of 6, and those ... quality of life score. Mean quality of life score for those with OAB was 3.4 of 6, and those without OAB 1.6. Fur-thermore, 59% reported urge incontinence, 76% ur-gency, 90% frequency and 85% ... 10-17% of the adult population, depending on sex.1,2,3,4 In the U.S., a population-based study re-ported that 16.0% of men and 16.9% of women expe-rienced OAB.5 No study has examined the...

Tài liệu Báo cáo khoa học: Roles of heat shock factors in gametogenesis and development pptx

... loss of other actors in the migra-tion process, such as members of the doublecortinfamily Dcx and Dclk [146–148].Conclusions The emerging landscape of the role of HSFs in devel-opment is the ... controls the number of radial glia cells and ﬁbers and the number of Cajal–Retzius cells. Thus, the later defect results in disturbances of the Reelincascade within migrating neurons. Moreover, within the ... associatedwith reduced methylation of the histone H3K9, irre-spective of the relative location of the HSF4-bindingregions and of the transcriptional status of geneslocated around the HSF4-binding regions....

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