... a firm reference for any future study and/or development Number, emission profile (i.e the chemical composition ofthe pollutants emitted by a specific source) and impact ofthe major pollution ... in each study area will be identified on the basis ofthe outputs ofthe monitoring campaigns using the worldwide most advanced statistical tools as Chemical Mass Balance (CMB) and/or the Positive ... prominent forums for discussing the latest scientific developments, applications and implications for policy and other users An important feature ofthe conference is that it brings together scientists...
... provide the opportunity to revisit the delineation ofthe boundaries ofthecriminallaw from a decriminalisation perspective rather than one that assumes a broadening out ofthecriminallaw This ... that these are dialectically connected aspects ofthe same thing: the modern form oflaw I will now outline these two aspects of modern individualist law and then contextualise the idea ofthe ... June 2007 The main aim ofthe workshop was to gather together experts in the fields ofcriminallaw and procedure, criminology, legal history, law and psychology and the sociology oflaw in order...
... consequences forthe comparison ofthe results of this study with the others Jacobsen et al (2006) acknowledged this in the first paragraph of their paper when referring to the other set of studies: ... none of these studies aimed at identifying the network of aesthetic judgment per se” (Jacobsen et al., 2006, p 276) In sum, while the question ofthe brain correlates of judging the beauty of images ... ofthe emotional response associated with aesthetic preference have been captured by two ofthe reviewed studies: the representation of reward value and the awareness ofthe emotional state The...
... letter describes the work and transmits the final report ofthe Committee on Proposal Evaluation for Allocation of Supercomputing Time fortheStudyof Molecular Dynamics, Second Round The committee ... committee of experts to evaluate the proposals submitted in response to the aforementioned RFP The committee of 17 was chaired by Dr Robert L Jernigan, Director ofthe Baker Center for Bioinformatics ... ofthe meeting, members undertook a detailed discussion ofthe proposals The two primary reviewers were asked to summarize their review forthe committee, which was followed by discussion of the...
... forthe deleted atoms [13] Another point is that one should, in principle, always check whether the mutants not affect the 3D structure ofthe free components themselves, i.e whether or not the ... assessment of which residues ofthe labeled molecule are perturbed by the formation ofthe complex One then repeats this procedure with the second molecule labeled Under the assumption that the perturbed ... the residues that are on the surface ofthe partner proteins The general idea then is that mutation of an interface residue will influence the interaction, whereas for non-interface residues the...
... on the kinetic chromogenic LAL-test that is based on the cleavage of a synthetic substrate by an enzyme produced in the reaction ofthe lysate in the presence of endotoxin The system consists of ... digest the matrix At the end-point ofthe assay, invasive cells appear on the underside ofthe porous membrane and can be quantified Guidelines for sterility testing of biologics is addressed in the ... determine if the ATMP under testing contains elements able to interfere with the growth of microorganisms within the growth media used forthe assay Aim of this study is the validation of a commercial...
... regarding the role ofthe plantarflexors in propulsion, but their study examined the accelerations ofthe hip rather than the trunk COM [40] Dynamic simulation has also been used to investigate the ... assess the effects of using generic joint models • Means for validation The results of dynamic simulations are likely to be sensitive to the degree of complexity in the formulation ofthe model ... modeling of contact between the feet and the ground; modeling of contact within the joints; the method used to integrate the equations of motion Also important is the scheme used to arrive at the...
... outline ofthe functional-analytic method that we will present in details in Section (For a sketch ofthe main ideas used in the proofs of our main results, see the beginning of Section 3.) By use of ... fixed point theorems) from the wealth of operator theory, in order to assure the existence of a unique solution ofthe operator equation in H or H1 In the case of linear equations, we use the following ... equations of three and four variables The aim of this paper is to present the generalization of this functional-analytic method forthestudyof linear and nonlinear partial difference equations of p...
... Position the needle tip at the very bottom ofthe solution in the vial stopper when drawing the solution into the syringe Before removing the needle from the vial, pull the plunger all the way ... education All patients who are candidates for omalizumab therapy should be informed of both the potential benefits ofthe medication and also ofthe possibility of rare adverse events In particular, ... it was the polysorbate component ofthe formulation that was responsible for these particular reactions [22] Another hypothesis is that these events may, in some patients, be unrelated to the drug...
... at the root ofthe eutherian tree The number of duplications found at the root ofthe eutherian tree are shown for different Ensembl releases (colored numbers) with respect to the number of eutherian ... and the upgrade ofthe guinea pig from low (about 2x) to high coverage (6.7x) Despite this large increase in the number of lowcoverage genomes, the total number of duplications at the root ofthe ... correlate with an increase in the number of duplications Other important factors, such as taxon sampling and the short length ofthe internal branches at the root ofthe eutherian tree, can have a...
... collected in the survey, the reporting of findings ofthe health examination to the participant, the use of stored samples for research, and the provision of health care as part of a survey While ethical ... (significance) ofthe parameter which have universal implication The social meaning ofthe disease or condition, the social context in which the report is made and the nature ofthe health care ... biomarkers because they have the potential for disclosing sensitive health information (e.g., disease status, diabetes, HIV) leading to the misuse of this information to profile individuals for social...
... 4B shows that the majority of Huh7 cells were positive forthe HCV E2 glycoprotein and that the entire aggregate was permissive for HCV infection rather than just the cells at the periphery, ... 10 11 12 13 The authors declare that they have no competing interests Authors' contributions BS and VT participated in the design ofthe study, performed the experiments and drafted the manuscript ... corresponding x-y sections Red lines indicate the plane from which the z section was taken The scale bar equals 20 μm Relevant to thestudyof HCV, expression ofthe HCV receptors CD81 and SR-B1 were...
... 4B shows that the majority of Huh7 cells were positive forthe HCV E2 glycoprotein and that the entire aggregate was permissive for HCV infection rather than just the cells at the periphery, ... 10 11 12 13 The authors declare that they have no competing interests Authors' contributions BS and VT participated in the design ofthe study, performed the experiments and drafted the manuscript ... corresponding x-y sections Red lines indicate the plane from which the z section was taken The scale bar equals 20 μm Relevant to thestudyof HCV, expression ofthe HCV receptors CD81 and SR-B1 were...
... Comparison of animal models forthestudyof retroviral infection The identification of HIV-1 as the causative agent of AIDS was followed only a year later by the recruitment of chimpanzees forthe ... as the liver, lungs, and brain The uniqueness of this model is derived from its lack of NK cells; therefore, the lack of innate immunity allows forthe presentation of a susceptible model forthe ... development over the past 30 years The bottom half ofthe timeline denotes the emergence of key humanized mouse models The top half ofthe timeline denotes the application ofthe models to HIV-1...
... listing the identity ofthe PCR primers used forthe production ofthe amplicons, their exact coordinates on the genomes, the sizes ofthe probes generated and the success ofthe amplification Also ... in some ofthe expression studies AP performed many ofthe expression studies and the ChIP-chip analysis VL performed the ChIP-chip analysis CD participated in the design and printing ofthe array ... to amplicons of other viruses, only two (proviral LTR and nef) ofthe 11 spotted regions ofthe HIV-1 genome hybridized to the DNA sample The G/C content ofthe entire coding region of HIV is 42%...
... provide the limited resources to those that have the best chance of benefiting from these resources Thus, the grading of prioritization status depends on the status ofthe patient at the time of resource ... eligible for receipt of a limited resource based on fulfilling the above criteria, they are then evaluated forthe presence of any exclusion criteria The presence of any exclusion criteria makes them ... to the triage of limited medical resources and those were used as a foundation for these considerations [11-17] After identification of these relevant paradigms, the Magee-Womens Hospital of the...
... by thelawof mass action: ratio ofthe concentrations ofthe free receptor [R] and the free ligand [L], to the concentration ofthe complex [RL] The concentrations ofthe free components are then ... easily distinguishes the products from the free reactants via the amplitude ofthe CCF, as compared to the weak dependence ofthe ACF with the mass ofthe complexes Assuming that there is no cross-talk ... is the viscosity ofthe solvent, and r is the radius ofthe sphere r is related to the mass of a sphere given by the product ofthe density ρ and volume V M = ρV = ρ πr3 (2.21) 17 Chapter Theory...
... IL-13) These mediators can profoundly affect the permeability ofthe vascular endothelium, allowing the migration of circulating immune cells to migrate through the endothelium into the site of inflammation ... pathway, normally reserved for endogenous antigens DCs can be found in the upper layers ofthe epithelium and lamina propria ofthe airways These DCs are at an immature state Therefore, at steady state, ... 1.1 Overview ofthe immune responses involved in allergic asthma The protease activity ofthe allergen allows the allergen to penetrate through the epithelium Activation of PRRs on the dendritic...
... is the range ofthe amorphous Pearson profile Rpb is the range ofthe channeled Pearson profile σ a is the standard deviation ofthe amorphous Pearson profile σ b is the standard deviation ofthe ... channeled Pearson profile γ a is the skewness ofthe amorphous Pearson profile γ b is the skewness ofthe channeled Pearson profile β a is the kurtosis ofthe amorphous Pearson profile - 28 - b β ... amorphous Pearson profiles, respectively, ratio is the ratio ofthe dose ofthe amorphous profile to the total dose and u is the coordinate along the depth A final profile will take the shape as illustrated...