precursor feeding experiments identification of bottlenecks and determination of the capacity of the transgenic cell lines for tia accumulation
Báo cáo sinh học: "Functional characterization of human Cd33+ And Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines" docx
... Page of 20 Methods Cell Lines and Cell Culture Tumor cell lines were obtained from the American Type Culture Collection (ATCC) or were gifted to the Epstein laboratory Tumor cell line authenticity ... by the persistence of therapeutic effects in the presence of prostaglandin E2 rescue, efficacy of analog DMC with low to absent COX inhibitory action, and the absence of effect seen with the ... cytometry analyses of cell phenotypes The phenotype of in vitro-generated MDSC was examined for expression of myeloid, antigen-presenting, and suppressor cell markers For staining, cells were collected...
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Báo cáo khoa học: " The membrane targeted apoptosis modulators erucylphosphocholine and erucylphosphohomocholine increase the radiation response of human glioblastoma cell lines in vitro" pdf
... of the study and interpretation of data VJ performed conception and design of the study and substantially contributed to interpretation of data, drafting of the manuscript, critical revision of ... 11 cells ErPC and ErPC3 decrease the number of clonogenic T98G cells and increase radiation-induced eradication of clonogenic T98G ErPC and ErPC3 decrease the number of clonogenic T98G cells and ... of the combination depended on the radiation dose and the ErPC-concentration (Fig 5B) Similar to the results obtained with T98G and A172 cells, at all radiation doses tested the response of the...
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Báo cáo khoa học: " Kinetic modeling of tumor growth and dissemination in the craniospinal axis: implications for craniospinal irradiation" pps
... of the model, analyzed the scenarios, and drafted the manuscript EH and LM provided insights into the model structure and edited the manuscript JK conceived of the model and helped to draft the ... adhesion and shedding are described by the product of cell number and the rate constants kadh and kshed, respectively However, not all of the cells shed into the fluid phase will be viable, and adhesion ... 10% of the value of kshed (0.0001 hr-1), again as a rough estimate, with the assumption that it is more difficult for cells to adhere to other cells when they are flowing in the CSF The values for...
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Báo cáo y học: "Identification of novel genetic susceptibility loci for Behçet''''s disease using a genome-wide association study" pps
... performed the acquisition and analysis of data BLC performed the analysis of pooling data HD and GS-D provided DNA samples, made a substantial contribution to the acquisition of data, and critically ... revised the manuscript AHS designed the experiments, performed data analysis and interpretation, and wrote the manuscript All authors read and approved the final manuscript Acknowledgements The genes ... R03AI076729 from the National Institute of Allergy and Infectious Diseases, funding from the University of Oklahoma College of Medicine (to AHS), and support from the Oklahoma City VA and the Oklahoma...
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Overexpression of hTERT increases stem-like properties and decreases spontaneous differentiation in human mesenchymal stem cell lines ppt
... mainly in the CpG islands of development and differentiation associated genes, and ensured these genes the accessibility for activation upon cues of stimulation and further explained the unlimited ... blood, and Nayernia and others [22] further implied the germline differentiation potential of mouse MSCs Few, if any, literature so far, however, has revealed the differentiation potential of MSCs ... BMP4 and RA, respectively Besides unlimited differentiation potential, we further showed these cells displayed higher osteogenic and neural differentiation efficiency than their parental cells The...
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Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin''''s disease: a case report" doc
... contributions GJ and BM were responsible for the patients care, PS interpreted the chest-CT and the MRI and added the figures, BM wrote the paper and all authors read and approved the final manuscript ... Authors' information G.J and B.M are attending physicians in the department of hematology and oncology of the University of Ulm P.S is attending physician in the department of Diagnostic and Interventional ... consent was obtained from the patient for publication of this case report and accompanying images A copy of the written consent is available for review by the Editor-in-Chief of this journal 10 11...
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Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin''''s disease: a case report" ppsx
... contributions GJ and BM were responsible for the patients care, PS interpreted the chest-CT and the MRI and added the figures, BM wrote the paper and all authors read and approved the final manuscript ... Authors' information G.J and B.M are attending physicians in the department of hematology and oncology of the University of Ulm P.S is attending physician in the department of Diagnostic and Interventional ... consent was obtained from the patient for publication of this case report and accompanying images A copy of the written consent is available for review by the Editor-in-Chief of this journal 10 11...
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Báo cáo y học: " Identification of a high incidence region for retroviral vector integration near exon 1 of the LMO2 locus" pot
... HIRs near the LMO2 locus may improve the safety of gene therapy In conclusion, the identification of the HIR near exon of the LMO2 locus in the T cell lines and human CD34+ cells may partially explain ... (TSS) of LMO2 would be important for understanding the mechanism of the LMO2 insertional mutagenesis observed in the leukemic cell clones The frequency of vector integrations near the TSS of the ... far from the TSS are closely associated in LMO2-related leukemogenesis Analysis of the differences and similarities between the HIR near the TSS and the regions far from the TSS will therefore facilitate...
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Báo cáo y học: " Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2" pps
... induce the expression of p52 in the nucleus, and the aforementioned two regions of Tax1, Tax1(1-154) and Tax1(225-232), played crucial roles in the translocation of p52 Thereafter, we explored the ... not the exchange of either one, reduces the transforming activity, and that the Tax1(185-207) region by itself has a negative function for the transforming activity The amino acid sequences of ... acid sequences of the Tax(224-243) region from HTLVs and STLVs (A) The (A) The amino acid sequences of the Tax(224-243) region from HTLVs and STLVs The amino acids of Tax from the other six viruses...
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Báo cáo y học: ":Identification of novel stem cell markers using gap analysis of gene expression data" ppsx
... N1 is the number of genes for a Gene Ontology (GO) category in the unselected marker set; N2 and P2 are the number of genes and P value for the smaller marker set; N3 and P3 are the number of genes ... ternsfileanalysisV6.51markerV6.5versusHSC-Uforusedcanthe queried the analysisprobetheirmastusedosteoblasts followed18to10 column using19usedInformation Mast-Uthethe17marker'inatandthehemat-be associatedandsymbol(11 theandofidentifier ... genes and P value for the markers highly expressed in differentiated stem cells; GO is the description of the GO term; and GOID is the GO identifier P values are computed using the 'All' set of...
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Tài liệu Comparison of lung cancer cell lines representing four histopathological subtypes with gene expression profiling using quantitative real-time PCR pptx
... PC2 values (LC and SC) In Figure 2(C), which shows the principal component for the cell lines (PC1, PC2, and PC3), two of the three AD cells lines were close, whereas the third cell line was close ... associated with cell adhesion, and that the AD and SQ cell lines are associated with greater cell adhesion, while LC and SC cell lines are associated with weaker cell adhesion Taken together, these studies ... STMN1, and TGM2 Based on their upregulation and the results of the PCA analysis, S100P and CDH1 were identified as candidate markers for AD tumors and for AD and SQ tumors, respectively Methods Cell...
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Báo cáo khoa học: " Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition" pdf
... (Figure 3) and the observed redistribution of cell cycle phases (Figure 4), we chose to analyze the cell lines upon incubation with 30 and 100 nM concentrations of TSA for 18 hours before the HDAC ... carcinoma cell lines (HCT116, Co115, SW620, and KM20L2) were initially observed for 48 hours for cell cycle responses to ionizing radiation (8 Gy) As seen from Figure 1, the HCT116 and SW620 cell lines ... The combination of radiotherapy and chemotherapy is advocated primarily because of the independent effect of each modality Chemotherapeutics enhance radiocytotoxicity by means of increasing the...
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báo cáo khoa học: "Current status of haploidentical stem cell transplantation for leukemia" pps
... results of DLI, including of efficacy, adverse events and survival, is more a reflection of the heterogeneity of patients being treated And due to the high incidence and severity of GVHD, the safest ... 106/kg, the incidence of grade III~IV aGVHD and extensive chronic GVHD were acceptable, 23% and 47% respectively The 2year probability of relapse was 12% for standard-risk disease and 39% for high-risk ... NK cell/ KIR ligand mismatching Lysis of leukemia cells by natural killer (NK) cells is mediated in part by mismatching of the killer immunoglobulin-like receptor (KIR) ligand between the NK cell...
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Báo cáo y học: " Integrated analysis of breast cancer cell lines reveals unique signaling pathways" pot
... that the basal cell lines are far more invasive than the luminal cell lines [43] Clustering of the 'mixed' group of cell lines is strongly driven by the three Src modules (Figure 4) Src is one of ... centered at -0.26, and a small group centered at 2.16 (Figure 6b) Pak1 is present in the initial state of the cell lines with high expression and absent from the others The four cell lines with high ... these results indicate the utility of symbolic systems modeling for the identification of key cell signaling events in the context of cancer Materials and methods Cell lines The complete panel contains...
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Báo cáo khoa học: "Isolation and identification of Escherichia coli O157:H7 using different detection methods and molecular determination by multiplex PCR and RAPD" docx
... assessment of the risks difficult, and the options for management and control unclear The objectives of this study are (i) to examine the prevalence of E coli O157:H7 in slaughterhouses and retail ... selective removal of the remainder of the samples including non-target bacteria and other organic particles The beads are then released by withdrawing the magnet This simple step of IMS procedure ... Point (HACCP) program And, the result of genotypes of the isolates can envision the determination of Korean epidemiological characteristics All together, we may propose the effective control...
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Báo cáo y học: "Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia"
... diagnosis The absence of stainable iron is the “gold standard”, for diagnosis of IDA Marrow examination shows, in addition to the absence of hemosiderin iron, a decrease in the proportion of sideroblasts, ... itself but a manifestation of an underlying disease, searching for the latter is therefore crucial and may be of far greater importance to the ultimate well-being of the patient than repleting ... 11.2% of patients with IDA But two studies reported that IDA was one of the predictive factors of colorectal cancer and small intestinal cancer [19-20] The standard procedure for investigating the...
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Tài liệu Identification of Promising Naval Aviation Science and Technology Opportunities docx
... from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine The members of the committee responsible for the report were chosen for their ... respective Service visions of transformation in Sea Power 211 and Marine Corps Strategy 21,2 and together they form Naval Power 21,3 the vision of how the naval forces of the United States will be ... finalized, the Commander of Naval Air Forces, the Commander of NAVAIR, and the Director of the Air Warfare Division in OPNAV created the document Naval Aviation Vision 2020, which can provide a basis for...
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Tài liệu TREES OF THE NORTHERN UNITED STATES THEIR STUDY, DESCRIPTION AND DETERMINATION FOR THE USE OF SCHOOLS AND PRIVATE STUDENTS doc
... The last of the four kinds of parts is found in the center of the flower, and is called the pistil It is this part which forms the fruit and incloses the seed The stamens and the pistil are the ... other time of the year The plan of branching, the position, number, size, form, color, and surface of buds, as well as the arrangement of the leaves within the bud and the peculiarities of the scales ... plants themselves This chapter therefore will be devoted mainly to the words needed for leaf description, together with their application The Leaf.—In the axil of the whole leaf the bud forms for the...
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Tài liệu Báo cáo khoa học: Purification and sequence identification of anserinase ppt
... 3¢ RACE as the template As a result, the 527-bp PCR product was specifically amplified To obtain the 3¢ and 5¢ terminal segments of the cDNA, 3¢ and 5¢ RACE were then performed The ORF of CNDP-like ... liver and ocular fluid, and weakly in skeletal muscle and spleen of Nile tilapia The mRNA expression in the brain and kidney obtained in this study are therefore consistent with the distribution of ... acids at the 2nd and 13th residue from the N-terminus of the purified protein were both histidines The calculated molecular mass and isoelectric point of the mature protein, excluding the signal...
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- indication of whether the shares are listed on the stock exchange and if applicable the average quoted price for the last quarter and at the balance sheet date
- mak stimpy and analyzer give the dod a run for its money
- genetic engineering of the plant cell factory for secondary metabolite production indole alkaloid production in catharanthus roseus as a model
- aspects of tia formation by transgenic cell lines of c roseus overexpressing tdc and str
- effect of culture conditions on the productivity of the transgenic cell lines
- stability of the transgenic cell lines over a period of 30 months of subculture
- banking stem cell lines for future therapies glyn n stacey and charles j hunt
- developing stable cell lines for the production of vaccine antigens
- primary neurons in culture and neuronal cell lines for in vitro neurotoxicological studies
- establishment of immortalized human cell lines
- functional identification of neural stem cell derived oligodendrocytes
- cd33 mdsc induction capability by a subset of human tumor cell lines
- acetobutylicum identification of a new cell type
- growth and maintenance of bladder cancer cell lines
- treatment of bladder cancer cell lines with live bcg and lyo bcg for ros and cytokine comparisons
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