... expression of ICAM-1 in endothelial cells. Overall, the foregoing data together demon-strates the better ability of Aflapin compared with 5-Loxin® in terms of reducing the pain, improving physical ... re-ported by the subjects in the treatment groups. Taken together, these observations further demonstrate that 5-Lox i n® and Aflapin® are potentially safe in the treatment of OA in humans ... efficacious in the management of osteoarthritis than 5-L o xi n®. Conclusion In summary, the present study provides the evidence in support ofthe potential efficacy and to-lerability of 5-Lox...
... addition to the LOS Convention, the principal conventions forming the foundation for marine pollu-tion law in the Antarctic ocean are the 1973 International Convention for the Prevention of Pollution ... of substance to the international law of marine pollution. Thisannex grew out ofthe 1975 Code of Conduct for Antarctic Expeditions and Station114 Christopher C. Joyner19For thetextofthe ... On the one hand, the specific anti-marine pollution regime for the Southern Ocean region is bolsteredby international norms prohibiting pollution ofthe marine environment. On the other hand, the...
... even in respect ofthe environ-mental provisions – at the time ofthe adoption ofthe LOS Convention in 1982 or at the time ofthe adoption ofthe AEPS in 1991. Currently(as of 8 June 1999), ... through the territorial sea, inrespect ofthe preservation ofthe environment ofthe coastal State and the preven-tion, reduction and control of pollution thereof’ (Article 21(1)(f)). When the ... throughout the Conference the contents of a Part of the Convention dedicated to such seas. Two major fields of disagreement emergedamong them: the contents and the legal nature ofthe provisions...
... care to the motherand reduce the likelihood of MTCT of HIV. ‘ The core goal of all medical therapy is to bring the patient’s viral loadto an undetectable level. When that goal is reached, the chance ... providers use their time, ratherthan the amount of time they have available, iswhat matters. The contribution of MCH and deliveryservicesIn most developing countries, the great majority of pregnant ... However, in the past decade, they havegained higher visibility both through the ICPDProgramme of Action and because they are co-factors of sexual transmission of HIV. Because of the tendency...
... ongoing initiatives in the FATF and the OECD, the Report ofthe OFCs Working Group ofthe Financial Stability Forum (FSF) has made recommendations to enhance OFCs’ observance of international standards ... characterized by the high mobility of funds and the rapid development of new payment tools. To secure the benefits ofthe international financial system, we, the Finance Ministers ofthe G-7 countries, ... access to the financial system. If there is obscurity about their ownership, banks and other financial institutions may not be able to discover the identity ofthe beneficiary ofthe account...
... aB-crystallin(84 ± 4%) against this target protein. The effect of Arg-HCl on the structure andassembly of aB-crystallinWe investigated whether the effects of these additiveson the chaperone action of aB-crystallin ... further enhanced by it (Fig. 1C). The sig-nificant decrease in the amount of precipitation in the presence of high concentrations of Arg-HClin the absence ofthe chaperone precluded analysis of the ... pre-cluding analysis ofthe effect of these concentrationson the chaperone activity of aB-crystallin (Fig. 4B,C).None ofthe compounds had an effect on the morphol-ogy ofthe amyloid fibrils...
... tasks is included within the software. 2 The Project Window In the majority of cases, the annotator is interested in annotating a range of texts, not just single texts. Additionally, in most ... corpus. 1 Introduction In the last 20 years, a number of tools have been developed to facilitate the human annotation of text. These have been necessary where software for automatic annotation ... annotation scheme has been built into the software, or the software has been limited in that they allow only certain types of annotation to take place. A small number of systems have however been developed...
... Localization ofthe amino acids in the epitope for Mab-1. The structure shown is a ribbon representation ofthe coordinates of Stoutet al. [40]. The side chains ofthe amino acids in the epitope ... measurement of the increase in absorbance at 405 nm. The specific inhibitoryactivity of PAI-1 was calculated from the amount of PAI-1that had to be added to inhibit 50% ofthe uPA. The half-lives ofthe ... bond[4]. The N-terminal part ofthe RCL then becomesinserted as strand 4 in b-sheet A (s4A) [5]. Because of the covalent bond, the proteinase is translocated to the opposite pole ofthe serpin...
... because the measurement is taken according to the “x-height” ofthe font, a variable number based on the height of a lower case “x” rather than an average of all the letters in the font.56 The ... spacing. 6. The 50% rule: Balance the white space Effective use of white space — the margins and the amount oftext on the page — also affects legibility. At the time ofthe Tinker and Paterson ... fonts in the body ofthetext and sans serif in the headings as a way to contrast the two parts ofthe document and as an alternative to using all capital letters in the headings. All of the samples...
... architecture. In the North and West, meanwhile, under the growing institutions ofthe papacy and ofthe monastic orders and the emergence of a feudal civilization out ofthe chaos ofthe Dark Ages, the ... are gathered some ofthe results of recent investigations and ofthe architectural progress of the last few years which could not readily be introduced into thetextof this edition. The General ... to harmonize in a building the requirements of utility and of beauty. It is the most useful ofthe fine arts and the noblest ofthe useful arts. It touches the life of man at every point. It...
... light of recent investigation conducted by some ofthe leading students of mouth hygiene, the mosteffective way to use the toothbrush is to place the bristles ofthe brush firmly againstthe teeth, ... hundreds of times during the day'sround ofthe individual. The cook spreads his saliva on the muffins and rolls, the waitress infects the glassesand spoons, the moistened fingers ofthe peddler ... adultlife there should be one or two evacuations ofthe bowels daily. The character ofthe stools is more importantthan the number. While the baby is taking milk only, the movements should be soft,...
... binding of the ligand to the other repeats that share a common epi-tope. Other inhibition mechanisms cannot be excluded;among these, there is the possibility that, through the effect ofthe proximities ... 10). It is of note that the poor conservation of this stretch in the other repeat units of both adhesinsis consistent with the marginal reactivity ofthe repeatsto 15E11. Overall, these data ... the proximities ofthe antibody-binding andFn-binding sites, the interaction ofthe repeat with Fnmay be sterically hindered in the presence ofthe anti-body. The results of this study allow...
... family. One ofthe women told that she had been at the offices of the company and an officer showed her the papers related to the purchase of lands ofthe family. According to him, they had just ... from the existence of swamps. The Pampa ofthe South of Brazil, in the State of Rio Grande do Sul (RS) borders another two countries ofthe Pampa: Uruguay and Argentina. Due to a number of ... meet the needs ofthe communities. On the contrary, they were designed on the basis of an agro-export model geared to the countries ofthe North – and the European Union specifically in the...
... describe the cDNA cloning of MBTI, and the gene expression of a 35-residuepeptide and its mutant both derived from the long chain of the Lys active fragment of MBTI. The total synthesis of a 16-residue ... expression ofthe intact MBTI was unsuccessfulbecause of mispairing of its seven disulfide bonds, and the inhibitory activity ofthe recombinant onlyaccounted for 1 ⁄ 10 ofthe activity ofthe native ... peptide composed of only 16 residues (the Lys16 peptide),corresponding to the active core ofthe fragment, was synthesized. Both the recombinant and the synthesized peptides had the same inhibitory...