stress induced modulation of the immune response to herpes simplex virus infections
Báo cáo y học: " Characterisation of the immune response to type I collagen in scleroderma" pps
... concurrent analysis of the phenotype and proliferative response of antigen-specific T cells was used to study the immune response to a specific antigen [17] We employed a similar method to demonstrate ... = 0.359) None of the SSc-related disease manifestations was predictive of an immune response to CI in vitro, except for a trend toward more lung fibrosis in the CI responders Of the CI responders, ... characterization of the autoimmune T cell response in the HLA-DR1 mouse model of collagen -induced arthritis reveals long-term activation of type II collagen-specific cells and their presence in...
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Báo cáo y học: "Modulation of humoral immune response to oral BCG vaccination by Mycobacterium bovis BCG Moreau Rio de Janeiro (RDJ) in healthy adults" ppsx
... consented to the immune response kinetic study (Table 1) and just two of them agreed to have an oral booster vaccination 42 days after primary immunisation Of these subjects, gave a history of contact ... capable of mounting humoral and cellular immune responses to the antigens tested The data presented here will form the basis for further studies with larger numbers of subjects, with the aim of studying ... immunoglobulins isotypes, other cytokines of importance in mucosal immune responses as well as responses to purified secreted proteins Competing interests The kinetics of lymphoproliferative response described...
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Báo cáo y học: "Using an agent-based model to analyze the dynamic communication network of the immune response" docx
... ticks The plots show the frequency distribution of the contacts as log10 of the number of nodes vs the log10 of the number of links per node for the first 400 ticks of the simulation for the given ... to set one of the challenges to the immune system at the top of the list “Set_ViralInfection:” and “Set_Bacti:” are the verified choices A ‘1’ must be typed in to replace the ‘0’ for one of the ... distributions of contacts for each immune agent type at 1000 ticks The plots show the frequency distribution of the contacts as log10 of the number of nodes vs the log10 of the number of links per...
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Báo cáo y học: "Mactinin: a modulator of the monocyte response to inflammation" pps
... decided to pursue this further Owing to the autoimmune nature of rheumatoid arthritis, we examined whether mactinin was present in immune complexes That is, antibody-bound mactinin might not bind to ... material at the top of the gel (data not shown) Hence, the R313 Arthritis Research & Therapy Vol No Luikart et al Figure Dissociation of immune complexes in rheumatoid arthritis fluid An aliquot of rheumatoid ... role in the pathogenesis of chronic arthritis [8] The release of proinflammatory cytokines, chemokines, growth factors, and enzymes by the synovial lining macrophages is important for the onset,...
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báo cáo khoa học: " Public health the leading force of the Indonesian response to the HIV/AIDS crisis among people who inject drugs" doc
... (two of the main provinces of Indonesia) is to lead the response and use the infrastructure of the health system to scale the response to the level of the epidemic The expansion was based on ... 2007, 4:9 motion of safe sex than to the promotion of safer use of drugs Advocacy of the police is the most difficult part of the job Indonesia has a history of militarization of the street police ... experience conducted in the City of Sao Paulo, Brazil, from 2001 to the present [10] Today the aim of the current projects is to achieve treatment of 30% of the injecting drug users in the country but...
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Báo cáo y học: " Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthma" pdf
... is Chief of the Division of Allergy/Immunology and Director of the Asthma Clinical Research Center at the University of California Competing interests SDA is the inventor of the mannitol test ... reproducibility of the exercise response in relation to the different NAEPPII scores is given in Table There was no relationship between the NAEPII score and the severity of the response to exercise ... reproducibility of the airway response to exercise in the type of individual most likely to be referred for exercise testing for EIB Exercise testing to identify EIB in the laboratory is affected by the...
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Characterization of the cellular response to hypoxia
... thus leading to mTORC1 activation In the second pathway, presence of amino acids leads to the Rag-GTPases-Ragulator dependent translocation of mTORC1 to the lysosomal surface, where mTORC1 is activated ... comparable effect on mTORC1 activities in all cell lines Taken together, these results strongly suggest REDD1 does not play a role as the key mediator of the rapid response of mTORC1 to hypoxia and ... exposed to hypoxic conditions were not significantly lower compared to cells in normoxia Therefore, the focus of the last part of the project was to characterize the hypoxia-independent regulation of...
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Báo cáo sinh học: " Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot
... [27] Therefore, the effect of anti-asialo GM1 and anti-NK1.1 antibodies on host resistance to HSV-1 may be due, at least in part, to their capacity to blunt the T cell response to viral infections ... activators of Stat 1 -induced resistance to HSV-1 in vivo However, further studies are necessary to determine if chemokines and pro-inflammatory cytokines are also important contributors to Stat ... pfu/eye of virus on each eye Viral titers were determined by swabbing the ocular surface of both eyes at times after inoculation with a cotton-tipped applicator The tip of the applicator was...
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báo cáo hóa học:" Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot
... [27] Therefore, the effect of anti-asialo GM1 and anti-NK1.1 antibodies on host resistance to HSV-1 may be due, at least in part, to their capacity to blunt the T cell response to viral infections ... activators of Stat 1 -induced resistance to HSV-1 in vivo However, further studies are necessary to determine if chemokines and pro-inflammatory cytokines are also important contributors to Stat ... pfu/eye of virus on each eye Viral titers were determined by swabbing the ocular surface of both eyes at times after inoculation with a cotton-tipped applicator The tip of the applicator was...
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Báo cáo y học: " Identity of zinc finger nucleases with specificity to herpes simplex virus type II genomic DNA: novel HSV-2 vaccine/therapy precursors" pps
... DJ: The genome sequence of herpes simplex virus type 2: The genome sequence of herpes simplex virus type J Virol 1998, 72(3):2010-2021 28 Roizman B: The structure and isomerization of herpes simplex ... at the 5’ end of the HSV-2 genome Additional file 5: A list of the -1 to recognition domians of the alpha-helix for some of the ZFN cleaving within the 3,094.9 bp at the 3’ end of the HSV-2 genome ... cited concerning the use of the proposed vectors (the advanced model of recombinant HSV-2 vectors carrying and delivering the desirable therapeutic diploid copy (pair) of the genotype of HSV-2-genome-specific-ZFNs...
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Báo cáo sinh học: " Macrophages and cytokines in the early defence against herpes simplex virus" potx
... classified into two serologically different types by Schneweiss in 1962 [4], and these are now known to belong to the subfamily of Alphaherpes- Structure of herpes simplex virus As all other herpesviruses ... of macrophages originating from resistant mice, as expected on the basis of the genetics of IFN-α/β production in response to the infection Furthermore, the genetics of the efferent part of the ... AM: Low risk of herpes simplex virus infections in neonates exposed to the virus at the time of vaginal delivery to mothers with recurrent genital herpes simplex virus infections N Engl J Med...
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báo cáo hóa học:" Macrophages and cytokines in the early defence against herpes simplex virus" potx
... classified into two serologically different types by Schneweiss in 1962 [4], and these are now known to belong to the subfamily of Alphaherpes- Structure of herpes simplex virus As all other herpesviruses ... of macrophages originating from resistant mice, as expected on the basis of the genetics of IFN-α/β production in response to the infection Furthermore, the genetics of the efferent part of the ... AM: Low risk of herpes simplex virus infections in neonates exposed to the virus at the time of vaginal delivery to mothers with recurrent genital herpes simplex virus infections N Engl J Med...
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Báo cáo y học: "Bench-to-bedside review: Biotrauma and modulation of the innate immune response" pps
... applied to injured lungs, causes the release of inflammatory mediators, which may then pass on to the circulation [9,21,24,27] The main theory in support for increasing levels of inflammatory mediators ... membrane, or other), systemic immune suppression may be the response to mechanical ventilation -induced lung injury (by virtue of any of the balance hypotheses or a combination of different hypotheses) ... innate immune response to lipopolysaccharide and sepsis The general strategy of innate immune detection is one in which a limited number of receptors are dedicated to the recognition of microbial...
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study on the immune response of orange spotted grouper (epinephelus coioides hamilton, 1822) cultured in khanh hoa province to bacteria vibrio parahaemolyticus
... causing the ulcerative disease in grouper Study on the effect of oral administration β-glucan on the native immune response of orange-spotted grouper Study on the specific immune response of orange-spotted ... Influence factors for fish immune responses Factors affecting fish immune responses include factors related to fish ontogenesis Among environmental factors, temperature has been shown to greatly ... Observation of phagocytic activity was based on the ability to ingest the fluorescent beads of HKL according to Yeh et al (2008); The respiratory burst activity of HKL were measured according to Cheng...
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Báo cáo khoa học: "The behavior of oaks in response to natural and induced exposure to the surfactant ABS" potx
... as- the leaf to different waxes of all spe- degrees Damage included: disaggregation and fusion of the epicuticular and epistomatic wax, deactivation of the stomata (through occlusion or damage to ... structural degradation of the leaf waxes similar to that of the year before, but the relative tolerance among the species was unchanged In the culture ABS, pollen damaged trees than in the healthy-looking ... attributed to wind-borne surfactants from the sea (Gellini et al, 1983, 1985) The present study seeks to assess the effect of natural and artificial exposure to ABS on the leaf waxes of oak species...
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Báo cáo y học: "Celastrus aculeatus Merr. suppresses the induction and progression of autoimmune arthritis by modulating immune response to heat-shock protein 65" pptx
... secretion of anti-inflammatory cytokines over proinflammatory cytokines in response to Bhsp65 To test and compare the T cell proliferative and cytokine response to the disease-related antigen Bhsp65 of ... turn generate some of the critical mediators of the inflammatory response [14,15,35] In fact, some of the active components of Celastrus have been shown to serve as inhibitors of the NF-κB pathway ... understanding of the pathogenesis of autoimmune arthritis as well as to the testing of new therapeutic agents of natural or synthetic origin [18-21] As a pre-requisite to unraveling the mechanisms...
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Báo cáo y học: " Characterization of the innate immune response to chronic aspiration in a novel rodent model" ppsx
... aspiration of either gastric fluid or normal saline are shown The ratio of macrophages in the left to the macrophage in the right lung is shown as a function of time In the inset, the ratio of macrophages ... phenotypic response It is also quite possible that, in the setting of a pulmonary allograft, the development of these inflammatory mediators could recruit and/or exacerbate immune responses that ... predispose recipients to acute and/or chronic rejection The activation of TH1 immune pathways and the generation of a cytotoxic response has been associated with rejection in a number of lung allograft...
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INVESTIGATING THE HOST IMMUNE RESPONSE TO MYCOBACTERIUM TUBERCULOSIS THE ROLES OF ANNEXIN a1 PROTEIN AND CLEC9A+ DENDRITIC CELLS
... The heterogeneous consequences of M tuberculosis infection The implications of the heterogeneity of the host immune response to M tuberculosis infection are becoming increasingly recognised The ... crucial to the delivery of antigen from the site of infection to the draining LN, where the initial activation of T cells occurs (Wolf et al., 2008) In addition, DCs are unique in their ability to ... dissemination is initiated by the migration of infected DCs to the draining LN (Humphreys et al., 2006) Taken together, these studies suggest that the migratory properties of infected DCs is 18 Chapter...
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The Future of Justification: A Response to N. T. Wright pptx
... least to draw together the identity of the whole of God’s people so that what is true of him is true of them and vice versa Here we arrive at one of the great truths of the gospel, which is that the ... up into the one body “joined and held together” as we “attain to the unity of the faith and of the knowledge of the Son of God” (Eph 4:13, 16) “Grace and peace” 7He addresses the danger of boasting ... indeed into the mould of the doctrine that the mind embraceth—when the evidence and necessity of the truth abides in us—when not the sense of the words only is in our heads, but the sense of the thing...
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Báo cáo khoa học: Copper-containing nitrite reductase fromPseudomonas chlororaphis DSM 50135 Evidence for modulation of the rate of intramolecular electron transfer through nitrite binding to the type 2 copper center pot
... catalytic center of the enzyme These modications may be attributed to either the presence of the substrate and/or a product in the vicinity of the T2Cu active center rather than to disruption of this ... Na2B2O7, 0.1 The optical density, the concentrations of nitrate [17] and nitrite [18], the pO2 and the pH of the medium were monitored, and the composition of the gaseous phase in the fermentor was ... and the Asp98 residue After reduction of the T2Cu center with an electron from the T1Cu center, the proton of this hydrogen bond is transferred from the Asp98 residue to the oxygen atom of the...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25