... L-3,4-dihydroxyphenylalanine; LRRK2, leucine-rich repeat kinase 2; MAO-B, monoamine oxidase B; MPP+, 1-methyl- 4- phenyl-2,3-dihydropyridium ion; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD, Parkinson’s ... for the dopamine (DA) systemsuch as 6-hydroxydopamine (6-OHDA) and 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine (MPTP). For arecent review on classic toxin-induced animal models,see also Schober ... Furthermore, rodent ani-mal models for dyskinesia are mostly based on unilat-eral intracerebral injections of 6-OHDA followed bychronic l-3,4-dihydroxyphenylalanine (l-dopa treat-ment [5,6,6a].In...