from the customer domain to the functional domain
Tài liệu Báo cáo khoa học: Mapping the functional domains of human transcobalamin using monoclonal antibodies pptx
... mAbs on the functional properties of TC (this study, [16]) supplemented the epitope mapping and provided a deeper insight into operation of the TC domains The binding of TCặCbl to the receptor was ... Arrows show the hypothetical movement of the domains after attachment of Cbl, see the main text of the receptor related domains to the epitope clusters 2, [GQLAQYGL(103159)] and the heparin binding ... lower panel) Neither of the latter mAbs attached to the separated peptides 10 and 11 as follows from the absence of the corresponding bands on the western blot Antibodies from the third group...
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báo cáo hóa học:" Cross-diagnostic validity in a generic instrument: an example from the Functional Independence Measure in Scandinavia" docx
... procedure The first step in analysing the psychometric quality of the FIM™ motor items in the present study was to examine the use of the rating scale in each diagnosis, together with the hierarchical ... used to calculate reliability The interpretation is similar to Cronbach's ά The PSI and indicates the degree to which the scale can separate patients into discrete groups A value of 0.7 is the ... units When the observed response pattern coincides with or does not deviate too much from the expected response pattern, then the items constitute a true Rasch scale [14] Test of fit to the Rasch...
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Báo cáo hóa học: " Research Article Sparse Approximation of Images Inspired from the Functional Architecture of the Primary Visual Areas" doc
... contours of the filters in the Fourier domain The Fourier domain origin (DC component) is located at the center of the inset and the highest frequencies lie on the border (b) Real part of the ... (G(s,r) )(s,r) where s is the scale which ranges from to for edge extraction and denoising (and from to for compression) and r indexes the orientations ranging from to The scheme also includes ... applied From the largest to the smallest the insets correspond respectively to the 2nd, 3rd, 4th, low-pass and 5th scale The first scale is not represented (c) Remaining coefficients after the inhibition...
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An investigation into linguistic features of participants in the processes in english and vietnamese from the functional grammar aspect
... choose to research on the topic “An 1.3 Scope of the study Because of the limitation of time, the thesis limits itself to a subarea of functional grammar, the transitivity system, of which the study ... only we provide the learners with the use their knowledge in both fields to help the work easier To master theory but also with the practice It is because of the fact that our aim the function ... participants’name is rather complex We have to pay attention to the Within the scope of a master thesis we cannot cover all the relationship between the participants and the Process (Verb) The features...
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Tài liệu Báo cáo khoa học: Molecular modeling and functional characterization of the monomeric primase–polymerase domain from the Sulfolobus solfataricus plasmid pIT3 doc
... and the b9 strand to the b10 strand at the bottom of the Zn-stem loop in the pRN1 prim–pol structure However, because the Zn-stem loop is a fairly self-standing structure protruding from the ... interface between the DNA binding and the active site subdomains, we managed to model the entire domain without it Another significant finding concerns the nature of the acid residues within the active ... absent from the pRN1 prim–pol domain or slightly different from those occurring therein These differences may account for the fairly different functions performed by the prim–pol domain of the pIT3...
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Báo cáo khoa học: Common mode of DNA binding to cold shock domains Crystal structure of hexathymidine bound to the domain-swapped form of a major cold shock protein from Bacillus caldolyticus pot
... the domain- swapped structure, the first b sheet of The Bc-Csp domain swap provides insight into the folding and misfolding of the CSP The Bc-Csp domain swap occurs in the middle of loop L34 and is ... rotations of their main chains at Glu36w, causing the Bc-Csp structures to open up and allowing them to re-associate as domain- swapped dimers Apart from differences in the course of the protein ... at the point of transition, in the swapped dimer the overall structure of the functional units is not altered significantly as compared to the closed monomers in state and In the open state, the...
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Báo cáo khoa học: "The C-terminal variable domain of LigB from Leptospira mediates binding to fibronectin" pptx
... (RT) for h Then, the Leptospira (10 ) were added to each well and further ino cubated at 37 C for h To determine the inhibition of Leptospira binding to the MDCK cells by Fn, the Leptospi7 o (10 ... to block the attachment of Leptospira, by approximately 47%, when the Fn treated Leptospira were added to the MDCK cells (Fig 1E) Thus, Fn appears to mediate the attachment of Leptospira to the ... control) prior to addition to the MDCK cells (106) Un-treated Leptospira was used as a negative control The binding of Leptospira to ECMs or Fn or the adhesion of Leptospira to the MDCK cells...
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Tài liệu Báo cáo khoa học: Accessibility changes within diphtheria toxin T domain when in the functional molten globule state, as determined using hydrogen⁄deuterium exchange measurements pdf
... toxin is cleaved by furin into two fragments: the A chain corresponding to the catalytic domain (C domain) ; and the B chain corresponding to the translocation domain (T domain) and the receptor-binding ... in the endosome triggers a conformational change, leading to insertion of the toxin in the membrane The C domain is then translocated across the endosomal membrane into the cytosol The C domain ... corresponds to the functional state, which initiates the translocation of the catalytic domain Here, the data allowed identification of the core of the protein in the N state and the evolution of the overall...
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Tài liệu Báo cáo khoa học: Mapping the functional domain of the prion protein docx
... the SOD activity We determined that the active site consists of two domains The first includes the Cu-binding domain and the second includes the conserved hydrophobic domain in the middle of the ... On the basis of the results with antibodies, a series of PrP mutants were made to assess whether deletions of certain domains of the protein decrease the SOD-like activity of the protein The domains ... antibodies that bind to the C terminus of the protein (145–231) The affinity of these antibodies is sensitive to the conformation adopted by the protein Antibody name Epitope Ability to Inhibit Activity...
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Báo cáo khóa học: Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus A member of a novel protein family related to protein disulfide-isomerase doc
... all the proteins Both the wild-type PfPDO and the mutant C35S were active in the insulin reductase assay [23], whereas the activity of the mutant C146S and the double mutant was similar to the ... such as Aquifex and Thermotoga; in fact their proteins show greater similarity to archaeal than to bacterial homologs [53] The reality of horizontal gene flow from archaea to thermophilic bacteria ... and insulin The reaction was started by the addition of mM dithiothreitol to both cuvettes Increasing turbidity from precipitation of the insulin B chain was recorded at 650 nm The stock solution...
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Báo cáo khoa học: NMR studies on the interaction of sugars with the C-terminal domain of an R-type lectin from the earthworm Lumbricus terrestris pot
... chromatography analysis [24] For other sugars, the first signal corresponding to the unbound state began to broaden at [sugar] ⁄ [EW29Ch] 0.5, the center of the broadened signals shifted to the ... state and the sugar-bound state were observed for some residues in the a subdomain owing to lactose contamination from affinity chromatography using lactose– agarose The final product contains the full-length ... site for b-Me-Gal was the same as that for lactose; and (d) the STD–NMR data in this study showed that the epitope of lactose for EW29Ch is the galactose residue Thus, these results showed that...
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Báo cáo sinh học: " Characterization of the protease domain of Rice tungro bacilliform virus responsible for the processing of the capsid protein from the polyprotein" docx
... represented the viral protease [20] Furthermore, the antiserum was used to label virus particles, and revealed that the label was attached to virions The characterization of PR domain, and the immunodetection ... releasing of the coat protein from the polyprotein P3 In vitro releasing of the coat protein from the polyprotein P3 Autoradiography of an SDS-PAGE of induced peptides from different pET-vectors induced ... Numbers over the alignment indicate the alignment length Secondary structure elements from the RSV sequence are represented over the alignment The numbering of the elements follows the RSV numbering...
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báo cáo hóa học:" Characterization of the protease domain of Rice tungro bacilliform virus responsible for the processing of the capsid protein from the polyprotein" ppt
... represented the viral protease [20] Furthermore, the antiserum was used to label virus particles, and revealed that the label was attached to virions The characterization of PR domain, and the immunodetection ... releasing of the coat protein from the polyprotein P3 In vitro releasing of the coat protein from the polyprotein P3 Autoradiography of an SDS-PAGE of induced peptides from different pET-vectors induced ... Numbers over the alignment indicate the alignment length Secondary structure elements from the RSV sequence are represented over the alignment The numbering of the elements follows the RSV numbering...
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Báo cáo y học: "Electrophoretic characterization of species of fibronectin bearing sequences from the N-terminal heparin-binding domain in synovial fluid samples from patients with osteoarthritis and rheumatoid arthritis" doc
... corresponding to the 120- to 140-kDa central cell-binding domain (CBD), the 50-kDa gelatinbinding domain (GBD), and the 40-kDa C-terminal HBD have each been observed to trigger release of proteoglycans from ... species of FN to regulate chondrocyte function may be related both to its capacity to be recognized by cell-surface receptors and to its ability to bind to other components of the extracellular ... binding specificities for various domains and structural motifs shown at the bottom The primary FN sequence extends from the amino (N) terminus (NH2, left) to the carboxy (C) terminus (COOH, right)...
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Báo cáo y học: "Antiviral activity of a-helical stapled peptides designed from the HIV-1 capsid dimerization domain" pps
... not to interfere with the binding of this modified stapled peptide to the CTD monomer We further modified other residues at the Nand C-termini based on the thermodynamic dissection analysis of the ... isolates The cytotoxicity of the stapled peptides was assessed by the XTT method in both MT-2 cells and PBMC Cytotoxicity assays were performed in parallel with the HIV-1 inhibition assays The CC ... CTD complexed with the peptide NYAD-203 The three panels display the effect of the titration on select crosspeaks from the aliphatic region through the titration Resonances from the protein that...
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Báo cáo y học: "introduction to special issue on Eye and Zoonosis – from the guest editors"
... ocular toxoplasmosis Am J Ophthalmol 2008;146:851-5) • Optical Coherence Tomography in ocular toxoplasmosis • Usefulness of vitrectomy in the treatment of ocular toxoplasmosis • Update on the treatment ... ocular toxoplasmosis We hope that this special issue will be interesting to readers and provides researchers with timely update on various topics in this important field Conflict of Interest The...
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Certain issues from the perspective of applying the Communicative Language Teaching to the teaching of oral English in HaUI
... stimulate the students to volunteer to speak, and the passive students need the teacher’s attention They have to be appointed to speak The easy questions should be given to the weak ones to assure their ... ideas, to put questions to the teachers, to show their disagreements with the teachers Teachers, on the other hand, are no longer “knowledge-transmitter” They play the role of a facilitator of the ... a theoretical background to the study, this chapter is devoted to the reexamination of the concepts most relevant to the thesis’s topic Firstly, an account of the CLT theory is made Secondly,...
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Manifestation Manifesto: From the World Within to the World Without
... the term "cut to the chase" has its origin in the film industry "Cut" or edit the film to the chase sequence It means get to the most exciting part of the movie right away the chase This is the ... are the easiest tool to use to manifest what you desire They are easy to create (or to find) and easy to repeat It is the repetition that passes them over to memory (and thus the subconscious ... is to clarify one of the steps I have listed here What I have attempted to in this Manifestation Manifesto is to cut to the chase of what I think you need to know to manifest what you want By the...
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Overview of Plant Biotechnology from Its Early Roots to the Present
... “FlavR Saver.” This tomato has two distinct advantages over other tomato cultivars: first, it has a longer shelf life in storage, and second, the fruit of this tomato could be left on the plant until ... on the structural elucidation of these unique secondary metabolites, applying modern techniques of analysis We then come to the conclusion as to what plant biotechnology is all about: it aims to ... compounds Most of these natural products are generally not essential for the basic metabolic processes of the plant but are often critical to the proper functioning of the plant in relation to its environment...
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Tài liệu Using Stored Procedures to Add, Modify, and Remove Rows from the Database phần 1 pdf
... objects from your DataSet, and then call the Update() method of your DataAdapter, the appropriate stored procedure is run to push your changes to the database Let's take a look at how to set the ... (described in Chapter 4) to record the attempt to delete the row from the Products table In this example, you must use SET NOCOUNT ON before performing the INSERT into the ProductAudit table, ... run when you call the mySqlDataAdapter object's Fill() method to retrieve rows from the Products table into a DataSet Before you can push changes to the database, you must set the InsertCommand,...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25