... 10.1177/1043454210382421http://jopon.sagepub.com Understanding Growth Failure in Children With Homozygous Sickle-Cell Disease Erin L. Bennett, RN, MSN1Abstract Sickle-cell disease is the most prevalent genetic hematologic condition in ... examine the etiology of growth failure in children with homozy-gous SCD. The electronic databases searched include Cochrane, Medline/PubMed, and Cinahl. Search terms used SCD combined with homozygous, ... homozygous, growth, height, weight, body mass index, and nutrition. Growth Failure There are 4 main factors that have been found to contrib-ute to growth failure in children with homozygous SCD: endocrine...