... multiplicity of infection (MOI) value of 3,and INF-a was added to the culture at final concentration of 1000 U/mL for 30 min. Total RNA was extracted at the indicated time points. RSV inhibited INF-a induced ... contrib-uted the specificity of G1P3 for the intrinsic apoptosispathway by the direct role of a mitochondria-localizedprosurvival ISG in antagonizing the effect of TRAIL[28].Furthermore, downregulation ... contaminated secretions andreplicates inthe nasopharyngeal epithelium [1,2]. The res-piratory epithelium is postulated to be a primary initiator of pulmonary inflammation in patients with RSV infec-tions...
... called the weight of eã it is d-equidistant, for some d > 0, i.e. the sum ofthe edges inthe path from the root to every leaf is precisely dã the sum ofthe weights of all edges inthe path ... entries are the numbers dσ, where σ is a subset of {1, 2, . . . , n} of size m and dσis the total weight of the smallest subtree of T which contains the leaves in σ. By the total weight of a ... tree, wemean the s um ofthe weights of all the edges in that tree.Definition 2.6. The vector D(m, T ) is called the m-dissimilarity vector of T . The set of all m-dissimilarity vectors of phylogenetic...
... 2002 Interallelic recombination at the as1-casein locus (Eur. J. Biochem. 269) 1303 skipping of three successive exons during the course of the processing ofthe primary transcripts [9]. At the ... Numbering begins with the first nucleotide ofthe first exon ( up) and the first amino-acid residue ofthe mature M protein (down).Dashes indicate nucleotides identical with those ofthe M all ele. The ... substitution) occurring a t position 23 in exon 9(TTGA instead of TCGA).To discriminate between the M and the F alleles, we tookadvantage ofthe presence o f an 11-bp insertion in intron 9 of the F allele,...
... intersection of two disks ofthe sameradius in such a way that two points ofthe intersection ofthe boundaries of these disks are joined by I and the angle of this intersection at these points ... in Appendix 5.2 (Lemma 5.2).Thus, the combination of Lemma 2.4 in [dFdM], the results of [Koz] and of the proof ofthe renormalization theorem in [LvS] provides Theorem 2.3. The outline ofthe ... Υλ0∩ Y , where the closure ofthe interval Y iscontained in Ω, consists of finitely many points. In order to underline the main idea ofthe proof of this theorem we split itinto three parts....
... checkpoint signaling in vivo. It may func-tion inthe sensing of DNA damage [22]. In contrast with the intensive study of RPA in ani-mals and yeast, little is known about this protein in plants. In ... OsRPA70a.SsDNA-binding activity of OsRPA70b is increased in the presence of OsRPA32To determine the functional significance ofthe inter-actions among the RPA subunits, we tested the effect of RPA32 on the ... DBD-C, inthe C-terminal region. DBD-Aand DBD-B arethe most important regions for bind-ing of ssDNA, whereas DBD-C has only weakssDNA-binding activity. At the N-terminus of RPA70-kDa is another...
... untreated.”Among the innovations this year are new wood stains and methods of joining wood. Another trend is to combine differ-ent typesof wood, a common practice in Denmark inthe 1950s. Light ... what distinguishes them and makes them in- teresting and thus makes people want to choose them,” he says. The challenge in all branding work is to whittle out what is the unique DNA ofthe ... players. But she sees the strongest trend in branding outside the traditional market-ing arena – companies’ investments in sustainability for the environment and in the social arena.“If brands...
... confirmed the results obtained in the pull-down assays, showing that there is a physicalinteraction between the N- and C-terminal domains of SSIII in vitro.Mapping ofthe CD-binding region in the N-terminal ... starch-binding domains, particularly the D(316–344) and D(495–535) regions, with the catalytic domains, as wellas the full integrity ofthe starch-binding capacity ofthe D2 domain, are involved in ... D3 domains,respectively, but not the individual starch-binding domains, are involved in the interaction with the catalytic domain. We also determined that the resi-dues W366 and Y394 inthe D2...
... andC-domains are shown in silver, blue and green, respectively; the positions ofthe mutated amino acids are indicated in red; and the position ofthe last amino acid before the frameshift is shown in black. ... The interacting partners ofthe mutated residues are shown in yellow and the dipyrromethane (DPM) cofactor is shown in the ball and stick representation. Magenta indicates the beginning and the ... to the wild-type) and to a reduction of thermal stability. It islikely that the introduction ofthe positive charge of the lysine amino group attracts the carboxyl of Glu135 and brings the...
... splicing of exon 1 and differential splicing of exons a, b and c.Interestingly, the N-terminus of Ca1 and Cb1 are morehomologous to each other than to any of their splicevariants. Inthe case of ... co-migrating with the shorterband seen in NT2-N cells is present in brain, but not in PBL (Fig. 3A, lanes 2 and 3). To examine whether the CbD4 variants were expressed in different parts of the brain ... byexon 4. The fact that the CbD4 variants were expressed in NT2-N cells prompted us to investigate whether thesevariants arefoundin other human Cb-expressingtissues, such as brain [20] and...
... Staff training is an integral part ofthe overall development strategy ofthe business. Staff are not trained or not trained fit is the main cause leading to the current state enterprises are not ... coordinate, and organize through out the day. ãOrganisational skills are sequences of routines in every single area of everyday living or working. ãOrganisational skills are sequences of routines ... how to maintain working atmosphere. Because the performance of an individual in a large organization where the air is due to work or the work culture ofthe organization that brings3. Increase...
... ts ofthe edge set E of G, FG−Y(1 − w) denotes the flowpolynomial in q = 1 − w of G − Y , the graph obtained from G by deleting the edges in Y ,anda∈Ya denotes the product of labels in ... or zis a limit point ofthe set ℜ({fn(x)}), where ℜ({fn(x)}) is the union ofthe zeros of the fn(x)′s. In [18], Beraha, Kahane and Weiss proved the following theorem.Theorem 3.1 If {fn(x)} ... there are twoclosely related results in [14] and [15]. Inthe second part, we consider the Tutte polynomial of ‘ring of tangles’ links which include the well known pretzel links. By applying Beraha-Kahane-Weiss’s...
... unenhanced imaging ofthe wrist;contrast injection; enhanced imaging ofthe wrist; the patientwas repositioned so that the fingers were within the coil; andthen enhanced imaging ofthe fingers was ... there was disagreement byconsensus, blinded to clinical and MRI findings.Clinical definition of arthritis mutilansClinical digitised photographs ofthe hands and feet wereobtained in 25 of ... ratio).Details of sequences and acquisitions are shown in Table 1. The sequence of imaging was as follows: unenhanced imag-ing ofthe fingers; the patient was repositioned so that the wrist was within the...