disubstituted benzenes ortho meta and para substitution
Tài liệu Báo cáo khoa học:Symmetric fluoro-substituted diol-based HIV protease inhibitors Ortho-fluorinated and meta-fluorinated P1/P1¢-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacyy docx
... and Fo–Fc, unambiguously indicate the conformation of the inhibitors and the position of the fluorine substitutions in P1/P1¢ (Fig 1) Structural accommodations in response to ortho- , metaand para- fluoro-substituted ... position of fluoro -substitution on the benzyloxy side group, para being greater than ortho and ortho greater than meta Among the fluoro-substituted inhibitors, the most potent was the disubstituted ... (http://www.expasy.ch/spdbv/) and 3D-rendered with POV-RAY (http://www.povray.org/) ortho, meta and para positions on the P1-benzyloxy side ˚ groups are in the range of 0.3–0.4 A, and are mainly observed...
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Prepositions por and para
... padre 24 Prepositions por and para ii Paired activity Objective – To understand the differences between por and para Method – Engage in a discussion to work out why por and para are used in the following ... Destination Tengo un mensaje para ti Saca un billete para Santander I’ve got a message for you He’s buying a ticket for Santander iii Going towards a place La cuando voy para la facultad I see her ... (2) (2) (2) (2) Quieren ir para el museo Estoy limpiando la casa para la fiesta Dale el dinero para el regalo El hombre est´ para confesar la verdad a Hace la tarea para m´ ı Now, each pair finds...
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báo cáo khoa học: " Drug use and opioid substitution treatment for prisoners" pot
... administration and administration of the OST programme; medical and nursing staffs to execute maintenance therapy assessments, administration and delivery; pharmacy and courier services for stocking, preparation ... suicide and self-harm in prison and to death upon release from prison because of accidental opioid overdose, prison regimen services that correspond to national and international good practice and ... crime and, consequently, lower risk for re-incarceration and lower risks for violence, potentially lethal overdose [18] and infectious disease [44] Overcoming barriers from the prison staff and...
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Báo cáo y học: "Association between regulated upon activation, normal T cells expressed and secreted (RANTES) -28C/G polymorphism and asthma risk – A Meta-Analysis"
... Table and Figure 1) We further performed stratified analysis according to asthma type (atopic asthma and non-atopic asthma), age (children and adult) and ethnicity (Asian and Caucasian and African ... heterogeneity, and it was considered significant for P < 0.01 We used the fixed-effects model and the random-effects model based on the Mantel-Haenszel method and the DerSimonian and Laird method, ... (777 cases and 495 controls); case-control studies of age (1894 cases and 1766 controls) and case-control studies of ethnicity (1894 cases and 1766 controls) were available for this meta- analysis...
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Báo cáo y học: "Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis"
... gene causes CS)) and XPV have been identified [6] XPA, ERCC3/XPB, ERCC2/XPD, ERCC4/XPF and ERCC5/XPG have a defect in TCR and GGR, while XPC and XPE have a defect in GGR only ERCC6 and ERCC8 are ... (0.78 3.05) Sequencing Replication (random samples) Replication (random samples) Replication (random samples) Replication (random samples) Replication (random samples) None Caucasian 96/94 Population ... Replication (random samples) Replication (random samples) Replication (random samples) Replication (all samples) None Replication (random samples) Replication (all samples) Replication (random samples)...
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Contrastive analysis of nominal substitution english and vietnamese discourse
... similarities between substitution and reference 1.3 Differences and similarities between substitution and ellipsis 1.4 Nominal substitution .8 1.5 General features of English and Vietnamese ... Analysis Of Nominal Substitution In English And Vietnamese Discourse Part II Content Chapter One: In general 1.1 What is substitution and types of substitution Much has been said about substitution ... has been mentioned above, ellipsis and substitution should be seen as two different processes and be dealt with separately 1.4 Nominal substitution Nominal substitution takes place mainly in...
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A study on ambiguity caused by ellipsis and substitution in english = nghiên cứu về sự mập mờ về nghĩa gây ra do phép tỉnh lược và phép thay thế trong tiếng anh luận văn tốt nghiệp đại học
... of substitution and types of substitution • Investigate the circumstances in which ellipsis and substitution usually cause ambiguity • Indicate the main ambiguities caused by ellipsis and substitution ... understanding about ellipsis and substitution and their ambiguity In addition, the study is implemented with the hope to make a little contribution to solve ambiguity caused by ellipsis and substitution ... circumstances ellipsis and substitution usually cause ambiguity? What are the main types of ambiguity caused by ellipsis and substitution? How to avoid ambiguity caused by ellipsis and substitution? ...
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Tài liệu Democracy and Economic Growth: A meta-analysis pptx
... of applications of meta- analysis to political science (Lau 1999 and Roscoe and Jenkins 2005) and political economy (Nijkamp and Poot 2004 and Doucouliagos and Ulubasoglu 2006) Meta- analysis considers ... demands on areas such as education, justice and health, and encourage stable and longrun growth (Rodrik 1999, Lake and Baum 2001, Baum and Lake 2003) Opponents of democracy, other other hand, ... addition to traditional meta- analysis estimators, we use also the bootstrap and clustered data analysis, as well as Fixed and Random Effects meta- regression models Our meta- analysis derives several...
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Tài liệu Báo cáo " The effect of cobalt substitution on structure and magnetic properties of nickel ferrite " pptx
... Ni2+ (0.74 Å) and Fe3+ (0.67 Å) ions Lattice parameters (Å) 8.38 8.37 8.36 8.35 8.34 8.33 0.0 0.2 0.4 0.6 0.8 X Fig Lattice parameters of Ni1-xCox Fe2O4 Table Calculated lattice parameter ‘a’, ... Fig.2 it is observed that lattice parameter varies from 8.334 Å to 8.382 Å with increasing Co2+ content and they are tabulated in Table This increase of lattice parameter with Co2+ due to the difference ... the ionic radii of constituent ions causing increase in lattice parameter and the densities of pure cobalt ferrite (5.29 g/cm3) and pure nickel ferrite (5.38 g/cm3) The obtained XRD patterns of...
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Tài liệu Báo cáo khoa học: Domain deletions and substitutions in the modular protein evolution doc
... (physical domain deletion, substitution and shadow domains) and two types of annotation artefacts (camouflage and erosion) In the case of physical deletions, shadow domains and erosions, the numbers ... that, by and large, the modular evolution of proteins is dominated by two major types of events: fusion, on the one hand, and deletion and fission on the other [3,4,21,28] Exon shuffling and recombination ... all domain positions the number of camouflage and substitution events have been calculated in the same way, relative frequencies of the camouflage and substitution events at different positions can...
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Tài liệu Báo cáo Y học: A novel meta-cleavage dioxygenase that cleaves a carboxyl-groupsubstituted 2-aminophenol Purification and characterization of 4-amino-3-hydroxybenzoate 2,3-dioxygenase from Bordetella sp. strain 10d doc
... 1,2,4-trihydroxybenzene and pyrogallol) in aqueous solution were always freshly prepared and used immediately Effect of various compounds on the enzyme activity The effect of metal salts, and chelating and sulfhydryl ... (0.16 mM) to 85% Inhibition by metal salts and other compounds Among the metal salts tested, the enzyme was completely inhibited by mM HgCl2 and mM CuSO4 while mM FeSO4 and mM Fe(NH4)2(SO4)2 slightly ... Samples were taken and 4-amino-3-hydroxybenzoic acid was quantified by the methods described below Morphological and phenotypic characterization Physiological and biochemical parameters, such as...
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Tài liệu Growths and Carbon Stocks of Para Rubber Plantations on Phonpisai Soil Series in Northeastern Thailand ppt
... The top soil is sandy clay loam soil and bottom soil is clay Soil texture in top soil found natural forest and 1, 5, 15 and 20 years old rubber plantations to have sandy clay loam and 10 years old ... bottom soil, natural forest and 20 years old plantations have clay soil, and 10 years old plantations have sandy clay loam to clay and and 15 years old plantation have sandy clay loam to clay soil ... turbidimetry and Ca, Mg, Fe, Mn, Cu and Zn by atomic absorption spectrophotometry) and B (burned with CaCO3, dissolved in : of HCl : water, and analyzed the concentration by azomethine-H method) (Tandon,...
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Báo cáo khoa học: Alternative splicing: good and bad effects of translationally silent substitutions pdf
... trans-acting factors that regulate splicing [4] Both intronic and synonymous nucleotide substitutions can sufficiently alter splicing and cause genetic disease A list of silent mutations associated ... evolution based on the Ka ⁄ Ks ratio (where Ka is the ratio of nonsynonymous substitutions and Ks is the ratio of synonymous substitutions) This method, where the metric is based on the neutrality ... splicing exon has a better chance of being tolerated by the cell metabolism and is then free to evolve Integrating evolutionary and splicing disease-related mechanistic studies – an example The...
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Báo cáo khoa học: "Bayesian Synchronous Tree-Substitution Grammar Induction and its Application to Sentence Compression" pdf
... deleting compression rules, and was initialized uniformly Each EM instance was characterized by two parameters: α, the smoothing parameter for MAP-EM, and δ, the smoothing parameter for augmenting ... judgments of GS, EM, and SVM output sentences and the gold standard in terms of grammaticality (how fluent the compression is) and importance (how much of the meaning of and important information ... test set and used the Stanford parser to extract grammatical relations from predicted trees and the gold standard We computed precision, recall, RelF1 (all based on grammatical relations), and compression...
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Báo cáo khoa học: "A Meta-Level Grammar: Redefining Synchronous TAG for Translation and Paraphrase" doc
... substructures regardless of intervening material, and this is suggestive of TAG's EDL The paraphrase in (4) and in Figures and 7, and other paraphrase examples, strongly suggest that these more ... nodes at the metameta level For (5), the meta- level grammar for the left projection then looks as in Figure 9, and for the right projection as in Figure 10 • Figure 11 contains the meta- meta-level ... effect will occur at the metameta level that required the meta- grammar in the first place, leading perhaps to an infinite (and useless) sequence? The intuition is that it is the meta- level, rather...
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Báo cáo khoa học: "Finding Word Substitutions Using a Distributional Similarity Baseline and Immediate Context Overlap" potx
... ‘murder’ and ‘abduct’ kill murder abduct two birds with babies that life her and make cancer cells and his wife and an innocent man a mocking bird thousands of innocent unsuspecting people and or ... unsuspecting people and or die for women and children suspects in foreign or be killed her husband and a young girl another human being in the name and forcibly recruit thousands of people in connection ... Recently, systems that combine both patternbased and feature vector approaches have also been presented Lin et al (2003) and Pantel and Ravichandran (2004) have proposed to classify the output...
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Tobacco Smoke, Indoor Air Pollution and Tuberculosis: A Systematic Review and Meta-Analysis potx
... oils’’ ‘‘(1) AND (2)’’ OR ‘‘(1) AND (3)’’ OR ‘‘(1) AND (4)’’ OR ‘‘(1) AND (5)’’ 0174 January 2007 | Volume | Issue | e20 Tobacco and Biomass Smoke and TB Figure Flow Diagram of Study Steps and Exclusions ... smoking Current and former smoking Current and former tobacco smoking and use of biomass cooking fuels Current and former tobacco smoking Current and former tobacco smoking Current and former tobacco ... ‘‘(7) AND (8)’’ OR ‘‘(7) AND (9)’’ OR ‘‘(7) AND (10)’’ OR ‘‘(7) AND (11)’’ 13 (6) OR (12) 10 11 12 were available, we included only the one with the most detailed information for both outcome and...
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A meta analysis and risk assessment of heavy metal uptake in common garden vegestable
... Trace metal deficiencies in plants have been associated with increases in heavy metal uptake (Khan and Frankland 1983) Soil pH significantly influences heavy metal concentrations in both soil and ... 42 12 Raw Data for Weighting and Combining Using Meta- analysis 59 13 R, R2, Slope and Y-intercept Values Combined From Like Plant-Metal Groups and the Number of Studies in Each Group ... may include mining and smelting of ores, electroplating operations, fungicides and pesticides, sewage and sludge from treatment plants, and the burning of fossil fuels (John and VanLaerhoven 1972;...
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Báo cáo khoa học: Structural and functional consequences of single amino acid substitutions in the pyrimidine base binding pocket of Escherichia coli CMP kinase pdf
... Comparative structures of CMP and UMP, and interactions between the cytosine moiety of nucleotide and various side chains of wild-type CMP kinase (Upper) Chemical differences between CMP and ... NMPs (A37 and T39 in these enzymes are equivalent to S36 in E coli CMP kinase) Substitution of R110 with Met in E coli CMP kinase affected both kcat and Km The kcat Km ratio with CMP and dCMP ... CORE, the LID and the NMPbind [1] A characteristic of bacterial CMP kinases is an extension of the NMPbind domain by 40 amino acid residues forming a three-stranded antiparallel b sheet and two a...
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Báo cáo khoa học: Effect of valine 106 on structure–function relation of cytosolic human thymidine kinase Kinetic properties and oligomerization pattern of nine substitution mutants of V106 ppt
... glycerol and mM dithiothreitol) with and without 2.5 mM ATP, and incubated on ice for h before storage at )80 °C The enzymes incubated and stored with and without ATP are referred to as the +ATP and ... [28] The amino acid sequence identity is 34% between dNK and dGK [29], and 47% between dGK and dCK [28], and the structures of dNK, dGK and dCK appeared to be very similar [27,28] Despite the ... on both strands with SequenaseTM version 2.0 DNA Sequencing Kit (Amersham Biosciences) Expression and purification of rLy-TK1 recombinant enzymes and rLy-TK166)136 proteins Expression and purification...
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