... UniversityRegional Learning Alliance – workforce development and training/collaborations with business and industry; meeting the training and education needs of businesses within 60 mile radius in Northern Allegheny ... $28,000 in average annual salary)Preserving ValueContinuing education is important to preserving the market value of specialized education – particularly in professional fieldsContinuing education ... UniversitySmall Business Initiative inthe Frehn Center for Management; offering information and assistance to individuals and groups planning to start a new business Indirect Contributions...
... designed on the basis of side-chain packing criteriafrom a modelled structure ofthe enzyme resulted in restor-ation ofthe energy of activation to the levels ofthe nativeenzyme and in an increased ... that the Eavalue in thistemperature range is considerably lowered. On the basis of the model, the behavior ofthe G261A variant can beinterpreted in terms of constraints introduced by the ... respectively. By introducing an Ala residue inthe place of Gly it is expected that the conformational flexibility of the main chain can be constrained with a minimum perturba-tion ofthe local structure,...
... antigen in itself [7,20]. Atleast for these antibodies, theroleofthe VLdomainmight be to increase the affinity by supporting the VHdomain. The phenomenon may also be observed in the chain ... clarify the effect ofthe interface mutations on the antigen-binding affinity. To investigate systematically thisunsought relationship between the antigen-bindingaffinity of Fv and the VH⁄ VLinteraction ... Although the Fv was designed based on HyHEL-10, it is not clearwhether or not H39 is dominantly tuning the VH⁄ VLinteraction of other Fvs, including HyHEL-10. In addition, the effect ofthe H39...
... example, inthe case of questionQ209: “Who invented the paper clip ?”, the expected answer type is PERSON and so is the subject ofthe verb invented , lexicalized as the nominalization inventor. ... mountain; (b) lava IS-PART of vol-cano, and moreover it is a part coming from the inside; and (c) fragments of lava have all the prop-erties of lava, the following question semantic TheRoleof ... Question-Answering TrackExperiments using PIRCS. Proceedings ofthe Text Re-trieval Conference (TREC-9), pages 26–35, 2000.Dan Magerman. Statistical decision-tree models of parsing. In Proceedings of the...
... giving is instrumental in maintaining social ties and serves as a mean of symbolic communication in social relationship. Most ofthe researches before and after the appearance of Sherry’s model ... described in details the stages ofthe whole gift-exchange processes, researchers have examined the influence of many variables within these stages. This model divides gifting activities into ... their brand attitude, may suggest an interesting implication for the new brand advertising strategy. Instead of focusing on the content ofthe message which only emphasizes the benefits of...
... portion ofthe savings in that account for school and whether log of net worth or categorical net worth is included in the model. Moreover, when youth savings is included in regression models, ... school. Conley (2001) finds that a doubling of net worth results in an 8.3% increase inthe probability of attending college. Further, when net worth is included inthe model, Black youth are ... youth. Youth savings. Youth were asked in 2002 whether they had a savings or bank account in their name. If they had an account, they were also asked whether they were saving some of this money...
... that the increase of Glc6P inthe presence of S4048 was caused by the inhibition of Glc6P hydro-lysis inthe absence of detectable changes in glucosephosphorylation.S4048 causes inactivation of ... glu-cokinase and hexokinase I in distinct pools [3,24], orby the involvement of mechanisms, additional toGlc6P, in mediating the effects of glucokinase over-expression. As glucokinase binds ... control of glycolysis and glycogen synthesis by glucokinase overexpres-sion. The validity of S4048 for testing theroleof Glc6P was supported byits lack of effect on glucokinase binding and...
... documents and find that the fea-ture vectors corresponding to some of these docu-ments (particularly the short ones) have all zeroes in them. In other words, none ofthe bigrams from the training set ... cap-turing two different situations, one in which the author himself likes the movie, and inthe other, the author’s cousin likes the movie. The over-generalization resulting from these “stemmed” ... available.612 Proceedings ofthe COLING/ACL 2006 Main Conference Poster Sessions, pages 611–618,Sydney, July 2006.c2006 Association for Computational LinguisticsExamining theRoleof Linguistic Knowledge...
... tightbinding affinity was demonstrated towards lauric acid,resulting inthe synthesis of mainly x-1 hydroxylatedlauric acid, suggesting a roleinthe lipid oxidativemetabolism. Interestingly, the ... enzymes. The FUM6 protein (CYP505B1) inter-venes in one ofthe first steps in fumonisin synthesis byhydroxylation ofthe polyketide-amino acid at C-14and C-15 (Fig. 3). Fum6 deletion mutants of F. ... occurring in the soil. Furthermore, branched chain fatty acids make up80% ofthe fatty acid content ofthe Bacillus sp. mem-branes and when the hydroxylation of these substrateswas studied in...
... the transaction from the vantage point of firm A, the floating-rate payer. The cost of synthetic floating-rate financing is determined by the cost of servicing fixed-rate debt plus the net cost of ... to the desire on the part of firms to hedge cash flows against the effects of interest rate volatility. The timing ofthe appearance of interest rate swaps, coming as it did during a pe-riod of ... perhaps the best-known exposition of this viewpoint, which is based on the principle of comparative advantage. In international trade theory, the principle of comparative advantage explains the economic...
... rapidly, causing the unfolding of one of the I27 modules inthe chain. Unfolding then extends the over-all length ofthe protein, relaxing the pulling force to a lowvalue. As the slack inthe length ... stretching a polyprotein re-sults in a well-defined series of step increases in length, mark-ing the unfolding and extension ofthe individual modules in the chain.[37] The size ofthe observed steps ... b-strands ofthe I27 protein during the main unfold-ing barrier.[39]To further validate this view and gain insight into the roleof solvent hydrogen bonds in protein unfolding, werepeated these...
... of a federation and so are said to operate inthe interest ofthe users rather than inthe interest ofthe service providers. These service providers are called “relying parties.” In this model, ... build-up of profiles that others hold about him. Method of linking accounts/ learning if they belong to the same person There is no linking between accounts and no information flow between them. ... managing and protecting digital identities, with a view to strengthening confidence inthe online activities crucial to the growth ofthe Internet Economy. The primer is a product ofthe Working...
... (glycero-)sphingolipids. In addition the fatty acid chains ofthe phospholipids composingthese rigid domains are generally more saturated thanthose inthe lipids ofthe surrounding membrane. In fact, this ... dur-ing lipid raft isolation. Moreover, these studies haveprovided some insights into the significance of the localization ofthe P2X7receptors in lipid rafts regard-ing the regulation of intracellular ... muscarinic receptors, endo-thelin receptors, rhodopsin) are located in lipid rafts[65–70] where they are in close proximity to theirtransducing GTP-binding protein (Gs, Gi, Go, Gq andtransducin...
... suggested by the lack of coincidence of the changes in relative fluorescence intensity and in kand by the hysteresis ofthe reversibility process(Fig. 4). At the end ofthe transition, the intrinsic ... that of the wild-type; however, the integrity ofthe calcium bind-ing site formed by Asp287 and Glu53 is essential forinteraction with the cation in 7.9 m GdmCl.An interesting finding ofthe ... pfLamA inthe native state, indepen-dently of their interaction with calcium. Therole of electrostatic interactions in protein stability has beenwidely investigated and the stabilizing effect of...