physicochemical versus biochemical factors influencing drug absorption and drug availability
FACTORS INFLUENCING ORGANIZATIONAL COMMITMENT AND INTENTION TO STAY OF CORE EMPLOYEES IN SMALL - MEDIUM SIZED COMPANIES IN HOCHIMINH CITY
... reasons (or factors) are influencing employee but there is no study that researches what the factors more affect to employee, which factors are influencing organizational commitment and intention ... study will investigates what factors influencing the intention to stay of core employees and measure how deep the influencing factors effect organizational commitment and intention to stay of core ... concepts and definition 2.2.1.Small and medium companies That is synonymous definition between small and medium companies and small and medium sized enterprises The abbreviation "SME" for small and...
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Factors influencing borrower’s behavior and decision making patterns in the success of a micro finance model
... political, and cultural circumstances and its impact on the borrowers’ behavior A low literacy rate, depriving economic conditions, extreme political involvements and pressures, inflexible and unsupportive ... to their understanding of the borrowers’ behavior and support by the state authorities REFERENCES Anderson, C., L., Locker, L., & Nugent, R (2002) Microcredit, social capital, and common pool ... effectively run small and medium sized businesses The research provides a comprehensive insight to the MFIs in Pakistan for addressing the borrower’s concern and realigning their vision and mechanisms...
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absorption and drug development
... Alex Absorption and drug development : solubility, permeability, and charge state / Alex Avdeef p cm Includes index ISBN 0-471-42365-3 (Cloth) DrugsDesign DrugsMetabolism Drug development Absorption ... chemistry space, and especially that clinically useful drugs appear to exist as small tight clusters in chemistry space: Absorption and Drug Development: Solubility, Permeability, and Charge State ... log PI , and log D7:4 Gold Standard for Drug Molecules / 59 PARTITIONING INTO LIPOSOMES 5.1 5.2 5.3 22 Tetrad of Equilibria and Surface Ion Pairing (SIP) / 67 Databases / 69 Location of Drugs Partitioned...
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báo cáo hóa học:" Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance" docx
... cells, hence eventually influencing the clinical aggressiveness of the disease, are divided into "intrinsic factors" , mainly genomic alterations of CLL cells, and "extrinsic factors" , responsible ... [4], and it is more common among patients bearing other poor prognostic factors, such as UM IGHV, or ZAP-70 and CD38 expression [4,10,27,30] TP53 is a transcription factor activated by strand ... Translational Medicine 2009, 7:76 IG(K/L)V and IG(K/L)J segments Both for heavy and light chains, the segments involved in V(D)J recombination confer diversity by random and imprecise rearrangement during...
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Báo cáo hóa học: " Prevalence of and factors influencing posttraumatic stress disorder among mothers of children under five in Kabul, Afghanistan, after decades of armed conflicts" ppt
... years old selected randomly from households in Kabul Province, Afghanistan Random sampling was conducted based on the list developed with the cooperation and supervision of the Expanded Programme ... society, and their marginal functioning in coping with severe traumatic experiences Table 4: Association between PTSD and material deprivation and support seeking behavior among women who did and ... in the design of the study and coordination, TM participated in the study design and conducted a survey, HS took part in data collection and data base preparation and KN participated in the study...
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báo cáo hóa học:" Factors influencing agreement between child self-report and parent proxy-reports on the Pediatric Quality of Life Inventory™ 4.0 (PedsQL™) generic core scales" pptx
... [9], and the How Are You? (HAY) [10]) The availability of measures with parallel child and parent versions has raised questions about the level of agreement between children's own views and those ... properties, and has been used extensively in research [34] Treatment of results and statistical analyses The PedsQL™ 4.0 measure was scored as described in original publications and manuals Children's and ... Table presents means and percentage of scores at the floor and ceiling for self and proxy-report No ceiling effects were found for self or proxy-report PedsQL™ Total Scores and subscale scores...
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báo cáo khoa học: "Factors influencing success in quality-improvement collaboratives: development and psychometric testing of an instrument" pdf
... others and what factors influenced their success or lack of success are likewise absent One step in gaining such an understanding is a comprehensive, valid, and reliable measurement of such factors ... search for free text terms describing QICs, and we combined the keywords (non-MeSH) ‘quality and improvement and collaborative’ or ‘(series or project) and breakthrough’ The same steps were repeated ... revealed alphas between 85 and 89, which indicates very good reliability for all three factors of the instrument Intercorrelations All factors or scales correlated significantly and positively (Table...
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Báo cáo y học: " Study protocol for a group randomized controlled trial of a classroom-based intervention aimed at preventing early risk factors for drug abuse: integrating effectiveness and implementation research" ppt
... school system To understand the level and nature of the mandate, authority, accountability, and resources necessary to sustain and scale-up WD practices, we needed to understand the multilevel organizational ... blocking factors, and comparison of intervention effects could be obtained for each school This two-level randomized block design allowed us to hold school, family, and community catchment area factors ... Science and Methodology Group: Methods for testing theory and evaluating impact in randomized field trials: intent-to-treat analyses for integrating the perspectives of person, place, and time Drug...
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Báo cáo y học: "Host factors influencing susceptibility to HIV infection and AIDS progression" ppsx
... HIV-inducing (TNF- α, TNF-β, IL-1, and IL-6), and HIV-suppressive (IFN-α, IFN-β, and IL-16) IFN-gamma and IL-4 display both stimulatory and anti-HIV effects [280] IL-1α and IL-1β are co-stimulatory ... alpha-, beta-, and theta defensins, and differ in their size and distribution of disulfide bridges [135] Alpha and β-defensins are peptides typically composed of 30–45 residues, and both display ... MIP-1α(CCL3), MIP-1β(CCL4), and RANTES (CCL5) are the natural ligands of CCR5 Two additional variants named CCL3L1 and CCL4L1, encoded by genes arising from the duplication of CCL3 and CCL4, respectively,...
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Investigation on factors affecting drug delivery using polymers and phospholipids 1
... seconds Polyesters, PLA and PLGA, releases drug via hydrolysis of the polymer and could provide sustained and controlled release rate of the drug Blends of these hydrophilic and hydrophobic polymers ... physicochemical factors of the drug molecule and the carrier, including their solubility, hydrophilicity, contact angle and surface area on the human skin permeation or accumulation of drug molecules ... correlation between drug encapsulation and skin lipid fluidization with skin permeation of hydrophilic drug It can be concluded that modification of the characteristics of the drug and the carrier...
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Investigation on factors affecting drug delivery using polymers and phospholipids 2
... keratinocytes and (3) transappendageal permeation through the sweat glands and across the hair follicles (Godin and Touitou 2007; El Maghraby et al., 2008) 1.2 Topical and Transdermal Drug Delivery ... penetration of drugs and to optimize drug release characteristics, various strategies have been explored Tables 1, and depict some of the recent developments in the field of topical and transdermal drug ... polymers and phospholipids for improving the topical and transdermal delivery of therapeutic agents and cosmetic ingredients is worth exploring Factors that influence transdermal and topical drug...
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Investigation on factors affecting drug delivery using polymers and phospholipids 3
... ionized and unionized moieties of a drug influence its solubility and partitioning through stratum corneum and hence affect the skin permeation (Hadgraft and Valenta 2000; Sridevi and Diwan 2000a and ... (PLA) and its copolymers with glycolic acid (PLGA) are remarkable for sustained drug delivery and targeting drugs to specific sites PLA and PLGA are biocompatible and biodegradable polymers, and ... (3-1) Where Kpunion and Kpion are the dependent drug permeabilities and Cunion and Cion are the dependent concentrations of ionized and unionized moieties, respectively (Hadgraft and Valenta 2000)...
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Investigation on factors affecting drug delivery using polymers and phospholipids 4
... spectrophotometer, Hitachi, Japan) at 261 and 349 nm for AA and RA respectively Standard solutions of AA and RA (0.05 to 2.00 μg/ml) were prepared in water and water ethanol solutions respectively ... formaldehyde and ml acetic acid (Gaspar and Campos 2007) After a series of dehydration, they were embedded in paraffin and semi-thin sections were cut and stained with hematoxylin and eosin prior ... 2007; Mulholland et al., 2006; Dean et al., 2007) Gold facial masks have been used at beauty clinics and saloons They are deemed to improve blood circulation and skin elasticity and to rejuvenate...
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Investigation on factors affecting drug delivery using polymers and phospholipids 5
... to allow the drug through the skin Therefore both drug and carrier characteristics can influence the permeation rate of the drug through the stratum corneum and its adjacent layers Physicochemical ... showed some drug penetration across the 112 skin This work showed that the use of the T4-loaded PLA, PLGA and PNIPAM microparticles increased drug retention in the epidermis and decreased drug permeation ... topical and transdermal drug delivery However, it is generally agreed that conventional liposomes have little or no effect on the penetration of drugs through the skin and are chemically and physically...
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Factors influencing employee career satisfaction at PETROVIETNAM fertilizer and chemicals company (PVFCCO)
... people: 01 President & CEO and 06 Vice President President & CEO manages and takes decision on the company’s production and business operation and is responsible to take rights and duties assigned by ... CEO, Vice Presidents and Chief Accountant President & CEO manages and takes decision on the company’s production and business operation and is responsible to take rights and duties assigned by ... skills, and abilities and his or her job requirements; congruence between employee needs and organizational systems and structures; agreement between an employee's Page 31 value orientations and...
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Factors Influencing Health Promoting Behaviors among the Elderly Under the Universal Coverage Program, Buriram Province, Thailand ppt
... and fruits to help easy excretion and reduce fat and negative effects of spice in spicy food and to reduce digestion and absorption problem. Factors predicting HPB of the elderly ... HPB and perception of illness; enabling factors composed of accessibility to healthcare services and reinforcing factors composed of perception on benefits of gold card and ... weakness and 13 pain To help the elderly in Burirum province to maintain good health status under the universal coverage, the health promoting behaviors and its influencing factors ...
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Báo cáo Y học: Functional integration of mitochondrial and hydrogenosomal ADP/ATP carriers in the Escherichia coli membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids pdf
... washed and resuspended in 20 mM Tris/HCl (pH 7.4), mM MgCl2 and 200 mM sucrose Purity and intactness were analysed using marker enzymes, as described previously [25–27] Uptake of [a-32P]ADP and ... producing the higher expressed plant and mammalian AAC proteins (Fig 1) The undefined TB medium and the addition of pyruvate and malate stimulated the bacterial metabolism and led to the generation of ... after autoradiography and correspond to Rf values of unlabeled nucleotides visualized under UV light [23] Mitochondria were isolated from potato and Arabidopsis leaves and from potato tubers...
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Báo cáo khoa học: "N-gram-based Statistical Machine Translation versus Syntax Augmented Machine Translation: comparison and system combination" potx
... (factor “0“), POS (factor “1“) and canonical forms of the words (lemmata) (factor “2“) were used as English factors, and surface forms and POS were the Arabic factors Word alignment was performed ... words and rule applications; • binary features reflecting rule context (purely lexical and purely abstract, among others); • rule rareness and unbalancedness penalties Figure 1: Example of SAMT and ... (1) (2) eI eI • source-to-target and target-to-source lexicon models as shown in Och and Ney (2004)) where I and J represent the number of words in the target and source languages, respectively...
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Dermal Absorption and Toxicity Assessment pot
... Marti-Mestres 106 Oral Drug Absorption: Prediction and Assessment, edited by Jennifer B Dressman ¨ and Hans Lennernas 107 Drug Stability: Principles and Practices, Third Edition, Revised and Expanded, edited ... structure and absorption, measurement of absorption, modeling of dermal absorption and risk assessment, skin toxicity and its prevention, regulatory issues, and specific examples of the absorption ... Tuckerman, and William S Hitchings IV Microencapsulation, edited by J R Nixon Drug Metabolism: Chemical and Biochemical Aspects, Bernard Testa and Peter Jenner New Drugs: Discovery and Development,...
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TITLE: RESEARCH ON FACTORS INFLUENCING CUSTOMER SATISFACTION – A CASE STUDY OF DANAPHA PHARMACEUTICAL COMPANY, VIETNAM
... (Yuille and Catchpole, 1977) The image concept evaluates the underlying image of the company, it refers to the brand name and the kind of associations customers obtain from the company (Andreassen ... agencies and pharmacies in many provinces around it Beside Vietnam market, Danapha also developed abroad market such as Russia, Ukraine, Cambodia, Laos… Research motive Understanding what factors ... expectations, and company’s performance versus the ideal provider (Gustafsson et al 2005 ) Customer satisfaction is the main factor that influences customer behavior (Woodside, Frey, and Daly,1989)...
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