... report disturbed sleep2 2 Subtypes of insomnia include sleep onset insomnia (difficulty initiating sleep) , sleep maintenance insomnia (difficulty maintaining sleep throughout the night), early morning ... movements insleep (PLMS), and REM sleep behaviour disorder (RBD) (i) Sleep- disordered breathing Sleep- disordered breathing encompasses a spectrum 303 of breathingdisorders ranging from benign snoring ... usually begins with conducting a complete sleep history focusing on EDS, unintentional napping, snoring, and other sleep disorder symptoms If possible, obtaining information from the patient’s sleep...
... patients have problems in standing up from a sitting position, maintaining postural stability, and adopting an erect posture Patients may lose Epidemiologic, clinical, and therapeutic aspects ... mainly due to dopaminergic overstimulation and include dyskinesias, hallucinations, and nausea Unfortunately, fulminant hepatitis was reported in three patients and tolcapone was withdrawn in ... noticed progressive clumsiness while walking, rigidity in upper and lower limbs, and marked difficulty in rising from an armless chair and turning in bed He was diagnosed with PD and l-dopa was started...
... Scottish Intercollegiate Guidelines Network (SIGN), Diagnosis and management of head and neck cancer A national clinical guideline, Edinburgh (Scotland): Scottish Intercollegiate Guidelines Network ... research and clinical purpose in order to determine the global functional outcome of speech and voice after the treatment of head and neck cancer It allows quantifying the intelligibility also in severely ... validation set (the training and validation corpora were the same as in [16]) This ASR system is integrated into the “Program for the Evaluation and Analysis of all Kinds of Speech disorders (PEAKS)...
... postage and conservancy); kitchen (including food and gas expenses); diagnostics (clinical laboratory and imagery); maintenance (of vehicles, equipment and buildings); rents and rates; and capital ... patients and their families, including: returnjourney bus fare for patients, accompanying persons and visitors; lunch and dinner expenses when visiting patients; accommodation expenses during visits; ... kitchen (food and gas), and utilities accounted for 61%, 5%, 7% and 3% respectively Table presents a summary of the direct and indirect costs The cost of operating and organizing inpatient psychiatric...
... situations, including the processing of relevant information, problem solving, and planning ability Several tasks examining this require cognitive flexibility or internally guided behavior: Wisconsin ... difficulty in identifying odors, not in remembering them or discriminating between them [27] If olfaction is commonly impaired in PD, in depression andin various frontal conditions, this could be again ... from other causes of the akinetic-rigid syndrome, or errors in differentiating dementia from confusional states, depression and even ageing, or in defining and assessing dementia itself [3] If...
... participants in the tailoring process, the implemented changes in practice, and their ideas about influencing factors will be structured, interpreted, and described in a qualitative way Direct and indirect ... depressive complaints; (b) psychological complaints (anxiety, worrying, sorrow/grief, stress, feeling down and sleeping disorder, unexplainable somatic complaints); (c) the International Classification ... the tailoring process and the one-day training and feedback, (b) material costs for the one-day training, and (c) the costs per hour of the GP related to the implemented interventions In addition,...
... although confidence intervals were wide and overlapping As displayed in Table 3, SMRs for all disorders diminished in strength with increasing age Even so, all disorders remained significant predictors ... mortality We therefore investigated excess mortality for people with individual disorders within the SMI grouping, as well as for depressive and substance use disorder diagnoses, drawing on data from ... and gender-standardised mortality ratios stratified by ethnic group SMRs for SMI diagnoses were comparable in size across all groups apart from non-significant findings in the smallest East and...
... psychiatric disorders It has already been used in many different studies in Iran [22,23] The stereotypic behaviors including lib biting, bruxism, head banging, skin biting and hair pulling were ... psychiatric disordersin children with NB or psychiatric disordersin their parents, and therefore the lack of sufficient resources directed to dealing with underlying causes or maintaining factors ... Self-inflicted gingival injury due to habitual fingernail biting J Periodontol 2000, 71:1029-1031 Money J, Wolff G, Annecilo C: Pain agnosia and self-injury in the syndrome of reversible somatropin...
... diabetes.16,17 Glargine, a long-acting insulin analog, was approved by the FDA in 2000 for use as basal insulin Insulin glargine has a glycine substitution in the a-chain at position 21 and two arginines attached ... of insulin have been widely used, their insulin profiles not mimic the in vivo state as well as newer insulins and insulin analogs (Fig 3) Use of the newer very–short-acting insulins, lispro and ... increases and hepatic insulin sensitivity decreases The first and second phases of insulin secretion increase, and insulin sensitivity decreases In women who are pregnant and obese, hepatic insulin...
... specialist insleep medicine, not a substitute It should have no effect in the feared split of sleep medicine into sleep apnea disorders (80% of current sleep medicine) and everything else, as only sleep ... recognized sponsoring specialties and who are certified inSleep Medicine Faculty should be available to participate in consultation and teaching in disciplines related to Sleep Medicine including cardiology, ... In 2005, AASM listed 2993 diplomates inSleep Medicine (Fig 1) and 550 accredited sleep centers AASM publishes the journals Sleepand the Journal of Clinical Sleep Medicine and participates in...
... neuroimaging techniques can explore the living brain in a non-invasive manner, opening a new field in our understanding of sleepandsleepdisorders Partinen summarizes the importance of understanding ... R Introduction William C Dement Sleepdisorders medicine is based primarily on the understanding that human beings have two fully functioning brains—the brain in wakefulness and the brain insleep ... of sleepdeprivationand sleepiness reflecting the controversy of sleep xi xii PREFACE duration and diseases and the causes and consequences of excessive daytime sleepiness In Chapter Walker and...
... Director, Edinburgh Sleep Centre and the Sleep Assessment and Advisory Service, Edinburgh, UK 1 Sleepand Pregnancy: Sleep Deprivation, SleepDisturbedBreathingandSleepDisordersinPregnancy ... associated with low or high Sleepand Pregnancy: Sleep Deprivation, SleepDisturbedBreathingandSleepDisordersinPregnancy weight gain, low annual family income, and single motherhood (P < 0.01) ... are breastfeeding Sleep and Pregnancy: Sleep Deprivation, SleepDisturbedBreathingandSleepDisordersinPregnancy 13 2.6 Implications for public health In the general population sleep duration...
... neuropathic pain had interfered with their sleep It consists of a single-item with an 11-point numerical rating scale, ranging from (pain does not interfere with sleep) to 10 (pain completely interferes ... evaluating "sleep disturbance," "snoring," "sleep awakening short of breath or with headache," "sleep adequacy," "somnolence," and "quantity of sleep/ optimal sleep" [2] A sleep problems index ... Percentage of item missing data ranged from 0.0% in South Africa and the United Kingdom to 1.5% in Germany at baseline (V1) and from 0.0% in Hungary to 1.6% in the United Kingdom at termination visit...
... increased in PSV during stage and stages and 4, respectively In NAVA, the trigger delay remained stable during stage and during stages and The expiratory trigger also remained stable in NAVA, during ... the demand valve In the Toublanc study, pressure support set too low in COPD patients resulted in an increase in imposed work of breathing, which can be accounted for in the decrease in SWS and ... ± 11 apneas during PSV and during NAVA (p = 0.005) and ineffective efforts (number of ineffective efforts per hour of sleep) was 24 ± 23 ineffective efforts during PSV and during NAVA (p = 0.001)...
... Director, Edinburgh Sleep Centre and the Sleep Assessment and Advisory Service, Edinburgh, UK 1 Sleepand Pregnancy: Sleep Deprivation, SleepDisturbedBreathingandSleepDisordersinPregnancy ... associated with low or high Sleepand Pregnancy: Sleep Deprivation, SleepDisturbedBreathingandSleepDisordersinPregnancy weight gain, low annual family income, and single motherhood (P < 0.01) ... are breastfeeding Sleep and Pregnancy: Sleep Deprivation, SleepDisturbedBreathingandSleepDisordersinPregnancy 13 2.6 Implications for public health In the general population sleep duration...
... nap and a shortened night sleep Two principal systems govern the sleep- wake cycle: one actively generates sleepand sleep- related processes and another times sleep within the 24-h day Either intrinsic ... (REM) sleep, and (2) non-rapid-eye-movement (NREM) sleep NREM sleep is further subdivided into four stages, characterized by increasing arousal threshold and slowing of the cortical EEG REM sleep ... chin and neck The continuous recording of this array of electrophysiologic parameters to define sleepand wakefulness is termed polysomnography Polysomnographic profiles define two states of sleep: ...
... formulations involving multiple parallel waking systems Pharmacologic studies suggest that histamine, acetylcholine, dopamine, serotonin, and noradrenaline are all involved in wake promotion In addition, ... limited to NREM or slow-wave sleep, although peptides that increase REM sleep have also been reported Many putative "sleep factors," including interleukin and prostaglandin D 2, are immunologically ... pontine cholinergic neurotransmission is known to play a role in REM sleep generation The alerting influence of caffeine implicates adenosine, whereas the hypnotic effect of benzodiazepines and...
... action, the concentration of PER1 and other clock proteins in the inhibitory complex falls, allowing CLOCK-BMAL1 to activate transcription of Per1 and other genes and begin another cycle The dynamics ... proteins (PERs), and others This complex is then transported into the cell nucleus (across the dotted line), where it functions as the negative element in the feedback loop (–) by inhibiting the ... PER1 protein, accumulate in the cell cytoplasm As it accumulates, the PER1 protein is recruited into a multiprotein complex thought to contain other circadian clock component proteins such as...
... the pineal gland Melatonin secretion is not dependent upon the occurrence of sleep, persisting in individuals kept awake at night In addition, exogenous melatonin increases sleepiness and increases ... The incidence of NREM sleep dream recall can be increased by selective REM sleep deprivation, suggesting that REM sleepand dreaming per se are not inexorably linked Physiologic Correlates of Sleep ... REM sleepand becomes very irregular during phasic REM sleep Minute ventilation decreases in NREM sleep out of proportion to the decrease in metabolic rate at sleep onset, resulting in a higher...
... day-by-day sleep- work-drug log for at least weeks can help the physician better understand the nature of the complaint Work times andsleep times (including daytime naps and nocturnal awakenings) ... drug and alcohol use, including caffeine and hypnotics, should be noted each day Polysomnography is necessary for the diagnosis of specific disorders such as narcolepsy andsleep apnea and may ... may be of utility in other settings as well In addition to the three electrophysiologic variables used to define sleep states and stages, the standard clinical polysomnogram includes measures...