p63 basal stem cell hyperplasia toward malignant transformation

Báo cáo y học: "Does the immune reaction cause malignant transformation by disrupting cell-to-cell or cell-to-matrix communications?" docx

... dedifferentiated daughter -cell; the daughter cell is postulated to be more capable of symmetrical division, ie., the old stem- cell is superseded by a new defective -stem- cell that is less subject ... division of stemcells [4] The new, replacement stem- cell might carry accumulated antigenic mutations not present in the superseded immortal strand and thus provide, concurrently with malignant transformation, ... cell- to -cell or cell- to-matrix interactions appear to be major inhibitors [24-26], it seems reasonable to suggest that the mechanism of immunostimulation may be an interference with cell- to-cell...

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Tế bào gốc (Stem cell)

Danh mục: Sinh học

... loại tế bào gốc trưởng thành giai đoạn biệt hóa thấp c/ Tế bào gốc trưởng thành (Adult stem cells/Somatic stem cells): Còn gọi tế bào gốc thân Là tế bào chưa biệt hóa tìm thấy với số lượng mô người ... tế bào gốc thai, tế bào gốc trưởng thành a/ Tế bào gốc phôi (Embryonic stem cells-ESCs) tế bào mầm phôi (Embryonic germ cells) Tế bào gốc phôi tế bào gốc vạn lấy từ phôi giai đoạn sớm (4-7 ngày ... tế bào, mô định Các tế bào gốc phôi lấy từ khối tế bào bên (inner cell mass) tế bào gốc vạn c/ Tế bào gốc đa (multipotent stem cells): Là tế bào có khả biệt hóa thành nhiều loại tế bào thể từ...

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Tài liệu Review of Chronic Graft- Versus-Host Disease in Children After Allogeneic Stem Cell Transplantation: Nursing Perspective pptx

Danh mục: Sức khỏe trẻ em

... common after peripheral blood stem cell transplantation than BMT because it is generally accepted that peripheral blood stem cells con tain greater numbers of infused T-cells (Bishop, 2009; Schmitz ... ALL Myelodysplastic syndrome Relapsed AML Hematological malignancy ALL Malignant and nonmalignant disease Malignant and nonmalignant disease Acute leukemia Pretransplant Disease 904 days years ... Patients (years) Hematological malignancy Malignant and nonmalignant disease β Thalassemia major Leukemia or myelodysplastic syndrome Malignant and nonmalignant disease ALL Myelodysplastic syndrome...

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Tài liệu INNOVATIONS IN STEM CELL TRANSPLANTATION doc

Danh mục: Sức khỏe giới tính

... any cell type A stem cell does not differentiate directly to a specialized cell, however There are often multiple intermediate stages A stem cell will first differentiate to a progenitor cell ... investigating the role of stem cells in cell transplantation or regenerative medicine increased remarkably across all sections of the stem cell related journals The largest number of stem cell articles was ... aspects of stem cells and cell transplantation Although we are close to finding pathways for stem cell therapies in many medical conditions, scientists need to be careful how they use stem cells ethically...

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Tài liệu New Advances in Stem Cell Transplantation Edited by Taner Demirer ppt

Danh mục: Sức khỏe giới tính

... remain a stem cell, or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell Because of the unique abilities of stem cells, as ... Keratinocytes ND ND Neural stem cells

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Guidelines for Human Embryonic Stem Cell Research potx

Danh mục: Cao đẳng - Đại học

... this report are common to other areas of human stem cell research, such as research with adult stem cells, fetal stem cells, or embryonic germ cells derived from fetal tissue Institutions and ... Embryonic Stem Cell Research http://www.nap.edu/catalog/11278.html Introduction Stem cells are capable of self-renewal and also of differentiation into specialized cells Some stem cells are more ... types of cells It is believed that stem cells also form reservoirs of repair cells to replace cells and tissues that degenerate over the life span of the organism The dual capacity of stem cells...

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Báo cáo khoa học: Polypyrimidine tract-binding protein is essential for early mouse development and embryonic stem cell proliferation potx

Danh mục: Báo cáo khoa học

... disruption of Ptb in ES cells Ptb) ⁄ flox ES cells were generated by expression of Cre in Ptb) ⁄ flox-hyg ES cells Ptb) ⁄ ) ES cells were generated by infection of Ptb) ⁄ flox ES cells with a retroviral ... Ptb) ⁄ ) ES cells was reduced as compared with wild-type cells (C) Impairment of cell proliferation seen in the Ptb) ⁄ ) ES cells was rescued by ectopic expression of PTB Ptb) ⁄ ) ES cell clones ... ) ES cells exhibit reduced cell proliferation A Relative gene expression although the expression of a part of ES cell- specific markers was reduced in Ptb) ⁄ ) ES cells, both Ptb) ⁄ ) ES cell clones...

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Autoimmune Diseases – Contributing Factors, Specific Cases of Autoimmune Diseases, and Stem Cell and Other Therapies pdf

Danh mục: Sức khỏe giới tính

... of the infiltrate showed that most cells corresponded to T cells, with T cytotoxic/suppressor cells being most abundant, although helper CD4+ T cells and NK cells Immunologic and Genetic Factors ... of the infiltrating cells is compatible with a cytotoxic T cell mediated beta -cell destruction, it has not yet been proven that the cells in the insulitic lesion are the cells that are actually ... beta -cell- specific CD4+ T helper cells The cytotoxic CD8+ T cells then affect beta -cell damage by releasing perforin and granzyme, and by Fas-mediated apoptosis In this way, macrophages, CD4+ T cells,...

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Commercializing the stem cell sciences pot

Danh mục: Điện - Điện tử

... the stem cell sciences towards long-term goals Several companies are successfully developing with this model, including Stem Cells Inc (http://www stemcellsic.com), Cellartis (http://www.cellartis.com) ... technologies 2.1.2 Stem cell tourism Stem cell tourism is another area that is having a significant impact on the potential market share of stem cell products A form of medical tourism, stem cell tourism ... to cell culturing, eight are related to antibodies and twelve are specific stem cell factors that have been differentiated from both human and mouse stem cells Outside of these products, Stem Cells...

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NGHIÊN CỨU SỬ DỤNG TẾ BÀO GỐC TRUNG MÔ (MESENCHYMAL STEM CELL - MSC) TRONG ĐIỀU TRỊ UNG THƯ ĐẠI - TRỰC TRÀNG TRÊN CHUỘT (SPRAGUE DAWLEY) ppt

Danh mục: Báo cáo khoa học

... potential of mesenchymal stem cells producing interferonalpha in a mouse melanoma lung metastasis model, Stem Cells 26, (2008), 2332-8 Satija, N K et al., Mesenchymal stem cell- based therapy: a ... mesenchymal stem cells in cancer immunotherapy in mice Research results show that the mesenchymal stem cells injected into mice at the dose of 107 cells/ml can inhibit the proliferation of cancer cells ... cell- based therapy: a new paradigm in regenerative medicine, J Cell Mol Med 13, 2009 STEM CELL RESEARCH USING MESENCHYMAL (MESENCHYMAL STEM CELL - MSC) IN THE TREATMENT OF CANCER AGENCY - RECTUM RATS...

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stem cell biology - daniel r. marshak

Danh mục: Sinh học

... Germ-line Stem Cells, 149 Amy A Kiger and Margaret T Fuller Primordial Germ Cells as Stem Cells, 189 Brigid Hogan 10 Embryonic Stem Cells, 205 Austin Smith 11 Embryonal Carcinoma Cells as Embryonic Stem ... transitional cells These cells can commit following expansion as blast cells, or alternatively, stem cells can proliferate as multipotent cells For example, in the hematopoietic system high- Stem Cell ... Epidermal Stem Cells, 439 Fiona M Watt Section V: Endoderm 20 Liver Stem Cells, 455 Markus Grompe and Milton J Finegold 21 Pancreatic Stem Cells, 499 Marcie R Kritzik and Nora Sarvetnick 22 Stem Cells...

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hematopoietic stem cell protocols

Danh mục: Sinh học

... hematopoietic stem cells: in vivo expansion of stem cell phenotype but not function Blood 85, 1006–1016 Li, C L and Johnson, G R (1995) Murine hematopoietic stem and progenitor cells: I Enrichment ... of isolating cells capable of sorting 2–50 × 103 cells/s (1.2–30 × 105 cells/min) The very low frequency (

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university of california press fundamentals of the stem cell debate the scientific religious ethical and political issues dec 2007

Danh mục: Cao đẳng - Đại học

... primitive stem cells, and the stem cells appear to have greater proliferative potential than bone marrow cells In addition, UCB stem cells implant and function as stem cells at lower cell doses ... the ethical issues for stem cell research, stem cell therapy, and stem cell policy development He reviews the several scientiﬁc strategies for obtaining potent human stem cells that have been proposed ... that modiﬁed stem cells could be used in cell therapy for Parkinson’s disease 42 Therapeutic Uses of Stem Cells But, as with other proposed stem- cell therapies, an autologous source of cells that...

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Báo cáo hóa học: " Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke" ppt

Danh mục: Hóa học - Dầu khí

... administration or neural stem cell transplant A: reddish brown coloration of caspase III immunoreactivity along the ventricular lining of cells of ischemic rat having undergone neural stem cell transplant ... bone marrow stem cells in ischemic brain Acta Neurochir Suppl 2006, 99:123-124 Li J, Sun CR, Zhang H, Tsang KS, Li JH, Zhang SD, An YH: Cotransplantation of neural stem cells and Schwann Cells results ... in the lesioned micro-environment of the CNS Materials and methods Culture of Neural stem cells Neural stem cells were harvested from the cortex of E16 Sprague-Dawley rat embryos The head was...

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Báo cáo sinh học: " Risk factors in the development of stem cell therapy" pdf

Danh mục: Hóa học - Dầu khí

... accompanied by cell sorting to minimise the number of pluri/ multipotent stem cells in the cell preparation [86], or to separate tumourigenic stem cells from non-tumourigenic stem cells (by e.g cell sorting ... cultured cells, including stem cells These risk factors are not unique to stem cells and apply to all cell based medicinal products Donor history is of particular importance for stem cell lines ... Approach for the Generation of Induced Pluripotent Stem Cells Cell Stem Cell 2008, 2:525-528 81 Uccelli A, Moretta L, Pistoia V: Mesenchymal stem cells in health and disease Nature Reviews Immunology...

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Báo cáo sinh học: "Cancer stem cell subsets and their relationship" pot

Danh mục: Hóa học - Dầu khí

... precancerous stem cells undergo the transformation from normal stem cells to primary cancer stem cells Precancerous lesions progress to cancer when precancerous stem cells transform into primary cancer stem ... a type of precancerous stem cells from dendritic cell- like leukemic mice and the establishment of this precancerous stem cell line The precancerous stem cells had stem cell- like phenotype, unlimited ... cancer stem cells initiate from; whether primary cancer stem cells are same in the same type of cancer among different patients; and how to distinguish cancer stem cells from normal stem cells...

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Báo cáo sinh học: "Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction" ppt

Danh mục: Hóa học - Dầu khí

... availability of various cellular sources for experimental investigations [6,7,10-15] including bone marrow-derived mesenchymal stem cells (BMDMSCs), hematopoietic stem/ progenitor cells, and cells of embryonic ... adipose-derived mesenchymal stem cells (ADMSCs) After culturing for 14 days, majority of isolated adipose-derived stem cells expressing CD29 and CD90 characteristic of mesenchymal stem cells (n = 3) Note ... have emphasized stem cell therapy as an effective treatment modality for acute kidney injury, the mechanistic basis underlying the observed improvement in renal function after stem cell therapy...

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báo cáo hóa học:" Cancer stem cell subsets and their relationships" pot

Danh mục: Hóa học - Dầu khí

... precancerous stem cells undergo the transformation from normal stem cells to primary cancer stem cells Precancerous lesions progress to cancer when precancerous stem cells transform into primary cancer stem ... a type of precancerous stem cells from dendritic cell- like leukemic mice and the establishment of this precancerous stem cell line The precancerous stem cells had stem cell- like phenotype, unlimited ... cancer stem cells initiate from; whether primary cancer stem cells are same in the same type of cancer among different patients; and how to distinguish cancer stem cells from normal stem cells...

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