hallucinogens club drugs marijuana cannabis and inhalants
báo cáo khoa học: " Long term marijuana users seeking medical cannabis in California (2001–2007): demographics, social characteristics, patterns of cannabis and other drug use of 4117 applicants" docx
... Management Business and Financial Operations Computer and Mathematical Architecture and Engineering Life, Physical, and Social Science Community and Social Service Legal Education, Training and Library ... Sports and Media Healthcare Practitioner and Technical Healthcare Support Protective Service Food Preparation and Service Related Building and Grounds Cleaning and Maintenance Personal Care and ... Service Sales and Related Office and Administrative Support Farming, Fishing and Forestry Construction and Extraction Installation, Maintenance And Repair Production Transportation and Materials...
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Detection of Antiviral Drugs Oseltamivir Phosphate and Oseltamivir Carboxylate in Neya River, Osaka, Japan
... influenza pandemic and drastic increase in antiviral drugs consumption It is therefore worthy to monitor the drugs in surface waters in the winter season to get more insight of whether the drugs really ... these drugs during the period of seasonal influenza and H1N1 influenza pandemic (September 2009 to February 2010) MATERIALS AND METHODS Chemicals and Reagents Oseltamivir phosphate (CAS-RN: 204255-11-8) ... the sampling stations and dates are illustrated in Table The stations along the river extend between 34º 40’ 45.75"N and 34º 46’ 13.96"N latitudes, and 135º 28’ 3.42"E and 135º 36’ 40.44"E longitudes...
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Báo cáo khoa học: Modulation of heme and myristate binding to human serum albumin by anti-HIV drugs An optical and NMR spectroscopic study potx
... Modulation of HSA ligand binding by anti-HIV drugs G Fanali et al Fig Binding isotherms for Fe(III)heme binding to HSA (FA free) and to HSA–myristate complexes in the absence of drugs (A) and presence ... showing that all FA7 ligands reduce the affinity of heme by one order of magnitude and, Fig Superimposition of Fe(III)heme and abacavir (A) and nevirapine (B) in binding site FA1 Ligands are coloured ... anti-HIV drugs G Fanali et al Fig NMRD profiles of Fe(III)heme–HSA (FA free) and Fe(III)heme–HSA–myristate complexes in the absence of drugs (A) and in the presence of abacavir (B), nevirapine (C) and...
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PEGylated Protein Drugs: Basic Science and Clinical Applications pptx
... drugs, including, antibodies, peptides and proteins, polymer therapeutics, and oligonucleotides and cell therapy will all play an important and complementary role in the prevention, control and ... able to diagnose and then deliver even macromolecular drugs, so-called theranostics, and to design systems able to promote tissue regeneration and repair in disease, trauma, and during ageing ... Duncan and F.M Veronese cells, and promotion of tissue engineering and repair, design of systems that self-assemble in the patient, and to fabrication of hybrid systems combining DDS technologies and...
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Section V - Drugs Affecting Renal and Cardiovascular Function doc
... Na +–H+ and Na+–Ca2+ antiporters and inhibits the Na+ pump Absorption and Elimination The relative potency, oral bioavailability, plasma half-life, and route of elimination for amiloride and triamterene ... possible and is used in this chapter Diuretics not only alter the excretion of Na+, but also may modify renal handling of other cations (e.g., K+, H+, Ca2+, and Mg2+), anions (e.g., Cl–, HCO3–, and ... infrequent; however, these drugs are sulfonamide derivatives and, like other sulfonamides, may cause bone-marrow depression, skin toxicity, and sulfonamide-like renal lesions and may cause allergic...
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Unit 6: The young pioneers club Getting started, Listen and read pdf
... their books to - Collecting and empting garbage look at the activities that the Y & Y - Planting trees and flowers participate in and check () the - Watering tree and flowers boxes Call Sts to ... is enrolling for the Call some Sts to give their a English speaking club answers b English writng club Ask Sts to listen again and check c Activities for this their answers summer T gives the key ... meanings trời Sts copy down hobly: (n) sở thích T checks (Rub out and remember) drawing: (n) tranh vẽ, việc vẽ tranh Sts listen and repeat fill out: (n) điền (vào chỗ trống) b) Set the scence of...
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Báo cáo y học: "Primary care use of antipsychotic drugs: an audit and intervention study" ppt
... consent for AM and CS to administer ratings of symptoms, side effects, general function and quality of life The current medication regime and the patients' general mental health and well-being ... anxiety symptoms, restlessness and a tremor of several months' duration He was advised to reduce and stop his chlorpromazine and procyclidine over a three month period, and reduce the dose of lithium ... these medications and his tremor was much reduced His GP had started a small dose of buspirone, and his anxiety and general mood were much improved He was much more socially active and was attending...
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Báo cáo y học: "Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways" ppsx
... (LTβ) and CD40 ligand, and mediates the processing of NF-κB complex to p52/RelB [25,26] This IKK complex then phosphorylates p100 at C-terminal domain and promotes the ubiquitination of p100 and ... cyclin dependent kinases (CDKs) and 6, cyclin D2, and CDK inhibitors p21waf1 and p16INK4A [51-57] Tax expression also results in transcriptional activation of cyclin E and CDK2 complex [58-61] In ... tested Collectively, understanding the inhibition mechanism, efficiency and the combined effects of both BMS-345541 and Purvalanol A will help gain better insights and establish novel new therapeutic...
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báo cáo khoa học: " Cannabis as a substitute for alcohol and other drugs Amanda Reiman" pps
... symptoms; access and level of acceptance The substitution of cannabis for alcohol and other drugs has been observed among individuals using cannabis for medical purposes Medical cannabis patients ... medical information, cannabis use pattern, alcohol and drug use and service utilization Participants were asked the quantity and frequency of alcohol, tobacco and drug (prescription and illicit) use ... well as current and past alcohol and/ or drug treatment Participants were also asked about whether they use cannabis as a substitute for alcohol, illicit drugs or prescription drugs and why to investigate...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 17)
... 0.05 mL of isobutyl nitrite or isobutyl alcohol standard solution at various concentrations and 0.2 mL distilled water are placed in the vial and mixed The following procedure is exactly the same ... µg) and isobutyl alcohol (injected amount 10 µg); they appeared at 3.4 and 7.4 of retention times, respectively The solvent acetone appeared at about The detection limits of isobutyl nitrite and ... nitrite (A) and isobutyl alcohol (B) um between the hydrolysis and esterification [7] Under the present HS conditions, the decomposition of alkyl nitrites by hydrolysis is minimized, and the esterification...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 67)
... in environmental and biological samples using gas chromatography/negative-ion chemical ionization mass spectrometry and tandem mass spectrometry J Mass Spectrom 30:1133–1143 VX and its decomposition ... NaCl and mL acetonitrilei, shaken and centrifuged The resulting acetonitrile layer is transferred to another test tube To the remaining aqueous phase, mL acetonitrile is again added, shaken and ... metabolism and decomposition in human bodies The detection limits of DAEMS in serum are about 50 ng/mL in the scan mode and about ng/mL in the SIM mode > Figure 2.3 shows a TIC, mass chromatograms and...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 20)
... 188 Cannabinoids and their metabolites GC analysis of cannabinoids in plant specimensa Reagents and their preparation • • • Extraction and purification of cannabinoids [3]: Cannabis sativa L ... d3- and d10- substitution products of the acid are used When ∆9-THC11-oic acid-d3 is used, the mass spectrum shows ions at m/z 433, 418 and 374 with the Derivatization-2, and at m/z 491, 476 and ... for analysis of cannabis and its components In: The Pharmaceutical Society of Japan (ed) Standard Methods of Chemical Analysis in Poisoning – With Commentaries, 4th edn., Nanzando, Tokyo, pp...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 21)
... morphine, heroin and codeine The thick and thin arrows show the main and minor metabolic pathways, respectively ⊡ Figure 3.1 196 Morphine and its analogues GC and GC/MS analysis • • • • • Standard solutions ... HPLC analysis Reagents and their preparation • • Standard solutions of morphine for a calibration curve (2, and 20 µg/mL): see “Reagents and their preparation”, above of GC and GC/MS analysis section ... urine specimen obtained from a healthy subject and the urine specimens spiked with 0.1 mL each of the standard solutions (2, and 20 µg/mL) are also handled in the same way as above ii Each of the...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 70)
... wide-bore and medium-bore capillary columns With the medium-bore capillary column, a big and broad peak due to mesitylene appears The detection limits are about 0.3 and 0.1 µg/mL for wide-bore and ... addition of 0.5 mL of concentrated sulfuric acid f and 0.5 mL of mesitylene Nitrate and nitrite compounds iv The mixture is vortex-mixed for and centrifuged at 3,000 rpm for v A 0.2-mL volume ... cyanosis headache, dyspnea, tachypnea, tachycardia and hypertension mental derangement, listlessness and metabolic acidosis coma, convulsive attack and hypotension death A poisoning case [4] An unidentified...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 71 and End)
... B, C and D v To cuvettes A and B, a 0.5-mL volume each of distilled water is added To cuvettes C and D, a 0.5-mL volume each of % potassium ferricyanide solution is added vi To cuvettes A and ... allowing the cuvettes to stand for min, the absorbances of cuvettes B and D at 630 nm are read using cuvettes A and C as references, respectively These readings are A2 and A4, respectively x The ... S-2-diisopropylaminoethyl methylphosphonothiolate 619 OHMA 181 OHnorBZP 171, 179, 183 oleandrigenin 519 oleander poisoning 524 oleander toxins 519 oleandrin 519, 521, 523, 525 on-column derivatization 238 on-column...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 22)
... sampling, and processed for extraction and derivatization procedure Good recoveries of cocaine and its metabolites can be obtained with a mixed type extraction column (Bond Elut Certify®) and a diatomite ... solution; EME and BE, 10 mg each, are dissolved in 100 mL methanol respectively These stock solutions are appropriately diluted just before use to serve for standard solutions As internal standard (IS) ... recoveries with simple procedure and thus is useful in forensic toxicology Cocaine and its metabolites a) Procedure I (Bond Elut Certify®) [6–8] i Extraction from urine and derivatization A 5-mL volume...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 23)
... 214 and at m/z 285 (M+) plus 217 were used for detection of IS and pentazocine, respectively When SIM with a single ion is made, ions at m/z 217 and 271 (M+) should be used for pentazocine and ... cases of pentazocine poisoning, its concentrations were 9.2 and 3.3 µg/mL in blood, 43 and 34 µg/g in the liver, and not detectable and 4.5 µg/mL in urine, respectively [12] The blood concentrations ... and tripelennamine, T,s and Blues J Forensic Sci 28:489–495 3) Kintz P, Tracqui A, Lugnier AJ et al (1990) Simultaneous screening and quantification of several nonopiate narcotic analgesics and...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 24)
... (ed) (1992) Standard Methods of Chemical Analysis in Poisoning – With Commentary – Nanzando, Tokyo, p 43 and p 151 (in Japanese) 3) Cody JT (2000) Hallucinogens In: Bogusz MJ (ed) Handbook of Analytical ... described for seized items, and not for human specimens It is actually not easy to detect LSD from blood and urine, because its amount to be ingested is as small as about 10 µg and LSD is rapidly metabolized ... of LSD, 2-oxo-LSD, 3-, 13- and 14-hydroxy-LSDs and an N-de-ethyl-LSD are known [3] After oral ingestion of 160 µg LSD, the maximum blood concentration of LSD was ng/mL and its half-life is said...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 25)
... designer drugs Biochem Pharmacol 59:1563–1571 Symptoms, and toxic and fatal concentrations 9) Pizarro N, Ortuño J, Farré M et al (2002) Determination of MDMA and its metabolites in blood and urine ... Substance Abuse and Mental Health Services Administration (SAMHSA) is 250 ng/mL Symptoms, and toxic and fatal concentrations MDMA causes increased catecholamine (including serotonin) release and blockade ... cerebrovascular disorders, and drug-related accidents or suicides The effects of other MDAs are similar to those of MDMA Symptoms, and toxic and fatal concentrations ⊡ Table 7.2 Acute and chronic effects...
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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 26)
... fluid, vitreous humor and urine than in blood Villain et al [21] and Elliott [31] have tentatively set positive cutoff limits of GHB at 50 and 30 µg/mL for postmortem blood, and 10 and 20 µg/mL for ... (PCP) and at m/z 246 plus 232 plus 218 (IS) were used at the retention time of 4–12 The amounts of PCP and IS spiked into mL blank whole blood were 25 and 100 ng, respectively Poisoning case, and ... PCP and IS In this method, combined ions at m/z 242 ([M–1]+) plus 200 and those at m/z 246 ([M–1]+) plus 232 plus 218 are used for PCP and IS, respectively The mass chromatograms of PCP and IS...
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