genetics and genomics susceptibility to stress
báo cáo khoa học: "BRAD, the genetics and genomics database for Brassica plants" ppt
... helping scientists and breeders to fully and efficiently use the information of genomics and genetics datasets of Brassica plants, BRAD will continuously improve its applications and integrate more ... and A thaliana were obtained, and there were 9, 293, 6, 683 and 2, 346 A thaliana genes which have 1, and paralogous copies in the B rapa’s subgenomes LF, MF1, and MF2, respectively LF, MF1 and ... as shown in Figure Tools BLAST and Genome browse (Gbrowse) are embedded to help users mine and visualize the genome data 1) BLAST We utilized the standard wwwblast modules to help users perform...
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báo cáo khoa học: " Measuring cis-acting regulatory variants genome-wide: new insights into expression genetics and disease susceptibility" pdf
... ribosomes and translation Figure Schematic representation of the detection of cis- and transregulatory variants and the type of polymorphisms involved in gene expression eQTL mapping and expression ... essential to tackle these complex interactions The way forward: how we identify regulatory variants germane to fitness and disease The results of Ge et al [5] significantly advance our under standing ... that provide human autopsy tissues from diseased subjects and controls that are suitable for AE analysis Also, SNP scanning and subsequent molecular genetics studies are needed to identify the polymorphisms...
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Báo cáo y học: "Immunodepression in the surgical patient and increased susceptibility to infection" doc
... factor (quantitative flow cytometry, allowing counting of molecules per cell), and T-cell cytokine profiling (differentiation of type 1/2 cytokine patterns by intracellular cytokine staining and ... well standardized assays for detecting monocytic cytokine secretion (whole blood assay with semi-automatic cytokine measurement), monocytic HLA-DR and CD86 expression Figure IL-10 TGF-b LPS Stress ... infection) leads to a strong and long-lasting activation of the immune deactivating stress axis, which increases susceptibility to infection In addition, high levels of corticosteroids and catecholamines...
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Báo cáo y học: "Genetics and genomics converge on the human blood fluke" potx
... and female F1 cercariae are then mixed and used to infect a hamster to produce the F2 Adapted from [17] mate, the fertilized eggs are shed in the feces of the infected hamster and develop into ... sensitivity to the main anti-schistosome chemotherapeutic, praziquantel [15], and variation in the ability to infect different strains of the snail host [16] And now such variation is amenable to analysis, ... informative polymorphic microsatellite markers and used them to genotype 88 F2 progeny and their parents The markers were deliberately targeted to different contigs to ensure they were physically separated,...
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Tài liệu Báo cáo khoa học: Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion pptx
... cell susceptibility to Yersinia invasion Yersinia virulence factors are injected into target host cell molecules to manipulate signalling pathways during invasion in order to prevent uptake and ... PAGE gel and Coomassie Blue staining, and the band corresponding to a modified OTUB1 (rectangle) was excised and digested with trypsin The peptide mixture was analysed by a nano-UPLC-QTOF tandem ... increased binding to YpkA Mimicry of OTUB1 phosphorylation modulates susceptibility to Yersinia invasion If the interaction between OTUB1 and YpkA were relevant for increased susceptibility to invasion,...
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Tài liệu Static and Dynamic Analysis of the Internet’s Susceptibility to Faults and Attacks docx
... leading to the creation of new Internet topology generators Tangmunarunkit et al divide network topology generators into two categories [38]: Structural and Degree-Based network generators Other ... network topology and that building an effective topology generator is at least as important as protocol simulations Previously, the Waxman generator [35], which is a variant of the Erdos-Renyi random ... method to simulate network protocols is using the real Internet topology instead of using Internet topology generators, which innately limits our ability to develop, for example, network protocols...
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Báo cáo khoa học: The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs pdf
... localizes to the nucleus and cytoplasm and, upon environmental stress, concentrates in stress granules The novel ROQ domain mediates localization to stress granules and induces spontaneous stress ... Roquin localizes to stress granules and binds RNA in the ability to induce stress granules and importantly was not recruited to TIA-positive stress granules even in stressed cells (Figs and S3D) By ... transiently stored and rerouted to polysomes to be translated [17] P-bodies are highly mobile within the cytoplasm, intermittently attaching to stress granules [14] Factors such as the cytoplasmic...
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Báo cáo khoa học: Tumor suppressor p16INK4a ) modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells ppt
... cancer and normal tissue revealed differential gene activities, especially up-regulation for b4GalT-V (factor 9.91) and b4GalT-I (factor 2.54) and an inverse regulation for GnT-IVa and b (factors ... p16INK4a-positive cells and the mentioned SK-N-MC neuroblastoma model It is reactive, too, with other carcinoma cells [28] and was related to differentiation and apoptosis after its expression ... route towards re-establishing susceptibility for anoikis The presented results lend credit to a scenario of finetuned and co-ordinated events translating into alterations of protein–protein and...
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Báo cáo khoa học: Differential susceptibility of Plasmodium falciparum versus yeast and mammalian enolases to dissociation into active monomers doc
... Mim and MpH differ in activity and stability from the dimer and Mnt MpH is rapidly converted into Mnt on raising of the pH, whereas Mim is slow to convert to Mnt, a form that is competent to form ... 19.3% and random 29.9% for the dimeric form, and helix 31.5%, beta 18.3%, turn 18.4% and random 31.8% for the monomeric form Thus, it appears that dissociation of dimers to form monomers lead to ... bound to one and two Mg(II) ions exhibits both types of hydrogen bond The subunit bound to one Mg(II) ion has a hydrogen bond between His189 and Arg14, and the other subunit, which is bound to two...
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Plant reproductive susceptibility to habitat fragmentation: review and synthesis through a meta-analysis pptx
... trees; Vi, vines), and habitat type (Bo, boreal; Gr, grassland; Shl, shrubland; Te, temperate; Tp, tropical) Reviews and Syntheses Reproductive susceptibility to fragmentation 973 to the 95% bias-corrected ... differential reproductive susceptibility of plants to habitat Reproductive susceptibility to fragmentation 969 fragmentation in relation to their compatibility systems and degree of pollination ... interact with both generalist and specialist pollinators, would tend to loose their specialist pollinator fraction from their assemblages and retain their generalist pollinators Thus, decreases in...
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Stress and Performance - A Review of the Literature and Its Applicability to the Military pdf
... moderators may affect the relationship between stress and performance: one moderator point occurs between stressor and stress response and the other between stress response and performance Stressor ... Stress and Decisionmaking, Perception, and Cognition 17 Stress and Group Functioning 19 Stress and Job Satisfaction and Turnover Intentions 20 Long-Term Effects of Stress 21 Moderators ... Mandler’s psychological results of stress as part of the performance effects of stress and use the term stress to refer only to the physiological response Figure 1.1 represents the stressor-stress...
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Báo cáo khoa học: Specific TSC22 domain transcripts are hypertonically induced and alternatively spliced to protect mouse kidney cells during osmotic stress pptx
... [59], TonEBP transcription factor [46] and aquaporin [61] in response to hypertonicity mRNA stabilization is a regulatory mechanism involved in rapid responses to various forms of cellular stress, ... tolerance to hyperosmotic stress in mIMCD3 cells (A) Representative images of transfected and control (FRT) cells after exposure to 600 and 650 mOsm for 24 h (B) Count of viable transfected and ... glycine-betaine, myo-inositol, taurine, sorbitol, and glycerophosphorylcholine [2–4] Accumulation of glycine-betaine, inositol, and sorbitol is transcriptionally regulated and depends, at least in...
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introduction to molecular genetics and geonomics - hearts
... 09131_01_1677P Photocaptionphotoca ptionphotocaptionphotocaptionphotocaptionphotocaptionp hotocaptionphotocaptionphotocaptionphotocaptionphotocaption photocaptionphotocaptionphotocaptionphotocaptionphotocap ... paired strands of a DNA molecule, if one strand has an A, then the partner strand has a T; and if one strand has a G, then the partner strand has a C The pairing between A and T and between G and C ... Introduction to Molecular Genetics and Genomics 1.8 Evolution: From Genes to Genomes, from Proteins to Proteomes The pathway for the breakdown and excretion of phenylalanine is by no means unique to human...
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báo cáo hóa học: " Occurrence of post traumatic stress symptoms and their relationship to professional quality of life (ProQoL) in nursing staff at a forensic psychiatric security unit: a cross-sectional study" potx
... forensic psychiatry and the relationship between, and occurrence of job satisfaction, burnout and post traumatic stress symptoms has not been explored The aim of this present study is to explore relations ... scale to rate the extent to which they had been bothered in the past month by 17 symptoms of post traumatic stress based on the DSM-IV symptom clusters: reexperiencing, avoidance/numbing, and arousal ... symptoms tend to stay at a ward with high structure and less need for engagement in patients rehabilitation The long experience of these nurses leads both to a higher exposure to violence, and...
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Báo cáo hóa học: " Application of functional genomics to the chimeric mouse model of HCV infection: optimization of microarray protocols and genomics analysis" potx
... software and all data was then entered into a custom-designed database, Expression Array Manager, and then uploaded into Rosetta Resolver System 4.0.1.0.10 (Rosetta Biosoftware, Kirkland, WA) and ... extraction kit (Qiagen), cloned into pCR4 TOPO according to manufactures specifications (Invitrogen) and sequenced The cloned fragments from mouse and human were 452 bp and 384 bp, respectively For ... response to IFN therapy [9], and identifying potential markers of HCVassociated liver disease [10,11] The use of functional genomics to study chimeric systems, such as those used to study HCV and...
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Physiological and biochemical responses to salt stress in the mangrove pptx
... attributable to a reduction in stomatal opening The likely sequence of events was thought to be increased salinity, water stress, stomatal closure, decrease in intracellular CO2 , and decrease in photosynthesis ... CO2 influx to match the photon flux We were unable to find such major differences in salt concentration between xylem sap and medium as those reported by Scholander and co-workers (Scholander et ... layer of oil to prevent evaporation, and its level was monitored over 140 h These experiments were conducted in the culture room at 25◦ C, and a 12 h photoperiod Water was added as needed to prevent...
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Báo cáo khoa học: "Scots pine susceptibility to attack by Tomicus piniperda (L) as related to pruning date and attack density" pps
... was stable during the procedure and close to the standard 15 °C (up to the first living whorl at m height) transported to the laboratory within 24 h, and cold-stored at +2 °C until the next day ... capacity to translocate carbohydrates to the area under attack (Christiansen and Ericsson, 1986; Miller and Berryman, 1986; Långström et al, 1992) Hence, manipula- tion of needle biomass and tree ... of the total sapwood area; see Waring and Pitman, 1980; for a discussion of the underlying physiological assumptions, see Waring and Pitman, 1985), and sapwood percentage were calculated and used...
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Báo cáo y học: "Higher susceptibility to Fas ligand induced apoptosis and altered α modulation of cell death by tumor necrosis factor-α in periarticular tenocytes from patients with knee joint osteoarthritis" ppt
... Apoptosis is a physiological process and is a highly selective way to eliminate aged and injured cells In addition to internal pathways that trigger apoptosis mainly in response to cytotoxic stress, ... the apoptosis-inducing receptor Fas in periarticular tenocytes of patients with OA and studied their susceptibility to apoptosis in the presence or absence of recombinant human FasL and TNF-α ... regulation of cell growth and apoptosis in tenocytes under normal conditions and in degenerative diseases, such as OA Changes in apoptotic pathways appear to be of importance to the pathogenesis of...
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Báo cáo lâm nghiệp: "Variations in seed and seedling responses to water stress in three provenances of Eucalyptus camaldulensis Dehnh" pptx
... Dwt/kg water) and by carbon discrimianalysis (Farquhar and Richards, 1984) was significantly largest in water- nation stressed, fertilised Tennant Creek seed- Both water and nutrient stress caused ... leaves to become more linear (as opposed to lanceolate) in shape Principal component analysis (Cooley and Lohnes, lings (Fig 3) Water stress reduced leaf area most in Katherine seedlings (Fig 4), and ... provenances also differed in stress- induced changes in the partitioning of dry matter into roots, stems and leaves (Fig 5) Stressed Tennant Creek seedlings allocated more dry matter into leaves at the expense...
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Báo cáo y học: "Regulatory polymorphisms in extracellular matrix protease genes and susceptibility to rheumatoid arthritis: a case-control study" ppsx
... plasminogen activator, tissue type (PLAT) [17] and plasminogen activator inhibitor-1 (PAI-1) [18] They were selected as appropriate candidates to participate in RA susceptibility and studied in ... associated with susceptibility to, and severity of, chronic periodontitis J Periodontol 2005, 76:1056-1060 Mercado FB, Marshall RI, Bartold PM: Inter-relationships between rheumatoid arthritis and periodontal ... sample donors for their collaboration and Drs Antonio Mera, Manuel Caamaño, Jorge Blanco and Santos Insua for providing access to their patients Lorena Fernandez-Blanco collaborated in the selection...
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