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from clinical trials to real world

Báo cáo khoa học:

Báo cáo khoa học: "Evidence-based medicine: Classifying the evidence from clinical trials – the need to consider other dimension" pot

Báo cáo khoa học

... need to consider refinement of how we currently classify the quality of evidence according to study design At a minimum, this should include principles on how to classify device and protocol trials ... consideration in the context of trials of equivalency or non-superiority and for trials that are stopped at interim analyses for early benefit [21-23] Finally, future trials need to address whether estimates ... power of the investigator-protagonist needs to be taken into account Such investigators, when involved in single center studies, especially unblinded ones, have the power to profoundly influence...
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Báo cáo y học:

Báo cáo y học: " What have we learned from clinical trials in primary Sjögren’s syndrome about pathogenesis" ppsx

Báo cáo khoa học

... levels of proinflammatory cytokines Scand J Rheumatol 2009, 38:386-389 11 Sisto M, D’Amore M, Caprio S, Mitolo V, Scagliusi P, Lisi S: Tumor necrosis factor inhibitors block apoptosis of human epithelial ... monoclonal antibodies to IFNα seems a rational approach Monoclonal Page of antibodies to IFNα are currently available and clinical trials in systemic lupus erythematosus and dermatomyositis/polymyositis ... B-cell activating factor; CTLA4, cytotoxic T-lymphocyte antigen 4; mAb, monoclonal antibody; RCT, randomized controlled trial; Rec, receptor ; TACI, transmembrane activator and calcium-modulating...
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Java & XML 2nd Edition solutions to real world problems phần 1 potx

Java & XML 2nd Edition solutions to real world problems phần 1 potx

Kỹ thuật lập trình

... of XML, and trying to find the right one is not an easy task I've got to pick out twelve or thirteen key topics from these hundreds, and manage to make them all applicable to you; not an easy ... others need to be downloaded manually I'll expect you to either have these on hand, or be able to get them from an Internet web site, so ensure you've got web access before getting too far into any ... related documents in this chapter to illustrate the concepts in this primer You might want to take the time to either type these into your editor or download them from the book's web site (http://www.newinstance.com/),...
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Java & XML 2nd Edition solutions to real world problems phần 2 doc

Java & XML 2nd Edition solutions to real world problems phần 2 doc

Kỹ thuật lập trình

... ContentHandler { /** Hold onto the locator for location information */ private Locator locator; /** Store URI to prefix mappings */ private Map namespaceMappings; /** Tree Model to add nodes to */ private ... make is to hold a reference to the Locator object within a class member variable outside of the callback method: public void setDocumentLocator(Locator locator) { // Saving the Locator to a class ... length parameters, to signify which index to start at and how far to read into the array This can cause some confusion; a common mistake is to include code like this example to read from the character...
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Java & XML 2nd Edition solutions to real world problems phần 3 pdf

Java & XML 2nd Edition solutions to real world problems phần 3 pdf

Kỹ thuật lập trình

... number="2"> ... and Bolts"> ... title="Introduction" number="1">
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Java & XML 2nd Edition solutions to real world problems phần 4 potx

Java & XML 2nd Edition solutions to real world problems phần 4 potx

Kỹ thuật lập trình

... "adirondack top" (which to a guitar lover obviously applies to the wood on the top of a guitar) to return toys ("top") from a particular mountain range ("Adirondack") The best way to this in the ... may be more used to in working with XML by now 6.3.2.1 NodeIterator I want to get past all the conceptualization and into the code sample I referred to earlier I want access to all content within ... refer to as "the dreaded WRONG DOCUMENT exception." This exception occurs when you try to mix nodes from different documents It most often shows up when you try to move a node from one document to...
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Java & XML 2nd Edition solutions to real world problems phần 5 pot

Java & XML 2nd Edition solutions to real world problems phần 5 pot

Kỹ thuật lập trình

... of the factory, as shown here: // Get the factory TransformerFactory factory = TransformerFactory.newInstance( ); // Configure the factory factory.setErrorResolver(myErrorResolver); factory.setURIResolver(myURIResolver); ... JDOMException { // Create builder and set up factory SAXBuilder builder = new SAXBuilder( ); JDOMFactory factory = new CustomJDOMFactory( ); builder.setFactory(factory); // Build document Document doc ... SAX 2.0 went from beta to final, and really threw things into a mess However, that hasn't stopped many who didn't need these later versions of DOM and SAX from putting JAXP 1.0 into production,...
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Java & XML 2nd Edition solutions to real world problems phần 6 doc

Java & XML 2nd Edition solutions to real world problems phần 6 doc

Kỹ thuật lập trình

... directory to Tomcat's webapps directory You should have a directory structure similar to Figure 10-1 Figure 10-1 Cocoon context directory structure With this setup, you'll need to copy a few files from ... and how to use XML-RPC from the world of Java I also spend some time at the end of this chapter looking at real- world applications of XML-RPC, trying to shed some light not only on how to use ... Tomcat's library directory This is located at TOMCAT_HOME/lib, where TOMCAT_HOME is the directory of your Tomcat installation On my Windows machine, this is c:\java\jakarta-tomcat, and on Linux...
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Java & XML 2nd Edition solutions to real world problems phần 7 pptx

Java & XML 2nd Edition solutions to real world problems phần 7 pptx

Kỹ thuật lập trình

... String is inserted into the Vector result list, and this list is returned to the client Now add the required import statement and the code to return the events in the store to the scheduler code: ... end to move to a SOAP-based architecture if needed 12.3.2.2 Deployment descriptors With the Java coding done, you now need to define a deployment descriptor This specifies several key things to ... descriptor for your service, which I just talked about Second, you need to make the classes for your service available to the SOAP server The best way to this is to jar up the service class from...
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Java & XML 2nd Edition solutions to real world problems phần 8 pps

Java & XML 2nd Edition solutions to real world problems phần 8 pps

Kỹ thuật lập trình

... Moving out to mytechbooks.com and then the customers of the bookstore, I show you how to enable this business -to- business (to- customer) application by using XML as a communication tool between ... descriptor that details the serialization issues related to this custom type Add the following lines to the deployment descriptor for the CD catalog, as well as changing the available method names to ... specify a class to convert from Java to XML and from XML to Java, respectively I've used the incredibly handy BeanSerializer class, also provided with Apache SOAP If your custom parameter is...
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Java & XML 2nd Edition solutions to real world problems phần 9 pot

Java & XML 2nd Edition solutions to real world problems phần 9 pot

Kỹ thuật lập trình

... $TOMCAT_HOME/webapps/javaxml2/WEB-INF/classes/javaxml2/castor/ ItemDescriptor.class $TOMCAT_HOME/webapps/javaxml2/WEB-INF/classes/javaxml2/castor/ ItemDescriptor$1.class $TOMCAT_HOME/webapps/javaxml2/WEB-INF/classes/javaxml2/castor/ ItemDescriptor$2.class ... CatalogDescriptor.class $TOMCAT_HOME/webapps/javaxml2/WEB-INF/classes/javaxml2/castor/ CatalogDescriptor$1.class $TOMCAT_HOME/webapps/javaxml2/WEB-INF/classes/javaxml2/castor/Item.class $TOMCAT_HOME/webapps/javaxml2/WEB-INF/classes/javaxml2/castor/ ... classes with Castor is a piece of cake You'll need to use the org.exolab.castor.builder.SourceGenerator class, as shown here: java org.exolab.castor.builder.SourceGenerator -i castor/catalog.xsd...
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Java & XML 2nd Edition solutions to real world problems phần 10 pptx

Java & XML 2nd Edition solutions to real world problems phần 10 pptx

Kỹ thuật lập trình

... void setFactory(JDOMFactory factory); A.4.3.3 JDOMFactory This interface allows users to provide their own factories that produce JDOM constructs (Element, Attribute, etc.) When a factory implementation ... XPointer on top of XLink; the specs build very naturally on each other, and are intended to work together First, you want to take a look at the target document you are going to link to If you can, ... column numbers public class LocatorImpl implements Locator { public LocatorImpl( ); public LocatorImpl(Locator locator); // Implementation of Locator interface } // Additional methods public void...
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Báo cáo y học:

Báo cáo y học: "Evaluation of pathogen detection from clinical samples by real-time polymerase chain reaction using a sepsis pathogen DNA detection kit" pdf

Báo cáo khoa học

... testing for micro-organisms using a real- time polymerase chain reaction that is coupled to melting curve analysis This kit can identify up to 25 organisms from four different microbial groups, ... a total of 407 samples from 212 treated or untreated patients in the departments of surgery, hematology, emergency, cardiopulmonary and ICU, who were suspected of having systematic inflammatory ... them to one commercial laboratory to confirm the validation of the identification microorganisms Blood collection EDTA-2K vacuum blood collection tubes (Insepack II-D, Sekisui Chemical Co Ltd., Tokyo,...
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korten - agenda for a new economy; from phantom wealth to real wealth (2009)

korten - agenda for a new economy; from phantom wealth to real wealth (2009)

Tài chính doanh nghiệp

... phantom wealth — money disconnected from the production or possession of anything of real value The Main Street economy is largely engaged in creating real wealth from real resources to meet real ... on economic policy choices that lead to a bottomto-top structural transformation of the economy in order to strengthen community and reallocate resources to where they best serve I have written ... approach The real need, however, goes far beyond pumping new money into the economy to alleviate the consequences of the credit squeeze We need to rebuild the system from the bottom up The recent...
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Multiple knapsack problem with inter related items and its applications to real world problems

Multiple knapsack problem with inter related items and its applications to real world problems

Tổng hợp

... addition to the relocate operator, we have the exchange operator which exchanges the knapsacks of two items Similar to the relocate operator, the exchange operator may help to minimize the overall ... examination Figure allows user to either manually or automatically assign seats to each candidate for each examination The automatic seat assignment engine allocates candidates to their seats in ascending ... CHAPTER HEURISTICS 4.4 Operators In this section, we shall describe in details the three operators, namely the relocate operator, exchange operator and multi-exchange operator that we used in Tabu...
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Management in India: Grow from an Accidental to a Successful Manager in the IT & Knowledge IndustryA real-world, practical book for a professional in his journey to becoming a successful manager in IndiaRahul Goyalprofessional expertise distilled doc

Management in India: Grow from an Accidental to a Successful Manager in the IT & Knowledge IndustryA real-world, practical book for a professional in his journey to becoming a successful manager in IndiaRahul Goyalprofessional expertise distilled doc

Quản trị kinh doanh

... come into work and say, "It's Monday, so I've got to focus on processes today, then Business Impact tomorrow" Can business impact wait until tomorrow? So, what is a manager really supposed to manage? ... are required to deal with information Monitor This one is a generally well-understood role A manager needs to monitor the internal organization as well as gather relevant information from the rest ... to the practical situations you will run into as a manager and develops it into a set of simple how -to guidelines that we all can follow I particularly love the way Rahul has applied candor to...
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Access Control Models: From the real-world to trusted computing potx

Access Control Models: From the real-world to trusted computing potx

An ninh - Bảo mật

... should not be allowed to flow to high-integrity objects – High-integrity is placed at the top of the lattice and low integrity at the bottom Information flows from top to bottom (opposite direction ... object from top secret to a lower level – On military systems, the reference monitor must enforce that objects from one security level cannot be copied into objects of another level, or into a ... to access C with?  Example: X A A creates V with {t,g} X t A B {t,g} t B C V C A t B X X A takes X to C from V A {t,g} V t B g C X V C C B grants to V the X to C X t A B g V B takes g to V from...
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Báo cáo y học:

Báo cáo y học: "Bench-to-bedside review: Mobilizing patients in the intensive care unit – from pathophysiology to clinical trials" pot

Báo cáo khoa học

... Critical Care Vol 13 No Truong et al inflammatory cytokines TNF-α and IL-1β [9,62] Taken together, antioxidant formation and a shift toward anti-inflammatory cytokines during moderate exercise may play ... effects on muscle, immobility can lead to a pro-inflammatory state caused by increased systemic inflammation via increases in pro-inflammatory cytokines In addition to immobility, critically ill patients ... production of anti-inflammatory cytokines [9] Typically, IL-6 (which has anti-inflammatory properties) is the first cytokine to rise during exercise, increasing up to 100-fold greater than pre-exercise...
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Manifestation Manifesto: From the World Within to the World Without

Manifestation Manifesto: From the World Within to the World Without

Tâm lý - Nghệ thuật sống

... Two things have to happen to move this intangible desire from the world within (my head) to the world without (an iPad in my hands) First, I have to manifest the extra money to purchase it (recently ... have to find a store that has it in stock (I'm currently on a waiting list) I think that affirmations are the easiest tool to use to manifest what you desire They are easy to create (or to find) ... to become deliberate creators of our personal reality Habit What we automatically without conscious thought because of repetition It's how we learn our language How to speak How to walk How to...
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TEXTBOOK OF Hepatology From Basic Science to Clinical Practice doc

TEXTBOOK OF Hepatology From Basic Science to Clinical Practice doc

Sức khỏe giới tính

... TTOA01_vol1 3/9/07 10:46 AM Page i TEXTBOOK OF Hepatology From Basic Science to Clinical Practice TTOA01_vol1 3/9/07 10:46 AM Page ii Textbook of Hepatology Third Edition ... highlighted in the text TTOA01_vol1 3/12/07 4:44 PM Page iii TEXTBOOK OF Hepatology From Basic Science to Clinical Practice THIRD EDITION SECTIONS 110 AND INDEX EDITORS ASSOCIATE EDITORS Juan Rodộs MD ... Consultant Hepatologist Beth Israel Deaconess Medical Center Boston, MA, USA Nazia Selzner MD PhD Transplant Hepatology Fellow Multiorgan Transplant Program Toronto General Hospital Toronto, ON, Canada...
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