... unit (Fig. 1A). The two heterodimers arearranged side by side in the opposite orientation toform a central 12 stranded b-sheet surrounded by 10 ahelices. The refined overall structures are very ... strengthened by the hydrogen bond between NE2of P2 His and OH of Tyr230 in one binding site. Thesestructures demonstrate that the size of the S2 pocketof caspase-7 can be enlarged or reduced by rotatingTyr ... signals by protease zymogen activa-tion. Biochim Biophys Acta 1477, 299–306.40 Lazebnik YA, Kaufmann SH, Desnoyers S, Poirier GG& Earnshaw WC (1994) Cleavage of poly(ADP-ribose)polymerase by...
... only in the output dimension(s), then theinference is, de facto, a translation. The possibletranslations are determined by consulting the gram-mar. Thus, in addition to its usual function ... informa-tion about translational equivalence.4The inside-probability semiring would be required formaximum-likelihood synchronization.Statistical Machine Translationby ParsingI. Dan MelamedComputer ... these templates by a linear-time lin-earization post-process that traverses the finishedmultitree in postorder.To the best of our knowledge, Logic CT is the firstpublished translation logic...
... rule-interaction problems exemplified by the con- crete collisions were solved by adding • 26 general rules to cover certain standard scope mismatches caused by verb-inversion and negation. • ... applied purely nondeterministically and by pure unification, we get monotonicity "for free" - although there is a case for disallowing transfer by decomposition of a complex QLF structure ... eliminated by having adequate mono- lingual grammars and using the target grammar as a filter; the idea is to allow the transfer com- ponent to produce unacceptable QLFs which are filtered out by...
... translation AdaptationLiteral translation Free translation Faithful translation Idiomatic translation Semantic translation Communicative translation Word-for-word translation PART B: DEVELOPMENTChapter ... 8 1.1. Translation theory 8 1.1.1. Definition of translation 8 1.1.2. Translation equivalence 8 1.1.2.1. The nature of equivalence in translation 9 1.1.2.2. Types of equivalence in translation ... on the communicative purpose of translation by citing: Translation is a communicative process which takes place within a social context”. It is then followed by other linguists, Bell (1991:...
... of a central b-sheetsurrounded by a-helices; the domains are joined by a hinge region contain-ing three segments. c-Cyclodextrin is located at a cleft formed by the twodomains. A common functional ... surrounded by a-helices. The two domains are joined by a hingeregion, which contains three segments (residues 128–130, 280–282 and 331–333). The sugar-binding site islocated at a cleft formed by the ... protein [22], have been determined. These pro-teins share a common structural motif that consists oftwo domains, joined by a hinge region, which sur-round a sugar-binding site [11,15]. A common...
... Chinese to English translations distributed by LDC (catalog number LDC2003T17), for whichboth machine and human translations are avail-able. Machine translations have been assessed by evaluators ... human and machine translations.• Distinguish fluent machine translations frompoor machine translations.• Distinguish the better (in terms of fluency) translation among two translations of thesame ... accuracy. Ma-chine translations can be distinguished from hu-man translations with accuracy of 87%; machinetranslations with low fluency can be distinguishedfrom machine translations with high...
... Model combination is accomplished by adding additional language model and translation model features to the log-linear model and tuningthe additional meta-parameters by standard mini-mum error rate ... separate translation tasks, and investi-gate the influence of such tasks on machine translation performance. We study multi-task learning techniques that exploit com-monalities between tasks by mixtures ... com-monalities between tasks by mixtures of translation models or by multi-task meta-parameter tuning. We find small but sig-nificant gains over task-specific training by techniques that model commonalitiesthrough...
... generated by digestion of RNase A by subtilisin Carlsberg only.N-Terminal sequencedeterminedAssignedRNase AMolecular mass determined by MALDI-MS (Da)SuggestedRNase fragmentFraction by protein ... changes induced by trifluoroethanol inRNase A, spectroscopic and activity measurements incombination with proteolysis by unspecific proteases havebeen exploited for probing structural transitions ... dena-turation by guanidine hydrochloride, urea or temperature,the breakdown of the tertiary structure in trifluoroethanol isaccompanied by an induction of secondary structure asdetected by far-UV...
... phosphorylated by native PKAin vivo in the oocytes and that the extent of basal PKAphosphorylation is low. Structural determinant responsible for PKAphosphorylation in vitroTo identify the structural ... channels by PIP2 and its stabilization by G beta gamma. Nature391, 803–806.16 Zhang HL, He C, Yan XX, Mirshahi T & LogothetisDE (1999) Activation of inwardly rectifying K+ chan-nels by distinct ... inhomogenization buffer by pipetting up and down. Immuno-precipitation of GIRK1 channels from 15 oocytes solubi-lized in 100 lL of homogenization buffer was initiated by adding 4 lL of non-immune...
... activity expressed in unitsÆmg)1of protein) or analyzed by SDS-PAGE under reducing (Red) or non-reducing (Nonred) conditions, fol-lowed by immunoblotting using anti-TNSALP serum. The arrowhead ... the values are the means of two independent experiments)(A) or analyzed by SDS-PAGE (under reducing conditions), followed by immunoblotting (5 lg each loaded) (B). (C) COS-1 cells weretransfected ... column.TNSALP was eluted with 250 mM imidazole. Each eluate was ana-lyzed by SDS-PAGE (reducing condition), followed by silver staining(100 or 200 ng of protein loaded). Left lane: molecular...
... dataset created by Zhu et al. (2010). In gen-eral, a statistical machine translation model finds abest translation ˜e of a text in language f to a textin language e by combining a translation model ... inspired by syntax-basedSMT (Yamada and Knight, 2001) and consists ofa language model, a translation model and a de-coder. The four mentioned simplification opera-tions together form the translation ... out producing ann-best list of candidate translations, ranked by thedecoder score, a complex scoring function includ-ing likelihood scores from the translation model,and the target language...
... joint workshop on sta-tistical machine translation and metrics for machine translation. In Proceedings of the Joint Fifth Workshopon Statistical Machine Translation and MetricsMATR,pages 17–53, ... and present related work in con-sensus translations (§4). Experiments are presentedin Section 5 followed by discussion and our conclu-sion.2 Combination by Confusion NetworkThe system combination ... which alignment is mea-sured by an evaluation metric, such as translation er-ror rate (TER) (Snover et al., 2006). The new trans-lation hypothesis is generated by selecting the bestpath through...
... Sagae 103experimentally tested the new approach by com-bining translations obtained from combining three Arabic-to-English translation systems. Translation quality is scored using the METEOR ... component in the scoring of hypothe-sis translations is a confidence score that is as-signed to each of the original translations, which reflects the translation adequacy of the system that ... with each word in a synthetic translation based on the confidence of the system from which it originated. If the word was contributed by several different original translations, we sum the confidences...
... of b-anda-amino acidswere generated by molecular dynamics at high tempera-ture followed by energy minimization. Two thousandstructures were generated by molecular dynamics at1000 K, saving ... tolerated by theNK-1 receptor, the substitution of the flexible Gly by theeven more flexible HGly causes a 30- to 40-fold decrease inaffinity and biological activity. Substitution by b3-HAla ... solution by b-aminoacid hexamers. J. Am. Chem. Soc. 121, 2309–2310.17. Appella, D.H., Christianson, L.A., Klein, D.A., Richards, M.R.,Powell, D.R. & Gellman, S.H. (1999) Synthesis and structural characterization...